Enzymology of Benzylisoquinoline Alkaloid Formation

1985 ◽  
pp. 240-256 ◽  
Author(s):  
M. H. Zenk
Keyword(s):  
Benzylisoquinoline Alkaloid

TISSUE DISTRIBUTION OF TRANSCRIPTS INVOLVED IN BIOSYNTHESIS OF BENZYLISOQUINOLINE ALKALOID IN MATURE PLANTS OF Argemone mexicana L. (Papaveraceae)

2018 ◽  
Vol 41 (1) ◽  
pp. 13-21 ◽  
Author(s):  
Felipe Vázquez-Flota ◽  
Jorge Rubio-Piña ◽  
Jorge Xool-Tamayo ◽  
Mariela Vergara-Olivares ◽  
Yahaira Tamayo-Ordoñez ◽  
...  
Keyword(s):  
Tissue Distribution ◽  
Transport Mechanism ◽  
Gene Products ◽  
Argemone Mexicana ◽  
Benzylisoquinoline Alkaloid ◽  
Stems And Leaves ◽  
Specific Reactions

The distribution of berberine and sanguinarine was analyzed in roots, stems and leaves of mature Argemone mexicana plants, along with that of transcripts corresponding to selected genes involved in both early biosynthetic reactions, which are common to both alkaloids, and in the late specific reactions conducting to the formation of each of them. Roots were the main sites of alkaloid accumulation, though they showed the lowest accumulation of the analyzed transcripts. Results are discussed in terms of the operation of a possible transport mechanism of alkaloids between the aerial tissues and the roots, or the occurrence of different biosynthetic alternative reactions in both parts, aerial and underground tissues, involving different gene products, yet with similar catalytic capacities.

scholarly journals Transcriptional Profiles of Secondary Metabolite Biosynthesis Genes and Cytochromes in the Leaves of Four Papaver Species

Data ◽  
2018 ◽  
Vol 3 (4) ◽  
pp. 55 ◽  
Author(s):  
Dowan Kim ◽  
Myunghee Jung ◽  
In Ha ◽  
Min Lee ◽  
Seok-Geun Lee ◽  
...  
Keyword(s):  
Secondary Metabolite ◽  
Developmental Stages ◽  
Expression Profiles ◽  
Bioinformatics Analyses ◽  
Kegg Pathways ◽  
Benzylisoquinoline Alkaloid ◽  
Development Life Cycle ◽  
The Family ◽  
Leaf Transcriptome ◽  
Secondary Metabolite Biosynthesis

Poppies are well-known plants in the family Papaveraceae that are rich in alkaloids. This family contains 61 species, and in this study we sequenced the transcriptomes of four species’ (Papaver rhoeas, Papaver nudicaule, Papaver fauriei, and Papaver somniferum) leaves. These transcripts were systematically assessed for the expression of secondary metabolite biosynthesis (SMB) genes and cytochromes, and their expression profiles were assessed for use in bioinformatics analyses. This study contributed 265 Gb (13 libraries with three biological replicates) of leaf transcriptome data from three Papaver plant developmental stages. Sequenced transcripts were assembled into 815 Mb of contigs, including 226 Mb of full-length transcripts. The transcripts for 53 KEGG pathways, 55 cytochrome superfamilies, and benzylisoquinoline alkaloid biosynthesis (BIA) were identified and compared to four other alkaloid-rich genomes. Additionally, 22 different alkaloids and their relative expression profiles in three developmental stages of Papaver species were assessed by targeted metabolomics using LC-QTOF-MS/MS. Collectively, the results are given in co-occurrence heat-maps to help researchers obtain an overview of the transcripts and their differential expression in the Papaver development life cycle, particularly in leaves. Moreover, this dataset will be a valuable resource to derive hypotheses to mitigate an array of Papaver developmental and secondary metabolite biosynthesis issues in the future.

A new benzylisoquinoline alkaloid from stems of Nelumbo nucifera

2008 ◽  
Vol 19 (3) ◽  
pp. 308-310 ◽  
Author(s):  
Xu Hong Duan ◽  
Jian Qin Jiang
Keyword(s):  
Nelumbo Nucifera ◽  
Benzylisoquinoline Alkaloid

scholarly journals Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis

2021 ◽  
pp. 101211
Author(s):  
Samuel C. Carr ◽  
Megan A. Torres ◽  
Jeremy S. Morris ◽  
Peter J. Facchini ◽  
Kenneth K.S. Ng
Keyword(s):  
Structural Studies ◽  
Alkaloid Biosynthesis ◽  
Benzylisoquinoline Alkaloid

scholarly journals Fluorescence switching of sanguinarine in micellar environments

2015 ◽  
Vol 17 (32) ◽  
pp. 20725-20732 ◽  
Author(s):  
Sagar Satpathi ◽  
Krishna Gavvala ◽  
Partha Hazra
Keyword(s):  
Benzylisoquinoline Alkaloid ◽  
Fluorescence Switch ◽  
Fluorescence Switching

Conversion from iminium to alkanolamine form of Sanguinarine, a key member of benzylisoquinoline alkaloid family, is monitored in micellar environments by fluorescence switch.

scholarly journals Hairy root induction and benzylisoquinoline alkaloid production in Macleaya cordata

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Peng Huang ◽  
Liqiong Xia ◽  
Wei Liu ◽  
Ruolan Jiang ◽  
Xiubin Liu ◽  
...  
Keyword(s):  
Hairy Root ◽  
Root Induction ◽  
Alkaloid Production ◽  
Benzylisoquinoline Alkaloid ◽  
Macleaya Cordata ◽  
Hairy Root Induction

Enzymatic biosynthesis of benzylisoquinoline alkaloid glycosides via promiscuous glycosyltransferases from Carthamus tinctorius

2019 ◽  
Vol 30 (2) ◽  
pp. 443-446 ◽  
Author(s):  
Yujiao Zhang ◽  
Kebo Xie ◽  
Aijing Liu ◽  
Ridao Chen ◽  
Dawei Chen ◽  
...  
Keyword(s):  
Carthamus Tinctorius ◽  
Benzylisoquinoline Alkaloid
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