Modulation of Cytotoxic T Lymphocyte Function by Cyclic 3′,5′-Mononucleotides

1974 ◽  
pp. 209-222
Author(s):  
T. B. Strom ◽  
A. Deisseroth ◽  
J. Morganroth ◽  
C. B. Carpenter ◽  
J. P. Merrill
Keyword(s):  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
Lymphocyte Function

The roles of CD8 in cytotoxic T lymphocyte function

1993 ◽  
Vol 14 (4) ◽  
pp. 177-183 ◽  
Author(s):  
Anne M. O'Rourke ◽  
Matthew F. Mescher
Keyword(s):  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
Lymphocyte Function

scholarly journals Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function

2014 ◽  
Vol 35 (8) ◽  
pp. 1788-1797 ◽  
Author(s):  
Edward P. Chen ◽  
Nune Markosyan ◽  
Emma Connolly ◽  
John A. Lawson ◽  
Xuanwen Li ◽  
...  
Keyword(s):  
Tumor Growth ◽  
T Lymphocyte ◽  
Mammary Tumor ◽  
Cytotoxic T Lymphocyte ◽  
Myeloid Cell ◽  
Lymphocyte Function ◽  
Mammary Tumor Growth ◽  
Cox 2

LOSS OF CYTOTOXIC T LYMPHOCYTE FUNCTION IN CHEDIAK-HIGASHI SYNDROME ARISES FROM A SECRETORY DEFECT THAT PREVENTS LYTIC GRANULE EXOCYTOSIS

PEDIATRICS ◽  
1996 ◽  
Vol 98 (2) ◽  
pp. 349-349
Author(s):  
Kathleen E. Sullivan
Keyword(s):  
T Cells ◽  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
Cytotoxic T Cells ◽  
Molecular Defect ◽  
Lymphocyte Function ◽  
Lytic Granules ◽  
Hematopoietic Lineage ◽  
Chediak Higashi Syndrome ◽  
Lytic Granule

Cytotoxic T cells from a patient with chediak-Higashi syndrome formed giant lytic granules that were not secreted in response to stimulation. This led to abnormal cytolytic function. The authors conclude that the molecular defect in Chediak-Higashi syndrome lies in a protein that is generally involved in vesicle fusion and is crucial for the secretion of lysosomal contents for cells of the hematopoietic lineage.

scholarly journals Targeted calcium influx boosts cytotoxic T lymphocyte function in the tumour microenvironment

2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Kyun-Do Kim ◽  
Seyeon Bae ◽  
Tara Capece ◽  
Hristina Nedelkovska ◽  
Rafael G. de Rubio ◽  
...  
Keyword(s):  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
Calcium Influx ◽  
Tumour Microenvironment ◽  
Lymphocyte Function

scholarly journals Interleukin-12 is necessary for the priming of CD4+T cells required during the elicitation of HIV-1 gp120-specific cytotoxic T-lymphocyte function

Immunology ◽  
2008 ◽  
Vol 124 (4) ◽  
pp. 553-561 ◽  
Author(s):  
Shalini Gupta ◽  
Ramanamurthy Boppana ◽  
Gyan C. Mishra ◽  
Bhaskar Saha ◽  
Debashis Mitra
Keyword(s):  
T Cells ◽  
T Lymphocyte ◽  
Cd4 T Cells ◽  
Cytotoxic T Lymphocyte ◽  
Interleukin 12 ◽  
Lymphocyte Function ◽  
Hiv 1

Inhibition of ex vivo-expanded cytotoxic T-lymphocyte function by high-dose cyclosporine

2003 ◽  
Vol 76 (4) ◽  
pp. 739-740 ◽  
Author(s):  
Xiaoyan Zhan ◽  
Brita Brown ◽  
Karen S. Slobod ◽  
Julia L. Hurwitz
Keyword(s):  
T Lymphocyte ◽  
Cytotoxic T Lymphocyte ◽  
Ex Vivo ◽  
High Dose ◽  
Lymphocyte Function
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