Role of Sphingosine 1-Phosphate in Skeletal Muscle Cell Biology

2013 ◽  
pp. 457-467 ◽  
Author(s):  
Paola Bruni ◽  
Chiara Donati
Keyword(s):  
Skeletal Muscle ◽  
Muscle Cell ◽  
Cell Biology ◽  
Skeletal Muscle Cell ◽  
Sphingosine 1 Phosphate

The Role of Taurine on Skeletal Muscle Cell Differentiation

2013 ◽  
pp. 321-328 ◽  
Author(s):  
Teruo Miyazaki ◽  
Akira Honda ◽  
Tadashi Ikegami ◽  
Yasushi Matsuzaki
Keyword(s):  
Skeletal Muscle ◽  
Cell Differentiation ◽  
Muscle Cell ◽  
Skeletal Muscle Cell ◽  
Muscle Cell Differentiation

scholarly journals The role of resveratrol on skeletal muscle cell differentiation and myotube hypertrophy during glucose restriction

2017 ◽  
Vol 444 (1-2) ◽  
pp. 109-123 ◽  
Author(s):  
Hannah F. Dugdale ◽  
David C. Hughes ◽  
Robert Allan ◽  
Colleen S. Deane ◽  
Christopher R. Coxon ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cell Differentiation ◽  
Muscle Cell ◽  
Skeletal Muscle Cell ◽  
Muscle Cell Differentiation ◽  
Myotube Hypertrophy ◽  
Glucose Restriction

scholarly journals Comment on: Bente Klarlund Peddersen, Physical activity and muscle-brain crosstalk

2020 ◽  
Vol 19 (2) ◽  
pp. 172
Author(s):  
Leandro Paim da Cruz Carvalho ◽  
Jorge Luiz De Brito Gomes
Keyword(s):  
Physical Activity ◽  
Skeletal Muscle ◽  
Friedrich Nietzsche ◽  
Muscle Cell ◽  
Cell Biology ◽  
Recent Article ◽  
Skeletal Muscle Cell ◽  
The Past ◽  
German Philosopher ◽  
The Mind

In the recent article published in Nature Reviews Endocrinology – “Physical activity and muscle-brain crosstalk” [1], the author - Bente Klaurlund Peddersen, a great reference in the study of skeletal muscle cell biology, contextualizes the theme by citing great philosophers of the past and their perceptions about the link between physical activity and the mind. Emphasizing the phrase of the German philosopher Friedrich Nietzsche: “All great thoughts are conceived by walking”....

CoCl2-simulated hypoxia in skeletal muscle cell lines: Role of free radicals in gene up-regulation and induction of apoptosis

2007 ◽  
Vol 41 (4) ◽  
pp. 391-401 ◽  
Author(s):  
Silvia Anna Ciafrè ◽  
Francesco Niola ◽  
Ezio Giorda ◽  
Maria Giulia Farace ◽  
Daniela Caporossi
Keyword(s):  
Skeletal Muscle ◽  
Free Radicals ◽  
Cell Lines ◽  
Muscle Cell ◽  
Skeletal Muscle Cell ◽  
Induction Of Apoptosis ◽  
Simulated Hypoxia

scholarly journals Skeletal Muscle Cell Growth Alters the Lipid Composition of Extracellular Vesicles

Membranes ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 619
Author(s):  
Taylor R. Valentino ◽  
Blake D. Rule ◽  
C. Brooks Mobley ◽  
Mariana Nikolova-Karakashian ◽  
Ivan J. Vechetti
Keyword(s):  
Skeletal Muscle ◽  
Extracellular Vesicles ◽  
Muscle Cell ◽  
Lipid Composition ◽  
Culture Media ◽  
Skeletal Muscle Cell ◽  
Bioactive Lipids ◽  
Hypertrophic Growth ◽  
Sphingosine 1 Phosphate ◽  
Lipid Chain

We sought to characterize the lipid profile of skeletal muscle cell-derived Extracellular Vesicles (EVs) to determine if a hypertrophic stimulus would affect the lipid composition of C2C12 myotube-derived EVs. Analyses included C2C12 murine myoblasts differentiated into myotubes and treated with Insulin-Like Growth Factor 1 (IGF-1) for 24 h to induce hypertrophic growth. EVs were isolated from cell culture media, quantified using Nanoparticle Tracking Analysis (NTA) and analyzed using Transmission Electron Microscopy (TEM). EVs were homogenized and lipids extracted for quantification by Mass Spectrometry followed by downstream lipid class enrichment and lipid chain analysis. IGF-1 treatment elicited an increase in CD63 and CD81 levels (39% and 21%) compared to the controls (16%), respectively. Analysis revealed that skeletal muscle-derived EVs are enriched in bioactive lipids that are likely selectively incorporated into EVs during hypertrophic growth. IGF-1 treatment of myotubes had a significant impact on the levels of diacylglycerol (DG) and ceramide (Cer) in secreted EVs. Specifically, the proportion of unsaturated DG was two- to three-fold higher in EVs derived from IGF-treated cells, as compared to those from control cells. The levels of saturated DG were unaffected. Selective increases were similarly seen in C16- and C24-Cer but not in other species. Levels of free sphingoid bases tended to decrease, while those of sphingosine-1-phosphate was unaffected. Our results suggest that the lipid composition and biogenesis of skeletal muscle-derived EVs, are specific and highly selective during hypertrophic growth.

scholarly journals 16-P029 Skeletal muscle cell fate decisions and the role of Numb

2009 ◽  
Vol 126 ◽  
pp. S270
Author(s):  
Aurélie Jory ◽  
Isabelle Le Roux ◽  
Barbara Gayraud-Morel ◽  
Pierre Rocheteau ◽  
Michel Cohen-Tannoudji ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Cell Fate ◽  
Muscle Cell ◽  
Skeletal Muscle Cell ◽  
Cell Fate Decisions
Sign in / Sign up

Export Citation Format

Share Document