Characteristic Data of Force Transducers Terms and Definitions

Author(s):  
W. Weiler
2019 ◽  
Vol 9 (1) ◽  
pp. 631-640 ◽  
Author(s):  
Leopold Hrabovský ◽  
David Dluhoš

AbstractIn a parking house with KOMA TOWER computer-controlled automated parking system it happens that a control system is locked out of service after a pallet has failed to reach the required position during the shifting of pallets, loaded with cars, into rack cells.In this paper is described testing equipment designed by the Institute of Transport, Faculty of Mechanical Engineering, VŠB Technical University of Ostrava for the purpose of simulating the process of pallets shifting into the rack cells in order that the frequency of error messages from the control system during the automated process of cars positioning in rack cells in the parking house may be limited.The paper details two completed parts of the designed testing equipment which provide for the calibration of strain-gauge force transducers and for the detection of coil compressive spring compression in relation to acting pressure force.The description of the third, principal design part will be provided in the next paper, together with the experimentally measured acting forces which generate, in both horizontal and vertical directions, as a pallet brake pulley rolls along a brake haunch length.


2015 ◽  
Vol 35 (suppl_1) ◽  
Author(s):  
Adam R Wheeler ◽  
Daniel E Kendrick ◽  
Matthew T Allemang ◽  
Andre F Gosling ◽  
Anil Nagavalli ◽  
...  

Objective: Endoscopic vein harvest for lower extremity arterial bypass technique has been questioned due to concern for endothelial damage during procurement. We sought to compare NO mediated endothelial dependent relaxation (EDR) in vein segments harvested with open surgical (OH) versus endoscopic (EH) techniques. Methods: Saphenous vein segments were harvested for lower extremity bypass. 3-4mm vein rings were mounted on force transducers. Segments were mounted in 37° oxygenated Krebs solution and maximally contracted using KCl. NE was used to achieve submaximal contraction. EDR was determined using increasing concentrations of bradykinin (BDK). Endothelial independent relaxation was confirmed using sodium nitroprusside. Two-way ANOVA was used to analyze differences between harvest techniques across BDK concentration. Student t-test was used to examine nitrite levels in each cohort. Results: Vein segments harvested from patients (n=13) led to 28 rings (11 rings; 5 patients EH v. 17;8 OH). Both cohorts achieved moderate relaxation to maximal BDK concentration, [10 -6 M]; (49.5% EH vs. 40.55%, OH, P = .270). Analysis by two way ANOVA for mean % relaxation for BDK concentration [10 -11 - 10 -6 M] showed improved EDR in EH samples compared to OH (P =.029). Mean nitrite tissue bath concentration measurements post-BDK were 279 nM (EH) v. 194 nM (OH) (P = .264). Histology and IHC confirmed intact endothelium by morphometric analysis and CD31 staining. Conclusion: Endothelial function is preserved when utilizing endoscopic harvesting techniques. The advantages of minimally invasive vein procurement for lower extremity bypass can be obtained without concern for damaging venous endothelium.


2005 ◽  
Vol 19 (5) ◽  
pp. 495-502 ◽  
Author(s):  
Michel R. Corboz ◽  
Maria A. Rivelli ◽  
Lori Varty ◽  
Jennifer Mutter ◽  
Mark Cartwright ◽  
...  

Background Functional α1- and α2-adrenoreceptor subtype pharmacology was characterized in an in vitro human nasal mucosa contractile bioassay. Methods Nasal mucosa was obtained from 49 donor patients and mucosal strips were placed in chambers filled with Krebs–Ringer solution and attached to isometric force transducers. Results Nonselective α-adrenoreceptor agonists epinephrine, norepinephrine, and oxymetazoline produced concentration-dependent contractions of isolated human nasal mucosa (pD2= 5.2, 4.9, and 6.5, respectively). The α2-adrenoreceptor agonist BHT-920 (10 μM)–induced contractions were blocked by yohimbine (0.01–1 μM) and prazosin (0.01–1 μM) inhibited the contractile response to the α1-adrenoreceptor agonist phenylephrine (10 μM). Histological analysis showed that phenylephrine and BHT-920 differentially contracted the arteries and veins of human nasal mucosa, respectively. Conclusion Our results indicate that functional α1- and α2-adrenoceptors are present and functional in human nasal mucosa. The a 2-adrenoceptors display a predominant role in contracting the veins and the α1-adrenoceptors appear to preferentially constrict the human nasal arteries.


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