New Achievements in the Field of Intelligent Force Transducers. Traceability

2020 ◽  
pp. 203-216
Author(s):  
Dan Mihai Ştefănescu
Keyword(s):  
2019 ◽  
Vol 9 (1) ◽  
pp. 631-640 ◽  
Author(s):  
Leopold Hrabovský ◽  
David Dluhoš

AbstractIn a parking house with KOMA TOWER computer-controlled automated parking system it happens that a control system is locked out of service after a pallet has failed to reach the required position during the shifting of pallets, loaded with cars, into rack cells.In this paper is described testing equipment designed by the Institute of Transport, Faculty of Mechanical Engineering, VŠB Technical University of Ostrava for the purpose of simulating the process of pallets shifting into the rack cells in order that the frequency of error messages from the control system during the automated process of cars positioning in rack cells in the parking house may be limited.The paper details two completed parts of the designed testing equipment which provide for the calibration of strain-gauge force transducers and for the detection of coil compressive spring compression in relation to acting pressure force.The description of the third, principal design part will be provided in the next paper, together with the experimentally measured acting forces which generate, in both horizontal and vertical directions, as a pallet brake pulley rolls along a brake haunch length.


2015 ◽  
Vol 35 (suppl_1) ◽  
Author(s):  
Adam R Wheeler ◽  
Daniel E Kendrick ◽  
Matthew T Allemang ◽  
Andre F Gosling ◽  
Anil Nagavalli ◽  
...  

Objective: Endoscopic vein harvest for lower extremity arterial bypass technique has been questioned due to concern for endothelial damage during procurement. We sought to compare NO mediated endothelial dependent relaxation (EDR) in vein segments harvested with open surgical (OH) versus endoscopic (EH) techniques. Methods: Saphenous vein segments were harvested for lower extremity bypass. 3-4mm vein rings were mounted on force transducers. Segments were mounted in 37° oxygenated Krebs solution and maximally contracted using KCl. NE was used to achieve submaximal contraction. EDR was determined using increasing concentrations of bradykinin (BDK). Endothelial independent relaxation was confirmed using sodium nitroprusside. Two-way ANOVA was used to analyze differences between harvest techniques across BDK concentration. Student t-test was used to examine nitrite levels in each cohort. Results: Vein segments harvested from patients (n=13) led to 28 rings (11 rings; 5 patients EH v. 17;8 OH). Both cohorts achieved moderate relaxation to maximal BDK concentration, [10 -6 M]; (49.5% EH vs. 40.55%, OH, P = .270). Analysis by two way ANOVA for mean % relaxation for BDK concentration [10 -11 - 10 -6 M] showed improved EDR in EH samples compared to OH (P =.029). Mean nitrite tissue bath concentration measurements post-BDK were 279 nM (EH) v. 194 nM (OH) (P = .264). Histology and IHC confirmed intact endothelium by morphometric analysis and CD31 staining. Conclusion: Endothelial function is preserved when utilizing endoscopic harvesting techniques. The advantages of minimally invasive vein procurement for lower extremity bypass can be obtained without concern for damaging venous endothelium.


2005 ◽  
Vol 19 (5) ◽  
pp. 495-502 ◽  
Author(s):  
Michel R. Corboz ◽  
Maria A. Rivelli ◽  
Lori Varty ◽  
Jennifer Mutter ◽  
Mark Cartwright ◽  
...  

Background Functional α1- and α2-adrenoreceptor subtype pharmacology was characterized in an in vitro human nasal mucosa contractile bioassay. Methods Nasal mucosa was obtained from 49 donor patients and mucosal strips were placed in chambers filled with Krebs–Ringer solution and attached to isometric force transducers. Results Nonselective α-adrenoreceptor agonists epinephrine, norepinephrine, and oxymetazoline produced concentration-dependent contractions of isolated human nasal mucosa (pD2= 5.2, 4.9, and 6.5, respectively). The α2-adrenoreceptor agonist BHT-920 (10 μM)–induced contractions were blocked by yohimbine (0.01–1 μM) and prazosin (0.01–1 μM) inhibited the contractile response to the α1-adrenoreceptor agonist phenylephrine (10 μM). Histological analysis showed that phenylephrine and BHT-920 differentially contracted the arteries and veins of human nasal mucosa, respectively. Conclusion Our results indicate that functional α1- and α2-adrenoceptors are present and functional in human nasal mucosa. The a 2-adrenoceptors display a predominant role in contracting the veins and the α1-adrenoceptors appear to preferentially constrict the human nasal arteries.


2017 ◽  
Vol 50 (2) ◽  
pp. 77-96
Author(s):  
Juho Sormunen

One difficulty in the design of the load bearing components of mobile machines is the transient and non-linear nature of the loads acting on them. A common method for tracking these loads is to use strain gauges and force transducers on a physical test machine. An alternative method for determining the transient loads by means of a mathematical model that intends to describe the response of a John Deere 1010E forwarder as it crosses a test track is utilized in this study. The model is based on finite element method and it is solved using explicit time integration and LS-DYNA® software. As a result of this study a model capable of replicating the real world with a reasonable accuracy was obtained. The forces acting on tires, which can be considered the most important results of this work, can be used as boundary conditions in consequent analyses, such as fatigue simulation.


2016 ◽  
Author(s):  
George Benedek ◽  
Alfred H. Casparay

2010 ◽  
Vol 298 (4) ◽  
pp. R1125-R1135 ◽  
Author(s):  
Yoshitaka Toyomasu ◽  
Erito Mochiki ◽  
Mitsuhiro Yanai ◽  
Kyoichi Ogata ◽  
Yuichi Tabe ◽  
...  

Monosodium l-glutamate (MSG) is a substance known to produce the umami taste. Recent studies indicate that MSG also stimulates a variety of activities in the gastrointestinal tract through its receptor in the gut, but no study has reported the activity in conscious large experimental animals. The aim of our study was to investigate whether direct intragastric MSG stimulates gut motility and to identify the mechanism in conscious dogs. Contractile response to intraluminal injection of MSG was studied in the fed and fasted states by means of chronically implanted force transducers. MSG (5, 15, 45, and 90 mM/kg) dissolved in water was injected into the stomach and duodenum in normal and vagotomized dogs. MSG solution was administered into the stomach before feeding, and gastric emptying was evaluated. Several inhibitors of gastrointestinal motility (atropine, hexamethonium, and granisetron) were injected intravenously before MSG administration to the stomach. The effect of MSG was investigated in Pavlov (vagally innervated corpus pouch), Heidenhain (vagally denervated corpus pouch), and antral pouch (vagally innervated) dogs. Upper gut motility was significantly increased by intragastric MSG but not significantly stimulated by intraduodenal MSG. Intragastric MSG (45 mM/kg) stimulated postprandial motility and accelerated gastric emptying. MSG-induced contractions were inhibited by truncal vagotomy, atropine, hexamethonium, and granisetron. Gut motility was increased by intrapouch injection of MSG in the Pavlov pouch, but it was not affected in the Heidenhain or antral pouch dogs. We conclude that intragastric MSG stimulates upper gut motility and accelerates gastric emptying. The sensory structure of MSG is present in the gastric corpus, and the signal is mediated by the vagus nerve.


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