Environmental Toxicants and Carcinogenicity: Role of Oxidative Stress

2021 ◽  
pp. 1-13
Author(s):  
Sanjay Saini ◽  
Jagdish Gopal Paithankar ◽  
Anurag Sharma ◽  
Debapratim Kar Chowdhuri
Keyword(s):  
Oxidative Stress ◽  
Environmental Toxicants

Environmental toxicants, oxidative stress and health adversities: interventions of phytochemicals

2021 ◽  
Author(s):  
Shiwangi Dwivedi ◽  
Sharanya Kushalan ◽  
Jagdish Gopal Paithankar ◽  
Leonard Clinton D’Souza ◽  
Smitha Hegde ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Free Radical ◽  
Common Factor ◽  
Radical Scavenging ◽  
Environmental Toxicology ◽  
Present Review ◽  
In Vivo Studies ◽  
Environmental Toxicants ◽  
Environmental Chemical

Abstract Objectives Oxidative stress is the most common factor mediating environmental chemical-induced health adversities. Recently, an exponential rise in the use of phytochemicals as an alternative therapeutics against oxidative stress-mediated diseases has been documented. Due to their free radical quenching property, plant-derived natural products have gained substantial attention as a therapeutic agent in environmental toxicology. The present review aimed to describe the therapeutic role of phytochemicals in mitigating environmental toxicant-mediated sub-cellular and organ toxicities via controlling cellular antioxidant response. Methods The present review has covered the recently related studies, mainly focussing on the free radical scavenging role of phytochemicals in environmental toxicology. Key findings In vitro and in vivo studies have reported that supplementation of antioxidant-rich compounds can ameliorate the toxicant-induced oxidative stress, thereby improving the health conditions. Improving the cellular antioxidant pool has been considered as a mode of action of phytochemicals. However, the other cellular targets of phytochemicals remain uncertain. Conclusions Knowing the therapeutic value of phytochemicals to mitigate the chemical-induced toxicity is an initial stage; mechanistic understanding needs to decipher for development as therapeutics. Moreover, examining the efficacy of phytochemicals against mixer toxicity and identifying the bioactive molecule are major challenges in the field.

792: Role of Oxidative Stress in Tumorigenic Potential of Bladder Cancer Cells

2005 ◽  
Vol 173 (4S) ◽  
pp. 214-215 ◽  
Author(s):  
Daniel Cho ◽  
Xiao Fang Ha ◽  
J. Andre Melendez ◽  
Louis J. Giorgi ◽  
Badar M. Mian
Keyword(s):  
Oxidative Stress ◽  
Bladder Cancer ◽  
Cancer Cells ◽  
Tumorigenic Potential ◽  
Bladder Cancer Cells

The role of oxidative stress in pathogenesis of posttraumatic stress disorder in a contingent of international operations

2011 ◽  
Author(s):  
V. V. Voicehovskis ◽  
G. Ancane ◽  
T. Ivascenko ◽  
J. Micans ◽  
A. Skesters ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Posttraumatic Stress Disorder ◽  
Posttraumatic Stress ◽  
Stress Disorder ◽  
International Operations

The Role of Oxidative Stress and Antioxidants in Diabetes Mellitus

2017 ◽  
Vol 1 (1) ◽  
Author(s):  
Ayşe Ceylan HAMAMCIOĞLU
Keyword(s):  
Oxidative Stress ◽  
Diabetes Mellitus

Oxidative stress and role of antioxidants in normal and abnormal sperm function

10.2741/a146 ◽  
1996 ◽  
Vol 1 (5) ◽  
pp. e78-86 ◽  
Author(s):  
S. C Sikka
Keyword(s):  
Oxidative Stress ◽  
Sperm Function ◽  
Abnormal Sperm

Role of Kupffer cells in the ethanol-induced oxidative stress in the liver

10.2741/a455 ◽  
1999 ◽  
Vol 4 (4) ◽  
pp. d589-595 ◽  
Author(s):  
Abraham P Bautista
Keyword(s):  
Oxidative Stress ◽  
Kupffer Cells
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