Dietary carbohydrate utilization in cod (Gadus morhua): metabolic responses to feeding and fasting

1993 ◽  
Vol 10 (6) ◽  
pp. 455-463 ◽  
Author(s):  
Gro-Ingunn Hemre ◽  
�yvind Lie ◽  
Anne Sundby
Author(s):  
Yanpeng Zhang ◽  
Xu-fang Liang ◽  
Shan He ◽  
Jie Wang ◽  
Ling Li ◽  
...  

2019 ◽  
Vol 91 (4) ◽  
Author(s):  
DANIEL OKAMURA ◽  
RODRIGO FORTES-SILVA ◽  
RENAN R. PAULINO ◽  
FELIPE G. DE ARAÚJO ◽  
DIEGO V. DA COSTA ◽  
...  

Author(s):  
Ed A. Maunder ◽  
Helen E. Bradley ◽  
Colleen S. Deane ◽  
Adrian B. Hodgson ◽  
Michael Jones ◽  
...  

Altering dietary carbohydrate (CHO) intake modulates fuel utilization during exercise. However, there has been no systematic evaluation of metabolic responses to graded changes in short-term (< 1 week) dietary CHO intake. Thirteen active men performed interval running exercise combined with isocaloric diets over 3 days before evaluation of metabolic responses to 60-min running at 65% V̇O2max on three occasions. Diets contained lower (LOW, 2.40 ± 0.66 g CHO.kg-1.d-1, 21.3 ± 0.5% of energy intake [EI]), moderate (MOD, 4.98 ± 1.31 g CHO.kg-1.d-1, 46.3 ± 0.7% EI), or higher (HIGH, 6.48 ± 1.56 g CHO.kg-1.d-1, 60.5 ± 1.6% EI) CHO. Pre-exercise muscle glycogen content was lower in LOW (54.3 ± 26.4 mmol.kg-1 wet weight [ww]) compared to MOD (82.6 ± 18.8 mmol.kg-1 ww) and HIGH (80.4 ± 26.0 mmol.kg-1 ww, P<0.001; MOD vs. HIGH, P=0.85). Whole-body substrate oxidation, systemic responses, and muscle substrate utilization during exercise indicated increased fat and decreased CHO metabolism in LOW (RER: 0.81 ± 0.01) compared to MOD (RER 0.86 ± 0.01, P = 0.0005) and HIGH (RER: 0.88 ± 0.01, P < 0.0001; MOD vs. HIGH, P=0.14). Higher basal muscle expression of genes encoding proteins implicated in fat utilization was observed in LOW. In conclusion, muscle glycogen availability and subsequent metabolic responses to exercise were resistant to increases in dietary CHO intake from ~5.0 to ~6.5 g CHO.kg-1.d-1 (46% to 61% EI), while muscle glycogen, gene expression and metabolic responses were sensitive to more marked reductions in CHO intake (~2.4 g CHO.kg-1.d-1, ~21% EI).


2008 ◽  
Vol 72 (4) ◽  
pp. 899-916 ◽  
Author(s):  
J. C. Pérez-Casanova ◽  
L. O. B. Afonso ◽  
S. C. Johnson ◽  
S. Currie ◽  
A. K. Gamperl

2000 ◽  
Vol 278 (5) ◽  
pp. R1164-R1170 ◽  
Author(s):  
S. Panserat ◽  
F. Médale ◽  
C. Blin ◽  
J. Brèque ◽  
C. Vachot ◽  
...  

Glucokinase (GK) plays a central role in glucose homeostasis in mammals. The absence of an inducible GK has been suggested to explain the poor utilization of dietary carbohydrates in rainbow trout. In this context, we analyzed GK expression in three fish species (rainbow trout , gilthead seabream, and common carp) known to differ in regard to their dietary carbohydrate tolerance. Fish were fed for 10 wk with either a diet containing a high level of digestible starch (>20%) or a diet totally deprived of starch. Our data demonstrate an induction of GK gene expression and GK activity by dietary carbohydrates in all three species. These studies strongly suggest that low dietary carbohydrate utilization in rainbow trout is not due to the absence of inducible hepatic GK as previously suggested. Interestingly, we also observed a significantly lower GK expression in common carp (a glucose-tolerant fish) than in rainbow trout and gilthead seabream, which are generally considered as glucose intolerant. These data suggest that other biochemical mechanisms are implicated in the inability of rainbow trout and gilthead seabream to control blood glucose closely.


Sign in / Sign up

Export Citation Format

Share Document