Nutritional and immunological investigations in head and neck cancer patients before and after therapy

1985 ◽  
Vol 242 (2) ◽  
pp. 149-153 ◽  
Author(s):  
H. Picker ◽  
E. Bichler
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Before And After

NUTRITION ASSESSMENT IN HEAD AND NECK CANCER PATIENTS PRE and POST CHEMORADIOTHERAPY.

2019 ◽  
Vol 2 (2) ◽  
Author(s):  
Piyush Kumar ◽  
Bhavya P Pateneedi ◽  
Dharam P Singh ◽  
Arvind K Chauhan
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Nutritional Risk ◽  
Total Leukocyte Count ◽  
Risk Indicator ◽  
Anthropometric Parameters ◽  
Skin Fold Thickness ◽  
Before And After

INTRODUCTION: Head and neck cancer patients are frequently malnourished at the time of diagnosis and prior to the beginning of treatment. Deterioration of the nutritional status results in an increase in chemo radiotherapy related toxicity and this may increase the prolonged treatment time, which has been associated with poor clinical outcome. The present study aims to do nutritional assessment before and after chemo radiotherapy in head and neck cancer patients. MATERIAL AND METHODS: The present study was undertaken at the Department of Radiation Oncology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly. In this study, 50 patients of Head and neck tumours were enrolled and their nutrition was assessed before and after chemoradiotherapy. Nutrition assessment was done using different laboratory parameters like haemoglobin, total leukocyte count, blood urea, serum creatinine and serum bilirubin. Anthropometric parameters used are Body mass index, Skin fold thickness, and Mid-arm circumference. Nutritional risk indicator and PG-SGA score is measured before and after chemoradiotherapy. All the parameters were assessed and analysed using different statistical tests- Chi-square test, Fisher Exact test and paired t test.RESULTS: Haemoglobin decrease was statistically significant during treatment (p less than 0.001) and the decrease in total leukocyte count during treatment was showing trend towards significance (p value-0.056). There was deterioration in other parameters like blood urea, serum creatinine and serum bilirubin but was not statistically significant. Anthropometric parameters- Body mass index, mid-arm circumference and skin fold thickness and percent body fat showed a significant change (p less than 0.00001). Nutritional risk indicator and PG-SGA class has decreased for majority of patients during treatment, the change is statistically significant (p less than 0.00001 and p=0.0251) respectively.CONCLUSION: The nutrition has important role to play in the management of head and neck cancers by chemo radiotherapy. It helps to reduce the complications and improve the tolerance of chemo radiotherapy, thus avoiding treatment breaks which may lead to failure of treatment.

Improvement of a Delayed Swallowing Reflex Following Treatment for Advanced Head and Neck Cancer

2020 ◽  
Author(s):  
Akira Ohkoshi ◽  
Kengo Kato ◽  
Takenori Ogawa ◽  
Ayako Nakanome ◽  
Ryo Ishii ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Retrospective Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Advanced Head ◽  
Silent Aspiration ◽  
Swallowing Function ◽  
Before And After ◽  
Swallowing Reflex

Abstract Background: The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing voluntary swallowing function before and after treatment, few studies have focused on the latency of the swallowing reflex, which is a risk factor for pneumonia due to silent aspiration. The aim of this retrospective study was to clarify the changes in the latency of the swallowing reflex before and after treatment. Methods: The latency of the swallowing reflex was quantified using the time from the injection of 1 ml of distilled water into the pharynx through a nasal catheter to the onset of swallowing. Results: The latency time of the swallowing reflex was significantly decreased 3 months after treatment compared to before treatment. A significant reduction was also observed in patients with pharyngeal cancer who underwent chemoradiation therapy. Conclusions: This retrospective study showed that a delayed swallowing reflex improved with treatment in advanced head and neck cancer patients.

Mouth Care for Head and Neck Cancer Patients – a Dental Hygienist's Perspective

Dental Update ◽  
2020 ◽  
Vol 47 (10) ◽  
pp. 867-870
Author(s):  
Jocelyn Harding
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Clear Understanding ◽  
Proactive Approach ◽  
Post Surgery ◽  
Mouth Care ◽  
Dental Practitioners ◽  
Before And After

A proactive approach to the mouth care of head and neck cancer patients, from their initial visit to their discharge, is vitally important. This area of care is complicated by many factors, of which some patients will not be aware when they start their difficult journey. This article is written to give the reader an insight into the dental hygienist's perspective of mouth care before, during and after treatment and then graduating the patient back into primary care. The treatment for each head and neck cancer patient is varied, therefore the process of healing post-surgery and therapy can be complicated. Balancing patient's expectations before and after diagnosis is a difficult task and may be impossible to predict, which makes this area of care complicated and involved for the dental hygienist. CPD/Clinical Relevance: The diagnosis and treatment of head and neck cancer takes place in hospitals and involves a team of clinicians, including dental hygienists. Once patients treated for such cancers return to general dental practice, it is essential that general dental practitioners (GDPs) and their teams have a clear understanding of how they have been treated and how GDPs and their teams can contribute to the patients' aftercare.

scholarly journals Improvement of a Delayed Swallowing Reflex with Treatment in Advanced Head and Neck Cancer Patients

2020 ◽  
Author(s):  
Akira Ohkoshi ◽  
Kengo Kato ◽  
Takenori Ogawa ◽  
Ayako Nakanome ◽  
Ryo Ishii ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Retrospective Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Advanced Head ◽  
Pharyngeal Cancer ◽  
Swallowing Function ◽  
Before And After ◽  
Swallowing Reflex

Abstract Background The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing swallowing function before and after treatment, few studies have focused on the latency of the swallowing reflex. The aim of this retrospective study was to clarify the changes in the latency of the swallowing reflex before and after treatment. Methods The latency of the swallowing reflex was quantified using the time from the injection of 1 ml of distilled water into the pharynx through a nasal catheter to the onset of swallowing. Results The latency time of the swallowing reflex was significantly decreased 3 months after treatment compared to before treatment. Significant reduction was also observed in patients with pharyngeal cancer who underwent chemoradiation therapy. Conclusions This retrospective study showed that a delayed swallowing reflex improved with treatment in advanced head and neck cancer patients.

scholarly journals Improvement of a Delayed Swallowing Reflex with Treatment in Advanced Head and Neck Cancer Patients

2020 ◽  
Author(s):  
Akira Ohkoshi ◽  
Kengo Kato ◽  
Takenori Ogawa ◽  
Ayako Nakanome ◽  
Ryo Ishii ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Retrospective Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
University Hospital ◽  
Advanced Head ◽  
Swallowing Function ◽  
Before And After ◽  
Swallowing Reflex

Abstract Background: The latency of the swallowing reflex is an important factor causing dysphagia in head and neck cancer patients. Although there are many reports comparing voluntary swallowing function before and after treatment, few studies have focused on the latency of the swallowing reflex, which is a risk factor for pneumonia due to silent aspiration. The aim of this retrospective study was to clarify the changes in the latency of the swallowing reflex before and after treatment.Methods: The latency of the swallowing reflex was quantified using the time from the injection of 1 ml of distilled water into the pharynx through a nasal catheter to the onset of swallowing. Results: The latency time of the swallowing reflex was significantly decreased 3 months after treatment compared to before treatment. A significant reduction was also observed in patients with pharyngeal cancer who underwent chemoradiation therapy.Conclusions: This retrospective study showed that a delayed swallowing reflex improved with treatment in advanced head and neck cancer patients.Trial registration number: The Institutional Review Board of Tohoku University Hospital (Number 2014-1-274).

scholarly journals Metabolic Profiles of Whole Serum and Serum-Derived Exosomes Are Different in Head and Neck Cancer Patients Treated by Radiotherapy

2020 ◽  
Vol 10 (4) ◽  
pp. 229
Author(s):  
Anna Wojakowska ◽  
Aneta Zebrowska ◽  
Agata Skowronek ◽  
Tomasz Rutkowski ◽  
Krzysztof Polanski ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Energy Metabolism ◽  
Pilot Study ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Gas Chromatography Mass Spectrometry ◽  
Serum Samples ◽  
Before And After ◽  
And Control

Background: In general, the serum metabolome reflects the patient’s body response to both disease state and implemented treatment. Though serum-derived exosomes are an emerging type of liquid biopsy, the metabolite content of these vesicles remains under researched. The aim of this pilot study was to compare the metabolite profiles of the whole serum and serum-derived exosomes in the context of differences between cancer patients and healthy controls as well as patients’ response to radiotherapy (RT). Methods: Serum samples were collected from 10 healthy volunteers and 10 patients with head and neck cancer before and after RT. Metabolites extracted from serum and exosomes were analyzed by the gas chromatography–mass spectrometry (GC–MS). Results: An untargeted GC–MS-based approach identified 182 and 46 metabolites in serum and exosomes, respectively. Metabolites that differentiated cancer and control samples, either serum or exosomes, were associated with energy metabolism. Serum metabolites affected by RT were associated with the metabolism of amino acids, sugars, lipids, and nucleotides. Conclusions: cancer-related features of energy metabolism could be detected in both types of specimens. On the other hand, in contrast to RT-induced changes observed in serum metabolome, this pilot study did not reveal a specific radiation-related pattern of exosome metabolites.

scholarly journals Calcified carotid artery atheromas on panoramic radiographs of head and neck cancer patients before and after radiotherapy

2017 ◽  
pp. 0-0
Author(s):  
RL. Markman ◽  
KG. Conceicao-Vasconcelos ◽  
TB. Brandao ◽  
AC. Prado-Ribeiro ◽  
AR. Santos-Silva ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Carotid Artery ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Panoramic Radiographs ◽  
Before And After

A turning point: Head and neck cancer patients’ exercise preferences and barriers before and after participation in an exercise intervention

2018 ◽  
Vol 27 (2) ◽  
pp. e12826 ◽  
Author(s):  
C. Jackson ◽  
A.J. Dowd ◽  
L.C. Capozzi ◽  
W. Bridel ◽  
H.Y. Lau ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Turning Point ◽  
Exercise Intervention ◽  
Before And After
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