Effects of intrathecally administered pentobarbital and naloxone on the activity evoked in ascending axons of the rat spinal cord by stimulation of afferent A and C fibres

1983 ◽  
Vol 323 (3) ◽  
pp. 211-216 ◽  
Author(s):  
G�nther Bernatzky ◽  
Takayuki Doi ◽  
Ilmar Jurna
Keyword(s):  
Spinal Cord ◽  
Rat Spinal Cord ◽  
Stimulation Of

Recovery of spinal cord function induced by direct current stimulation of the injured rat spinal cord

Neurosurgery ◽  
1987 ◽  
Vol 20 (6) ◽  
pp. 878???84 ◽  
Author(s):  
M C Wallace ◽  
C H Tator ◽  
I Piper
Keyword(s):  
Spinal Cord ◽  
Direct Current ◽  
Rat Spinal Cord ◽  
Direct Current Stimulation ◽  
Spinal Cord Function ◽  
Stimulation Of

Intracellular recording from visually identified motoneurons in rat spinal cord slices

1978 ◽  
Vol 202 (1148) ◽  
pp. 417-421 ◽  
Keyword(s):  
Spinal Cord ◽  
Neuronal Activity ◽  
Intracellular Recording ◽  
Action Potentials ◽  
Intracellular Recordings ◽  
Rat Spinal Cord ◽  
Local Sensitivity ◽  
New Born ◽  
Intracellular Stimulation ◽  
Stimulation Of

Motoneurons were directly visualized with Nomarski optics in slices prepared from new born rat spinal cord. Intracellular recordings from these neurons showed spontaneous potentials, probably triggered by inter-neuronal activity. Action potentials could also be evoked by direct intracellular stimulation of the motoneurons. Iontophoretically applied L-glutamate caused a fast depolarization of the motoneuronal membrane. Considerable differences in local sensitivity to L-glutamate were found on the surface of the motoneuron.

GABA-Mediated Trophic Effect on Oligodendrocytes Requires Na-K-2Cl Cotransport Activity

2003 ◽  
Vol 90 (2) ◽  
pp. 1257-1265 ◽  
Author(s):  
Hao Wang ◽  
Yiping Yan ◽  
Douglas B. Kintner ◽  
Christian Lytle ◽  
Dandan Sun
Keyword(s):  
Spinal Cord ◽  
Growth Factors ◽  
Basic Protein ◽  
Rat Spinal Cord ◽  
Animal Cells ◽  
Cell Shrinkage ◽  
Trophic Effect ◽  
Intracellular Ca ◽  
Electrochemical Equilibrium ◽  
Stimulation Of

The Na-K-2Cl cotransporter isoform1 (NKCC1) is present in many animal cells where it plays prominent roles in regulating cell volume and maintaining intracellular Cl– concentration ([Cl–]i) above electrochemical equilibrium. We show here that NKCC1 is present and active in cultured oligodendrocytes. Expression of NKCC1 in the rat spinal cord increased during development from postnatal day 6 through 21 in parallel with that of myelin basic protein. In cultured oligodendrocytes, 39% of the total K+ (86Rb+) influx represented NKCC1 activity. Activation of GABAA receptors with muscimol produced a reduction in intracellular Cl– content, cell shrinkage, and a stimulation of NKCC1 activity. Muscimol also triggered an increase in intracellular Ca2+, which depended on NKCC1 activity. Survival of oligodendrocytes following withdrawal of growth factors was enhanced by muscimol and this effect also required NKCC1 activity. Our results suggest that NKCC1 functions in oligodendrocytes to maintain [Cl–]i above electrochemical equilibrium and that NKCC1 is required for GABAergic trophic effects.

scholarly journals A micro-LED implant and technique for optogenetic stimulation of the rat spinal cord

2021 ◽  
Vol 335 ◽  
pp. 113480
Author(s):  
S.E. Mondello ◽  
B.D. Pedigo ◽  
M.D. Sunshine ◽  
A.E. Fischedick ◽  
P.J. Horner ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Rat Spinal Cord ◽  
Optogenetic Stimulation ◽  
Stimulation Of

Electrical stimulation of cortex improves corticospinal tract tracing in rat spinal cord using manganese-enhanced MRI

2006 ◽  
Vol 156 (1-2) ◽  
pp. 17-22 ◽  
Author(s):  
Mehmet Bilgen ◽  
Warner Peng ◽  
Baraa Al-Hafez ◽  
Numa Dancause ◽  
Yong-Yue He ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Electrical Stimulation ◽  
Corticospinal Tract ◽  
Rat Spinal Cord ◽  
Tract Tracing ◽  
Enhanced Mri ◽  
Manganese Enhanced Mri ◽  
Stimulation Of
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