Role of vasopressin- and oxytocinergic cells of the magnicellular nuclei of the rat hypothalamus in thyroid gland regulation after administration of thyroliberin

1989 ◽  
Vol 19 (6) ◽  
pp. 503-506
Author(s):  
I. A. Krasnovskaya ◽  
G. V. Dityateva ◽  
A. L. Polenov
2018 ◽  
Vol 22 (4) ◽  
pp. 760-765
Author(s):  
О.І. Tiron

Despite the important role of the thyroid gland in regulating the functions of the body, the gland is quite sensitive to the adverse effects of various factors on the body. The purpose of the work is to analyze modern sources of scientific literature devoted to the study of the influence of exo- and endogenous factors on the morpho-functional properties of the thyroid gland. Literary data on the influence on the thyroid gland of various environmental chemicals, insufficient or excessive consumption of iodine and selenium, vitamin D deficiency, exposure to pharmaceuticals, smoking, environmental temperature, irradiation, infections, stress, as well as factors of the internal environment, such as atherosclerosis and pregnancy. There are a small number of modern scientific studies concerning the influence on the structure and function of the thyroid gland consequences of thermal injury of the skin.


1969 ◽  
Vol 216 (4) ◽  
pp. 939-945 ◽  
Author(s):  
LV Avioli ◽  
SJ Birge ◽  
S Scott ◽  
W Shieber
Keyword(s):  

1976 ◽  
Vol 69 (3) ◽  
pp. 421-425 ◽  
Author(s):  
B. N. PANDEY ◽  
J. S. D. MUNSHI

SUMMARY Studies on cyclic activity of the thyroid and seasonal variations in oxygen consumption (V̇o2) under experimental conditions in which surfacing was either allowed or prevented were made in H. fossilis to try to establish a relationship between these measures and to ascertain the possible role of the thyroid in the regulation of metabolic rate. A good correlation was found between the activity of the thyroid and V̇o2 in this species. This finding was further confirmed by the administration of l-thyroxine or thiouracil to this fish. The thyroxine-and thiouracil-treated animals showed significantly higher (P < 0·05) and lower (P < 0·01) rates of V̇o2 respectively, thus indicating the probable role of the thyroid in the regulation of metabolic rate.


1968 ◽  
Vol 57 (3) ◽  
pp. 363-373 ◽  
Author(s):  
J. N. Panda ◽  
C. W. Turner ◽  
Mary Powell

ABSTRACT The fact that melatonin, a pineal substance, causes a depression in thyroid function of prepuberal rats has been reported. A possible site of this action on the thyroid gland has been studied by estimating the TSH content of blood and hypophysis in rats from 35 days to 65 days of age. Haemagglutination-inhibition technique has been used to assay very small amounts of TSH in plasma. Rats receiving 100 μg of melatonin daily for 10 days were sacrificed at 35, 45, 55 and 65 days of age. The mean thyroid weight of each group was markedly higher than that of the corresponding controls. The plasma TSH/ml level was higher in experimental groups, with a marked decrease (0.10 > P > 0.05) in TSH/mg of hypophysis (wet), especially at 45 and 55 days of age. Rats similarly treated with 400 μg/100 g body weight of tapazole daily for 10 days and sacrificed at 45 and 55 days of age showed higher plasma and lower hypophyseal TSH levels than the controls and the results were comparable to those of the melatonin treated groups. The dry-fat-free tissue of the thyroid glands of the melatonin treated groups were higher than the corresponding controls and their DNA content was significantly higher (0.050 > P > 0.025) also, indicating hyperplasia and hypertrophy of the thyroid glands resulting from the action of melatonin. The histological picture of the melatonin treated animals showed goitrogenic effect. It may be concluded from these data that melatonin exerts its regulatory effect on TSH secretion directly acting on the thyroid gland and in some way inhibiting thyroid hormone synthesis or release.


Sign in / Sign up

Export Citation Format

Share Document