Definition of urinary tract infection and assessment of efficacy in drug trials — A laboratory perspective

Infection ◽  
1992 ◽  
Vol 20 (S3) ◽  
pp. S155-S156 ◽  
Author(s):  
R. C. B. Slack
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Drug Trials ◽  
Definition Of

scholarly journals Diagnosis of Urinary Tract Infection in the Neuropathic Bladder: Changing the Paradigm to Include the Microbiome

2019 ◽  
Vol 25 (3) ◽  
pp. 222-227 ◽  
Author(s):  
Catherine S. Forster ◽  
Hans Pohl
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Clinical Management ◽  
Significant Variation ◽  
Asymptomatic Bacteriuria ◽  
Specific Term ◽  
Variation In Care ◽  
Urinary Microbiome ◽  
Definition Of

Bacteriuria, a non-specific term that refers to the presence of bacteria in the urine, is common in people with neuropathic bladders. However, accurately determining when bacteriuria represents a urinary tract infection (UTI) as opposed to asymptomatic bacteriuria is difficult. There is currently no widely accepted definition of what constitutes a UTI in people with neuropathic bladders. As a result, there is significant variation in care, which likely leads to unnecessary use of antibiotics for bacteriuria. To improve the clinical management of people with neuropathic bladders, it is important to be able to accurately diagnose and treat UTIs. In this article, we review the difficulties associated with accurately diagnosing UTIs and then review proposed definitions. Finally, we discuss the emerging literature of the urinary microbiome and how this may assist in accurately diagnosing UTIs in people with neuropathic bladders.

scholarly journals Symptom-based diagnosis of overactive bladder: an overview

2013 ◽  
Vol 5 (5-S2) ◽  
pp. 135
Author(s):  
Alan Wein
Keyword(s):  
Bladder Cancer ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Overactive Bladder ◽  
Clinical Diagnosis ◽  
Urge Incontinence ◽  
Subjective Assessment ◽  
Current Definition ◽  
Definition Of

The current definition of overactive bladder (OAB) is “urgency,with or without urge incontinence, usually with frequency andnocturia in the absence of an underlying metabolic or pathologiccondition.” Urgency, in turn, is defined as a “sudden, compellingdesire to pass urine that is difficult to defer.” While these definitionsprovide the framework for making a clinical diagnosis ofOAB, they rely on subjective assessment of the symptoms by thepatient. As well, the symptoms of OAB can be similar to thoseseen in other conditions, such as urinary tract infection, benignprostatic enlargement and bladder cancer. These other potentialdiagnoses should be ruled out in a noninvasive manner beforemaking a diagnosis of OAB.

scholarly journals Catheter-Associated Urinary Tract Infection Does Changing the Definition Change Quality?

2013 ◽  
Vol 34 (3) ◽  
pp. 313-315 ◽  
Author(s):  
Matthew J. Press ◽  
Joshua P. Metlay
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Disease Control ◽  
Asymptomatic Bacteriuria ◽  
Longitudinal Measurements ◽  
Control And Prevention ◽  
Centers For Disease Control ◽  
Definition Of

The Centers for Disease Control and Prevention (CDC) recently narrowed its definition of catheter-associated urinary tract infection (CAUTI) to exclude asymptomatic bacteriuria. Although CAUTI rates decreased after the definition was changed, rates of related measures remained relatively stagnant, which indicates that longitudinal measurements of CAUTI may be misleading and that the change in definition did not itself impact care.

Impact and Limitations of the 2015 National Health and Safety Network Case Definition on Catheter-Associated Urinary Tract Infection Rates

2016 ◽  
Vol 38 (2) ◽  
pp. 239-241 ◽  
Author(s):  
Ana Cecilia Bardossy ◽  
Rachna Jayaprakash ◽  
Anjali C. Alangaden ◽  
Patricia Starr ◽  
Odaliz Abreu-Lanfranco ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Intensive Care ◽  
Urinary Tract ◽  
Tract Infection ◽  
Intensive Care Units ◽  
National Health ◽  
Health And Safety ◽  
Case Definition ◽  
Infection Rates ◽  
Definition Of

Application of the new 2015 NHSN definition of catheter-associated urinary tract infection (CAUTI) in intensive care units reduced CAUTI rates by ~50%, primarily due to exclusion of candiduria. This significant reduction in CAUTI rates resulting from the changes in the definition must be considered when evaluating effectiveness of CAUTI prevention programs.Infect Control Hosp Epidemiol2017;38:239–241

scholarly journals The Potential Impact of Excluding Funguria from the Surveillance Definition of Catheter-Associated Urinary Tract Infection

2015 ◽  
Vol 36 (4) ◽  
pp. 467-469 ◽  
Author(s):  
Kristen V. Dicks ◽  
Arthur W. Baker ◽  
Michael J. Durkin ◽  
Sarah S. Lewis ◽  
Rebekah W. Moehring ◽  
...  
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Medical Center ◽  
Tertiary Care ◽  
Infect Control Hosp ◽  
Tertiary Care Medical Center ◽  
Potential Impact ◽  
Definition Of ◽  
True Infection

Funguria rarely represents true infection in the urinary tract. Excluding yeast from the catheter-associated urinary tract infection (CAUTI) surveillance definition reduced CAUTI rates by nearly 25% in community hospitals and at an academic, tertiary-care medical center.Infect Control Hosp Epidemiol 2015;00(0): 1–3

scholarly journals Potential Misclassification of Urinary Tract–Related Bacteremia Upon Applying the 2015 Catheter-Associated Urinary Tract Infection Surveillance Definition From the National Healthcare Safety Network

2016 ◽  
Vol 37 (4) ◽  
pp. 469-471 ◽  
Author(s):  
M. Todd Greene ◽  
David Ratz ◽  
Jennifer Meddings ◽  
Mohamad G. Fakih ◽  
Sanjay Saint
Keyword(s):  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Urine Culture ◽  
National Healthcare Safety Network ◽  
Infection Surveillance ◽  
Colony Forming Units ◽  
Control And Prevention ◽  
Definition Of ◽  
Tract Infections

The Centers for Disease Control and Prevention recently updated the surveillance definition of catheter-associated urinary tract infection to include only urine culture bacteria of at least 1×105 colony-forming units/mL. Our findings suggest that the new surveillance definition may fail to capture clinically meaningful catheter-associated urinary tract infections.Infect. Control Hosp. Epidemiol. 2016;37(4):469–471

scholarly journals MP26-01 INCONSISTENCY IN THE DEFINITION OF URINARY TRACT INFECTION IN THE SPINAL CORD INJURY POPULATION: A SYSTEMATIC REVIEW

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Laura L. Giusto ◽  
Yahir Santiago-Lastra ◽  
Michael V. Hughes ◽  
Mark MacEachern ◽  
Anne P. Cameron
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Urinary Tract Infection ◽  
Urinary Tract ◽  
Tract Infection ◽  
Cord Injury ◽  
Definition Of
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