Relationship of nuclear magnetic resonance examinations to clinical data, cerebrospinal fluid findings and visual evoked potentials in multiple sclerosis

1987 ◽  
Vol 10 (3) ◽  
pp. 201-208 ◽  
Author(s):  
Detlev Uhlenbrock ◽  
Eva Herbe ◽  
Michael Haupts
Keyword(s):  
Multiple Sclerosis ◽  
Nuclear Magnetic Resonance ◽  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Evoked Potentials ◽  
Clinical Data ◽  
Visual Evoked Potentials ◽  
Relationship Of ◽  
Nuclear Magnetic ◽  
Visual Evoked

The Early Diagnosis of Multiple Sclerosis

1980 ◽  
Vol 25 (1) ◽  
pp. 58-62
Author(s):  
B. Ashworth
Keyword(s):  
Multiple Sclerosis ◽  
Cerebrospinal Fluid ◽  
Early Diagnosis ◽  
Optic Neuritis ◽  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Spastic Paraparesis ◽  
Psychological Disorder ◽  
Electrophysiological Tests ◽  
Visual Evoked

An outline of modern views on the aetiology of multiple sclerosis is followed by a discussion of diagnosis. Examination of the cerebrospinal fluid, visual evoked potentials, and other electrophysiological tests are considered. The special problems of optic neuritis, spastic paraparesis, and psychological disorder receive more detailed attention. It is concluded that while the supplementary tests are valuable the diagnosis remains essentially clinical.

scholarly journals Nuclear Magnetic Resonance Study of Cerebrospinal Fluid From Patients With Multiple Sclerosis

1993 ◽  
Vol 20 (3) ◽  
pp. 194-198 ◽  
Author(s):  
Lynch Joanna ◽  
Peeling James ◽  
Auty Anthony ◽  
R. Sutherland Garnette
Keyword(s):  
Multiple Sclerosis ◽  
Nuclear Magnetic Resonance ◽  
Cerebrospinal Fluid ◽  
Magnetic Resonance ◽  
Progressive Multiple Sclerosis ◽  
Aids Dementia Complex ◽  
Proton Nuclear Magnetic Resonance ◽  
Significant Difference ◽  
Metabolite Concentrations ◽  
Nuclear Magnetic

ABSTRACT:Proton nuclear magnetic resonance (NMR) spectroscopy was used to examine cerebrospinal fluid (CSF) from patients (n = 30) with actively progressive multiple sclerosis (MS). Metabolite concentrations obtained from the spectra were compared to those determined from the spectra of CSF from control patients (n = 27) with benign spinal disorders. No significant difference was found between the 2 groups for most constituents, including lactate, glutamine, citrate, creatine and creatinine, and glucose. Acetate levels were significantly higher in MS patients, while formate levels were significantly lower, than the controls. There were no significant differences in metabolite concentrations in CSF from early and longstanding MS patients. A peak due to an unidentified compound was found at 2.82 ppm in the spectra of CSF from patients with actively progressive MS, but not in the spectra of CSF from the controls. The peak was not found in spectra of CSF from patients with AIDS dementia complex (n = 9) or Parkinson's disease (n = 5), but it did appear in spectra of CSF from 1 patient with Jakob-Creutzfeldt disease (out of 3 examined) and from 1 patient (out of 7) with Guillan-Barré disease. The unidentified compound is volatile and, from the chemical shift of the observed NMR peak, is probably an N-methyl compound. As such, it may be an intermediate in the cholino-glycine cycle, in which an abnormality has been proposed to exist in MS patients.

Symptomatic retrochiasmal lesions in multiple sclerosis: Clinical features, visual evoked potentials, and magnetic resonance imaging

Neurology ◽  
1992 ◽  
Vol 42 (1) ◽  
pp. 68-68 ◽  
Author(s):  
G. T. Plant ◽  
A. G. Kermode ◽  
G. Turano ◽  
I. F. Moseley ◽  
D. H. Miller ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Multiple Sclerosis ◽  
Magnetic Resonance ◽  
Evoked Potentials ◽  
Clinical Features ◽  
Visual Evoked Potentials ◽  
Resonance Imaging ◽  
Visual Evoked

Relationship of Visual-Evoked Potentials With Specific Symptoms of Schizotypy

2012 ◽  
Author(s):  
Jeffrey S. Bedwell ◽  
Yuri Rassovsky ◽  
Pamela Butler ◽  
Andrea Ranieri ◽  
Christopher Spencer ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Relationship Of ◽  
Specific Symptoms ◽  
Visual Evoked
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