Immunohistochemical location of HPL, SP1 and β-HCG in normal placentas of varying gestational age

1986 ◽  
Vol 239 (2) ◽  
pp. 63-74 ◽  
Author(s):  
T. Beck ◽  
G. Schweikhart ◽  
E. Stolz
Keyword(s):  
Gestational Age ◽  
Β Hcg

Could serum β-hCG levels and gestational age be the indicative factors for the prediction of the degree of trophoblastic invasion into tubal wall in unruptured ampullary pregnancies?

2012 ◽  
Vol 287 (2) ◽  
pp. 323-328 ◽  
Author(s):  
Emre Niyazi Turgut ◽  
Ebru Celik ◽  
Serdar Celik ◽  
Deniz Cemgil Arikan ◽  
Huseyin Altuntas ◽  
...  
Keyword(s):  
Gestational Age ◽  
Β Hcg

scholarly journals Prediction of small for gestational age neonates in twin pregnancies by first trimester maternal serum PAPP-A and free β-hCG

2014 ◽  
Vol 22 (3) ◽  
pp. 152-155
Author(s):  
Dilek Beker Şanlı ◽  
Kazım Kartkaya ◽  
Fezan Şahin Mutlu
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
First Trimester ◽  
Maternal Serum ◽  
Β Hcg ◽  
Twin Pregnancies

First trimester maternal serum PAPP-A, β-hCG and ADAM12 in prediction of small-for-gestational-age fetuses

2008 ◽  
Vol 28 (12) ◽  
pp. 1131-1135 ◽  
Author(s):  
Kasper Pihl ◽  
Torben Larsen ◽  
Lone Krebs ◽  
Michael Christiansen
Keyword(s):  
Gestational Age ◽  
Small For Gestational Age ◽  
First Trimester ◽  
Maternal Serum ◽  
Β Hcg

PAPP-A and free β-hCG measured prior to 10 weeks is associated with preterm delivery and small-for-gestational-age infants

2011 ◽  
Vol 31 (2) ◽  
pp. 171-175 ◽  
Author(s):  
Ida Kirkegaard ◽  
Tine Brink Henriksen ◽  
Niels Tørring ◽  
Niels Uldbjerg
Keyword(s):  
Preterm Delivery ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Β Hcg

scholarly journals Marcadores Bioquímicos do Primeiro Trimestre e Recém-Nascidos Leves para Idade Gestacional

2014 ◽  
Vol 27 (2) ◽  
pp. 191
Author(s):  
Cláudia Andrade ◽  
Joana Santos ◽  
Ana Rita Pinto ◽  
Pedro Manso ◽  
Susana Pereira
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Small For Gestational Age ◽  
Odds Ratio ◽  
Biochemical Markers ◽  
First Trimester ◽  
Control Group ◽  
Maternal Weight ◽  
Increased Risk ◽  
Β Hcg

<strong>Introduction:</strong> Several studies suggested an association between first trimester biochemical markers (PAPP-A and β- HCG) and infants below 10th percentile. Our goal was to describe this relationship of biochemical markers with small-for- gestational-age fetuses in our population.<br /><strong>Material and Methods:</strong> Retrospective analytic study of 2 035 pregnant women that underwent first-trimester screening in the period between March 2009 and September 2011. Small-for-gestational-age infants below 10th percentile were compared with control group (term newborn with birth weight above 10th percentile). Infants below 3rd percentile and control group were also compared. Multiple and logistic regression analysis were done with PAPP-A, β-HCG (multiples of the expected normal median) and demographic maternal characteristics (ethnicity, weight and smoker status).<br /><strong>Results:</strong> This study demonstrated an independent contribution of PAPP-A, maternal weight and smoker status in predicting small-for-gestational-age infants. For PAPP-A, the odds ratio for small-for-gestational age below 10th and 3rd percentile was 2.41 and 3.41, respectively (p &lt; 0.01). For β-HCG, odds ratio below 10th percentile was 1.70 (p = 0.03) and for birth weight below the 3rd percentile, the odds ratio was 3.22 (p &lt; 0.01).<br /><strong>Conclusions:</strong> Low levels of PAPP-A and β-HCG (values below 5th percentile of the study population) were associated with an increased risk of small-for-gestational-age infants in the pregnant population included in this study.

scholarly journals Study of various treatment modalities of caesarean scar pregnancy

2021 ◽  
Vol 11 (1) ◽  
pp. 217
Author(s):  
Prachi C. Meghani ◽  
Sapna R. Shah ◽  
Rupa C. Vyas ◽  
Purvi M. Parikh ◽  
Tanmay J. Chudasama
Keyword(s):  
Gestational Age ◽  
Color Doppler ◽  
Haemorrhagic Shock ◽  
Treatment Modalities ◽  
Transvaginal Sonography ◽  
Caesarean Scar ◽  
Global Rate ◽  
Ultrasound Findings ◽  
Caesarean Scar Pregnancy ◽  
Β Hcg

Background: Caesarean scar pregnancy (CSP) can be defined as the implantation of the gestational sac within the scar of a previous caesarean surgery. Incidence of CSP is 1 in 1800 pregnancies.Methods: It is a retrospective study based on clinical diagnosis and management of CSP of women who presented to the obstetrics and gynaecology department SVP hospital from January 2008 to August 2021. Total number of cases of CSP were 28. Incidence, gestational age, ultrasound findings, serum β-human chorionic gonadotropin (β-hCG) levels, flow profiles of color Doppler, and different methods of treatment were recorded. Diagnosis was confirmed by ultrasound.Results: In this study, all 28 cases of CSP considered were offered definitive management. In present study 5 cases (17.88%) showed torrential haemorrhage during dilatation and evacuation (D and E) which was treated by various methods like 1 (3.57%) Foley’s tamponade, 1 (3.57%) uterine artery embolization (UAE) and 3 (10.71%) hysterectomy. Hysterotomy was performed in 13 cases (46.42%) and (7.69%) of heterotrophic CSP (HCSP). One case (3.84%) of CSP presented at 26 weeks of gestation with haemorrhagic shock, underwent obstetric hysterectomy.Conclusions: There is a rise in the incidence of CSP because of increase in the global rate of caesarean sections and early transvaginal USG in pregnancy. Transvaginal sonography is the best diagnostic tool. Medical management can be offered when diagnosis is made at gestational age of <7 weeks. Whereas, surgical modalities have shown better results at >7 weeks of gestational age. Surgical management has an advantage of shorter follow up. 

scholarly journals Ovarian hyperstimulation syndrome in a spontaneous singleton pregnancy

2016 ◽  
Vol 14 (2) ◽  
pp. 231-234
Author(s):  
Fábio Roberto Cabar
Keyword(s):  
Gestational Age ◽  
Ovarian Hyperstimulation Syndrome ◽  
First Trimester ◽  
Thyroid Stimulating Hormone ◽  
Ovarian Hyperstimulation ◽  
Singleton Pregnancy ◽  
Free T4 ◽  
Ovarian Volume ◽  
Β Hcg ◽  
Multiple Cysts

ABSTRACT The ovarian hyperstimulation syndrome is the combination of increased ovarian volume, due to the presence of multiple cysts and vascular hyperpermeability, with subsequent hypovolemia and hemoconcentration. We report a case of spontaneous syndrome in a singleton pregnancy. This was a spontaneous pregnancy with 12 weeks of gestational age. The pregnancy was uneventful until 11 weeks of gestational age. After that, the pregnant woman complained of progressive abdominal distention associated with abdominal discomfort. She did not report other symptoms. In the first trimester, a routine ultrasonography showed enlarged ovaries, multiples cysts and ascites. Upon admission, the patient was hemodynamically stable, her serum β-hCG was 24,487mIU/mL, thyroid-stimulating hormone was 2.2µUI/mL and free T4 was 1.8ng/dL. All results were within normal parameters. However, levels of estradiol were high (10,562pg/mL). During hospitalization, she received albumin, furosemide and prophylactic dose of enoxaparin. The patient was discharged on the sixth hospital day.

RISK FACTORS OF RUPTURED ECTOPIC PREGNANCY

2016 ◽  
pp. 112-116
Author(s):  
Lam Huong Le
Keyword(s):  
Risk Factors ◽  
Ectopic Pregnancy ◽  
Gestational Age ◽  
Abdominal Ultrasound ◽  
First Trimester ◽  
Predictive Index ◽  
Cross Sectional ◽  
Increased Risk ◽  
Risk Of Rupture ◽  
Β Hcg

Background: Ectopic pregnancy is the highest mortality cause in the first trimester of pregnancy, accounted for 4 -10%. Ectopic pregnancy which has high level of β-hCG, older gestation age makes it easy to rupture and leading to several dangerous complications. Aim: To studiely the risk factors for ruptured ectopic pregnancy. Methods: A retrospective cross-sectional descriptive, including 113 patients at Hue Central Hospital who has been diagnosed and treatment of ectopic pregnancy. Results: The ruptured ectopic pregnancy group and unruptured ectopic pregnancy group has: > 35 years old accounted for 38.6% and 15.9%; The average age was 28.9 ± 5.4 and 27.8 ± 5.9; < 6 weeks gestational age accounted for 6,8% and 60,9%; 6 – 8 weeks gestational age was 52.3% and 34.8%, over 8 weeks has proportion of 40.9% 4.3%, respectively. The average βhCG concentration (IU/ml) in ruptured ectopic pregnancy group was 4423 ± 5879.9 IU/ml; βhCG > 5000 (IU/ml) accounted for 50%, in the unruptured ectopic pregnancy group was 2423 ± 3879,9 IU/ml; βhCG> 5000 (IU/ml) accounted for 5,8%. With maternal age > 35, the risk of ruptured ectopic pregnancy was higher 2.42(95% CI= 1.03-5.65). Gestational age > 8 weeks, the risk of ruptured ectopic pregnancy was higher 15.2(95% CI= 4.1- 56.1). The risk of ruptured ectopic pregnancy was higher 16.2 with βhCG (IU/ml) >5000 (95% CI= 5.0-52.3). The threshold predictive index of βhCG leading to ruptured ectopic pregnancy under the ROC curve was 0.9 of βhCG (95% CI= 1.1- 8.6). At the level 4190 (IU/ml) βhCG concentration corresponding to 88.6% sensitivity, 67.3% specificity. Conclusion: According to our study, higher βhCG levels, especially >5000 IU/ml, and higher gestational age are associated with increased risk of rupture in ectopic pregnancy. It is nessecery to monitor carefully of patients with risk factors for ruptured ectopic pregnancy for suitable treatment which lead to decrease the risk of complications. Key words: Ectopic pregnancy, abdominal ultrasound, β - hCG, complications

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