scholarly journals Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis

1994 ◽  
Vol 56 (2) ◽  
pp. 295-321 ◽  
Author(s):  
Vladimir A. Kuznetsov ◽  
Iliya A. Makalkin ◽  
Mark A. Taylor ◽  
Alan S. Perelson
1993 ◽  
Vol 03 (02) ◽  
pp. 399-404 ◽  
Author(s):  
T. SÜNNER ◽  
H. SAUERMANN

Nonlinear self-excited oscillations are usually investigated for two-dimensional models. We extend the simplest and best known of these models, the van der Pol oscillator, to a three-dimensional one and study its dynamical behaviour by methods of bifurcation analysis. We find cusps and other local codimension 2 bifurcations. A homoclinic (i.e. global) bifurcation plays an important role in the bifurcation diagram. Finally it is demonstrated that chaos sets in. Thus the system belongs to the few three-dimensional autonomous ones modelling physical situations which lead to chaotic behavior.


2018 ◽  
Vol 28 (12) ◽  
pp. 1850151 ◽  
Author(s):  
Valery A. Gaiko ◽  
Cornelis Vuik

We complete the global bifurcation analysis of the Leslie–Gower system with the Allee effect which models the dynamics of the populations of predators and their prey in a given ecological or biomedical system. In particular, studying global bifurcations of limit cycles, we prove that such a system can have at most two limit cycles surrounding one singular point.


2005 ◽  
Vol 40 (3) ◽  
pp. 205-225 ◽  
Author(s):  
Diego M. Alonso ◽  
Eduardo E. Paolini ◽  
Jorge L. Moiola

2015 ◽  
Vol 25 (12) ◽  
pp. 1550170 ◽  
Author(s):  
Li Fan ◽  
Sanyi Tang

In the present paper, we perform a complete bifurcation analysis of a two-stage population model, in which the per capita birth rate and stage transition rate from juveniles to adults are density dependent and take the general Beverton–Holt functions. Our study reveals a rich bifurcation structure including codimension-one bifurcations such as saddle-node, Hopf, homoclinic bifurcations, and codimension-two bifurcations such as Bogdanov–Takens (BT), Bautin bifurcations, etc. Moreover, by employing the polynomial analysis and approximation techniques, the existences of equilibria, Hopf and BT bifurcations as well as the formulas for calculating their bifurcation sets have been provided. Finally, the complete bifurcation diagrams and associate phase portraits are obtained not only analytically but also confirmed and extended numerically.


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