scholarly journals Some techniques for the electrical brain stimulation of small unrestrained animals

1966 ◽  
Vol 4 (4) ◽  
pp. 393-397 ◽  
Keyword(s):  
Brain Stimulation ◽  
Electrical Brain Stimulation ◽  
Stimulation Of

Clinical responses to electrical brain stimulation of the temporal and frontal lobes in patients with epilepsy

Brain ◽  
1993 ◽  
Vol 116 (2) ◽  
pp. 397-414 ◽  
Author(s):  
D. R. Fish ◽  
P. Gloor ◽  
F. L. Quesney ◽  
A. Oliver
Keyword(s):  
Brain Stimulation ◽  
Frontal Lobes ◽  
Electrical Brain Stimulation ◽  
Clinical Responses ◽  
Patients With Epilepsy ◽  
Stimulation Of

scholarly journals Modulation of emotion perception and memory via sub-threshold amygdala stimulation in humans

2019 ◽  
Author(s):  
Krzysztof A. Bujarski ◽  
Yinchen Song ◽  
Sophia I. Kolankiewicz ◽  
Gabriella H. Wozniak ◽  
Angeline S. Andrews ◽  
...  
Keyword(s):  
Brain Stimulation ◽  
Memory Task ◽  
Emotional Valence ◽  
Emotional Memory ◽  
Cognitive Change ◽  
Electrical Brain Stimulation ◽  
Emotional Perception ◽  
Average Valence ◽  
Significant Difference ◽  
Stimulation Of

AbstractA common human experience is noticing that emotional life events are more vividly remembered than dull ones. Studies show that the amygdala plays a central role in such emotionally driven enhancement of memory. With this in mind, we investigated the effect of electrical brain stimulation of the left human amygdala on performance on an emotional perception and emotional memory task. We randomly applied sub-threshold 50 Hz stimulation to the left amygdala in 10 patients (5 female and 5 male) with intracranial electrodes during the encoding portion of an emotional valence perception and emotional memory task. We found that amygdala stimulation did not affect reported valence for neutral stimuli (non-stimulated group average valence 5.34, stimulated 5.38, p=0.68) but it did affect positively (non-stimulated group average valence 7.31, stimulated 6.70, p=0.004) and negatively (non-stimulated group average valence 2.79, stimulated 3.55, p=0.0002) valenced stimuli in effect reporting both valence categories as more neutral. Furthermore, we found that stimulation did not significantly disrupt memory for neutral stimuli (68% vs. 61% correctly remembered p=0.48) or positive stimuli (87% vs. 70% correct, trend towards significant difference p=0.09) but did for negative stimuli (83% vs. 67% correct, p=0.03). These results suggest that electrical brain stimulation by our parameters likely reversibly inhibits amygdala function disrupting neural networks responsible for emotional perception and memory. This effect may have clinical implications in treatment of certain neuropsychiatric disorders, such as emotional dysregulation and post-traumatic stress disorder.Statement of significanceThe current study builds and expands on extensive prior research into the function of the human amygdala. It provides the first systematic description in humans of a cognitive change brought about by direct electrical stimulation of the amygdala on perception of emotional valence and emotional memory. The results provide further evidence on the importance of the amygdala in human cognition. Likewise, out method utilized to study the function of the amygdala can be extended to study the function of other brain regions in humans, such as the cingulate. While these results are preliminary and need to be duplicated, we aim to further study the effects of amygdala stimulation on emotional processing including possible therapeutic application for diverse group of neuropsychiatric conditions.

Electrical brain stimulation of the parietal lobe impairs the perception of verticality

2019 ◽  
Vol 266 (S1) ◽  
pp. 146-148 ◽  
Author(s):  
O. Kremmyda ◽  
V. Kirsch ◽  
S. Bardins ◽  
H. Lohr ◽  
C. Vollmar ◽  
...  
Keyword(s):  
Brain Stimulation ◽  
Parietal Lobe ◽  
Electrical Brain Stimulation ◽  
Perception Of Verticality ◽  
Stimulation Of

scholarly journals An MRI Compatible Brain Probe for Signal Recording and Deep Brain Stimulation

2018 ◽  
Author(s):  
Corey Cruttenden ◽  
Mahdi Ahmadi ◽  
Xiao-Hong Zhu ◽  
Wei Chen ◽  
Rajesh Rajamani
Keyword(s):  
Electrical Stimulation ◽  
Brain Stimulation ◽  
Neurological Diseases ◽  
Neural Tissue ◽  
Electrical Brain Stimulation ◽  
Thalamic Nuclei ◽  
Disease Therapy ◽  
Signal Recording ◽  
Deep Brain ◽  
Stimulation Of

Electrical stimulation of neural tissue is a promising therapy for a variety of neurological diseases. For example, electrical stimulation of deep thalamic nuclei has been used extensively to treat symptoms of Parkinson’s disease, and there is growing interest in treating other conditions including epilepsy and depression with similar techniques. However, the mechanisms of electrical brain stimulation for disease therapy are not fully understood [1].

Differences in Extinction in Electrical Brain-Stimulation under Traditional Procedures of Reward Presentation

1965 ◽  
Vol 16 (3) ◽  
pp. 909-913 ◽  
Author(s):  
Roger W. McIntire ◽  
James E. Wright
Keyword(s):  
Electrical Stimulation ◽  
Brain Stimulation ◽  
Water Reinforcement ◽  
Electrical Brain Stimulation ◽  
Resistance To Extinction ◽  
Dry Water ◽  
The Brain ◽  
Stimulation Of ◽  
The Way

Rats were trained to bar-press for electrical stimulation of the brain (ESB) or H2O reinforcement in order to examine differences in resistance to extinction as related to method of presentation of reward. The methods of presentation of ESB were: (1) immediate with the appropriate bar-press, (2) immediate with the appropriate bar-press with addition of a momentarily presented dry water cup, (3) immediate with the licking of the water cup presented on appropriate bar-press. Also, a group working for one lick of water and no ESB was included. The data show clearly that H2O reinforcement is superior in producing higher resistance to extinction and that presentation of ESB reinforcement in a manner similar to the way in which a water reinforcement is presented gives higher resistance to extinction than presenting ESB reinforcement contingent only on the bar-press.

Psychomodulation by bilateral deep brain stimulation of the lateral habenula in a patient with long-lasting, therapy-refractory major depression

2009 ◽  
Vol 42 (05) ◽  
Author(s):  
A Sartorius ◽  
K Kiening ◽  
C von Gall ◽  
U Haberkorn ◽  
AW Unterberg ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Major Depression ◽  
Brain Stimulation ◽  
Lateral Habenula ◽  
Deep Brain ◽  
Stimulation Of

Fear and Depression as Side Effect of Deep Brain Stimulation of the Subthalmic Nucleus in Parkinson's Disease

2004 ◽  
Vol 35 (03) ◽  
Author(s):  
M Sabolek ◽  
I Uttner ◽  
K Seitz ◽  
A Storch
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Side Effect ◽  
Deep Brain ◽  
Stimulation Of
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