Supplementation with evening primrose oil in atopic dermatitis: Effect on fatty acids in neutrophils and epidermis

Lipids ◽  
1991 ◽  
Vol 26 (7) ◽  
pp. 557-560 ◽  
Author(s):  
Liselotte Schäfer ◽  
Knud Kragballe
Keyword(s):  
Fatty Acids ◽  
Atopic Dermatitis ◽  
Evening Primrose Oil ◽  
Evening Primrose

scholarly journals Essential fatty acids in the liver and adipose tissue of genetically obese mice: effect of supplemental linoleic and γ-linolenic acids

1985 ◽  
Vol 53 (3) ◽  
pp. 441-448 ◽  
Author(s):  
S. C Cunnane ◽  
M. S. Manku ◽  
D. F. Horrobin
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Essential Fatty Acids ◽  
Coconut Oil ◽  
Obese Mice ◽  
Evening Primrose Oil ◽  
Oenothera Biennis ◽  
Evening Primrose ◽  
Total Fatty Acids ◽  
Tissue Lipids

1. Genetically obese mice (ob/ob) and their lean litter-mates were given diets iso-energetically supplemented with sucrose, hydrogenated coconut oil, safflower oil or evening primrose (Oenothera biennis) oil.2. Weight gain over 15 weeks was significantly greater in the evening primrose oil-supplemented obese mice than in the other groups.3. In all the groups of obese mice, liver total phospholipids contained proportionally less linoleic acid and more dihomo-γ-linolenic acid and arachidonic acid than did the lean controls.4. As a percentage of total fatty acids, n-3 essential fatty acids (EFA) in liver and adipose tissue lipids were significantly lower in the obese mice than in the lean controls.5. Supplementation with EFA-rich oils (safflower and evening primrose oil) increased the proportional composition of n-6 EFA and decreased the n-3 EFA more in the liver total phospholipids of the lean than the obese mice.

scholarly journals Synergistic Effects of Korean Red Ginseng Extract and the Conventional Systemic Therapeutics of Atopic Dermatitis in a Murine Model

Nutrients ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 133
Author(s):  
Yu Ri Woo ◽  
Seok Hoon Moon ◽  
Jeesuk Yu ◽  
Sang Hyun Cho
Keyword(s):  
Atopic Dermatitis ◽  
Synergistic Effects ◽  
Transepidermal Water Loss ◽  
Evening Primrose Oil ◽  
Red Ginseng ◽  
Korean Red Ginseng ◽  
Ginseng Extract ◽  
Evening Primrose ◽  
Group A ◽  
Ad Mouse Model

The synergistic effects of Korean Red ginseng (KRG, Panax ginseng C.A. Mey.) on conventional systemic therapeutics of atopic dermatitis (AD) have not been studied yet. To analyze the synergistic effects of KRG extract and the conventional systemic therapeutics of AD in TNCB-induced AD mouse model, we determined the change in modified scoring of index, the transepidermal water loss, the skin pathology, serum IgE, and the expression of various cytokines after combination treatment to the five-week-old NC/Nga female mice. The severity of AD was significantly decreased in the KRG + hydroxyzine (AH) group than AH group, and in the KRG + evening primrose oil (EPO) group than EPO group. A significant decrease in dermal inflammation was observed in the KRG + AH group than that in the AH group, and in the KRG + EPO group than that in the EPO group (p = 0.008), respectively. A decrease in CD1a expression was observed in the KRG + AH group when compared to the AH group (p = 0.008), and KRG + EPO group when compared to the EPO group. Compared to the CS group, the KRG + CS group showed a significant decrease in IL-17 expression. A combination of KRG and conventional systemic therapeutics can safely and effectively manage the AD.

Sign in / Sign up

Export Citation Format

Share Document