Evening Primrose Oil Has Mixed Effects on Serum Fatty Acids

InPharma ◽  
1989 ◽  
Vol 673 (1) ◽  
pp. 16-16
Keyword(s):  
Fatty Acids ◽  
Mixed Effects ◽  
Evening Primrose Oil ◽  
Evening Primrose ◽  
Serum Fatty Acids

scholarly journals Essential fatty acids in the liver and adipose tissue of genetically obese mice: effect of supplemental linoleic and γ-linolenic acids

1985 ◽  
Vol 53 (3) ◽  
pp. 441-448 ◽  
Author(s):  
S. C Cunnane ◽  
M. S. Manku ◽  
D. F. Horrobin
Keyword(s):  
Fatty Acids ◽  
Adipose Tissue ◽  
Essential Fatty Acids ◽  
Coconut Oil ◽  
Obese Mice ◽  
Evening Primrose Oil ◽  
Oenothera Biennis ◽  
Evening Primrose ◽  
Total Fatty Acids ◽  
Tissue Lipids

1. Genetically obese mice (ob/ob) and their lean litter-mates were given diets iso-energetically supplemented with sucrose, hydrogenated coconut oil, safflower oil or evening primrose (Oenothera biennis) oil.2. Weight gain over 15 weeks was significantly greater in the evening primrose oil-supplemented obese mice than in the other groups.3. In all the groups of obese mice, liver total phospholipids contained proportionally less linoleic acid and more dihomo-γ-linolenic acid and arachidonic acid than did the lean controls.4. As a percentage of total fatty acids, n-3 essential fatty acids (EFA) in liver and adipose tissue lipids were significantly lower in the obese mice than in the lean controls.5. Supplementation with EFA-rich oils (safflower and evening primrose oil) increased the proportional composition of n-6 EFA and decreased the n-3 EFA more in the liver total phospholipids of the lean than the obese mice.

Dietary essential fatty acid supplementation, urinary calcium excretion and reproductive performance in the diabetic pregnant rat

1997 ◽  
Vol 153 (3) ◽  
pp. 357-363 ◽  
Author(s):  
H O Garland ◽  
A G Forshaw ◽  
C P Sibley
Keyword(s):  
Fatty Acids ◽  
Reproductive Performance ◽  
Sunflower Oil ◽  
Essential Fatty Acids ◽  
Diabetic Rats ◽  
Urinary Calcium ◽  
Standard Diet ◽  
Evening Primrose Oil ◽  
Pregnant Rats ◽  
Evening Primrose

Abstract Hypercalciuria may be a contributory factor to the disturbed calcium homoeostasis seen in diabetic pregnant rats and their offspring. In diabetes, essential fatty acid metabolism is impaired. We have therefore investigated whether feeding a diet supplemented with essential fatty acids will ameliorate the hypercalciuria of diabetic pregnancy and improve reproductive performance. Female rats were fed a standard rat diet, a fat-free diet plus evening primrose oil or a fat-free diet plus sunflower oil. They were injected with streptozotocin or vehicle and mated. Urine samples were analysed for calcium before injection and during gestation. Term-pregnant diabetic rats fed evening primrose oil showed a 73% reduction in urinary calcium output compared with similar rats fed standard diet (P<0·001). The corresponding reduction was 44% in diabetic rats fed sunflower oil (P<0·001). A depletion of essential fatty acids in diabetes may therefore be associated with hypercalciuria; dietary supplementation, particularly with evening primrose oil, appears to correct the problem. Diabetic pregnant rats fed evening primrose oil showed a significantly greater live fetal mass (85 ± 2 vs 33 ± 12 g; P<0·05) compared with similar rats fed standard diet. Such findings may imply a normalization of placental transport by essential fatty acids. Rats fed evening primrose, but not sunflower oil, also showed a reduced incidence of diabetes after streptozotocin injection compared with rats fed standard diet (63 vs 86%). Rats fed on evening primrose oil that did become diabetic were less hyperglycaemic than those on the standard diet (29 ± 2 vs 37 ± 2 mmol/l), suggesting that the oil may have anti-diabetic properties. Journal of Endocrinology (1997) 153, 357–363

scholarly journals Effect of microbial oil, evening primrose oil and borage oil on rumen fermentation in vitro

2012 ◽  
Vol 50 (No. 11) ◽  
pp. 480-486 ◽  
Author(s):  
D. Jalc ◽  
A. Potkanski ◽  
M. Szumacher-Strabel ◽  
A. Cieslak ◽  
M. Certik
Keyword(s):  
Fatty Acids ◽  
Fatty Acid Content ◽  
Rumen Fermentation ◽  
Borage Oil ◽  
Microbial Oil ◽  
Evening Primrose Oil ◽  
Evening Primrose ◽  
Fermentation Vessel ◽  
Chain Fatty Acids

The objective of this study was to examine the effects of microbial oil, evening primrose oil and borage oil on rumen fermentation of a diet consisting of 80% of hay and 20% of barley in an artificial rumen (Rusitec). All three oils contained gamma-linolenic acid (GLA), microbial oil &ndash; 8.4%, evening primrose oil &ndash; 9.2% and borage oil &ndash; 23.7% out of the total fatty acid content. The experiment in Rusitec lasted 11 days. After a stabilization period (5 days), microbial oil (5% wt/wt) was added into fermentation vessel V<sub>2</sub>, evening primrose oil (5% wt/wt) into V<sub>3</sub> and borage oil (5%wt/wt) into V<sub>4</sub> (6 days). Fermentation vessel V<sub>1</sub> served as a control (without oils). The results showed that the oils did not affect any of the basal parameters of rumen fermentation (pH, NH<sub>3</sub>-N, degradation of dry matter, organic matter, neutral detergent fibre, acid detergent fibre). Methane production (mmol/day) was reduced numerically by the oils; microbial oil, evening primrose oil and borage oil decreased CH<sub>4</sub> production about 11.32%, 11.45% and 2.04%, respectively. The supplementation of the oils to the total mixed ration (TMR) significantly decreased percentage proportions of short-chain fatty acids (SCFA, about 0.1&ndash;0.3%), medium-chain fatty acids (MCFA, about 8%) and increased long-chain fatty acids (LCFA, about 8%) in the effluent. Stearic acid C<sub>18:0</sub> was the major FA in the effluent and was significantly reduced in oil supplemented diets. The percentage proportion of trans C<sub>18:1</sub> isomers significantly increased (1.7&ndash;2 times) in all oil supplemented diets. The main intermediates &ndash; cis 9, trans 11 C<sub>18:2</sub> (CLA) and trans 11 C<sub>18:1 </sub>(TVA) also increased after oil supplementation of the diet. TVA concentration with microbial oil, evening primrose oil and borage oil supplementation was 3.17%, 8.19% and 9.3% in comparison with the control (1.38%). CLA concentration significantly increased 2.3, 1.2, and 2.1 times after microbial oil, evening primrose oil and borage oil supplementation in Rusitec. Finally, the oil supplementation caused incomplete biohydrogenation of unsaturated FA and it was characterized by an increase in TVA concentration and TVA to C<sub>18:0</sub> ratio in oil supplemented diets.

Sign in / Sign up

Export Citation Format

Share Document