The medical management of peptic ulcer (II) practical aspect of gastric ulcer at ariga clinic

Background and objectives: Aegle marmelos (Bael), a medicinal plant, has been widely used indigenously to treat many diseases in Bangladesh and other countries. The present study was carried out to evaluate the efficacy of A. marmelos leaf to prevent ethanol induced gastric ulcer in a rat model.Methods: Thirty two Wister albino rats of either sex, weighing between 100-150g, were fed 200 mg/kg or 400 mg/kg aqueous extract of A. marmelos leaves one hour prior to oral administration of 90% ethanol (1 ml/200 gm body weight) to induce gastric ulcer. The animals were sacrificed after one hour and ulcer scores and index were determined. The protective efficacy of A. marmelos aqueous extract was expressed as percentage protection of ulcer.Results: Aqueous extract exhibited significant (p<0.05) dose dependent protection against gastric ulcer formation by ethanol in rat stomach. Percentage protection of ulcer with 200 mg/kg and 400 mg/kg of aqueous extract of A. marmelos leave were 19.3% and 37.2% respectively compared to standard anti-peptic ulcer drug omeprazole (50.4%).Conclusion: Thus, crude extracts of A. marmelos leave have been shown to have potential ability to prevent experimentally induced peptic ulcer formation in animal model.IMC J Med Sci 2018; 12(1): 11-14

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Evaluation of a poly-herbal preparation for the treatment of peptic ulcer

Bangladesh Journal of Pharmacology ◽

10.3329/bjp.v12i2.29980 ◽

2017 ◽

Vol 12 (2) ◽

pp. 11

Author(s):

Zaman Hayat ◽

Mueen Ahmad Chaudhry ◽

. Alamgeer

Keyword(s):

Peptic Ulcer ◽

Gastric Ulcer ◽

Treated Group ◽

Ulcer Formation ◽

Ulcer Index ◽

Herbal Formulation ◽

High K ◽

Ulcer Model ◽

Dose Dependent ◽

Gross Examination

<p class="Abstract">The aim of this study was to validate the traditional uses of ulcerene, a poly-herbal formulation in ethanol, aspirin and stress-induced gastric ulcer model of rat. The extent of gastric ulcer formation was studied, using ulcer score, ulcer index, percentage cure through gross examination and histopathological evaluation. A significant (p<0.001) dose-dependent anti-ulcerant effect was observed in ulcerene (50 and 100 mg/kg)-treated group with highest effectiveness against ethanol-induced ulcer. The concentration-dependent spasmolytic effect was seen in spontaneously contracting, high K<sup>+</sup> (80 mM) and carbachol (1 µM)-induced jejunum contractions (10, 0.3 and 1 mg/mL), similar to dicyclomine (10, 1 and 3 µM), indicated non-specific spasmolytic mechanism behind the effect. By considering these results, ulcerene can be suggested for the treatment of peptic ulcer.</p>

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GASTRIC ULCER OF THE PYLORUS SIMULATING. HYPERTROPHIC PYLORIC STENOSIS

PEDIATRICS ◽

10.1542/peds.6.6.897 ◽

1950 ◽

Vol 6 (6) ◽

pp. 897-907

Author(s):

ARTHUR R. C. COLE

Keyword(s):

Differential Diagnosis ◽

Peptic Ulcer ◽

Gastric Ulcer ◽

Pyloric Stenosis ◽

Recent Literature ◽

Hypertrophic Pyloric Stenosis ◽

Diagnostic Procedures ◽

Peptic Ulcers ◽

Infancy And Childhood ◽

History Of

A brief review of the natural history of peptic ulcer in infancy and childhood is given. The symptomatology, differential diagnosis and diagnostic procedures are presented. The diagnosis of peptic ulcer should be considered more often in infancy and childhood and the proper diagnostic procedures instituted. A case of gastric ulcer simulating hypertrophic pyloric stenosis is presented. A summary of 31 cases with peptic ulcers found at autopsy at the Babies Hospital from January 1, 1924 to January 1, 1950 is given. From a summary of coexistent disease found in the autopsy cases at the Babies Hospital and reports from the recent literature, it would appear that diseases of the central nervous, gastrointestinal and respiratory systems are commonly present in cases which have shown peptic ulcer at autopsy.

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Features of the course of peptic ulcer disease in children and adolescents

Kazan medical journal ◽

10.17816/kazmj62135 ◽

1985 ◽

Vol 66 (5) ◽

pp. 377-377

Author(s):

N. A. Cherkasova ◽

H. S. Bikbulatova ◽

V. N. Leonova

Keyword(s):

Duodenal Ulcer ◽

Peptic Ulcer ◽

Gastric Ulcer ◽

Peptic Ulcer Disease ◽

Children And Adolescents ◽

Ulcer Disease

There were 26 patients with gastric ulcer and duodenal ulcer (17 boys, 9 girls) aged from 9 to 18 years under observation.

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Acute pancreatitis

Oxford Textbook of Medicine ◽

10.1093/med/9780199204854.003.152401_update_001 ◽

2010 ◽

pp. 2557-2567

Author(s):

R. Carter ◽

C.J. McKay

Keyword(s):

Acute Pancreatitis ◽

Peptic Ulcer ◽

Gastric Ulcer ◽

Abdominal Pain ◽

Serum Amylase ◽

Perforated Peptic Ulcer ◽

Upper Limit ◽

Abdominal Emergencies ◽

Idiopathic Acute Pancreatitis ◽

Upper Abdominal

Acute pancreatitis affects 300 to 600 new patients per million population per year and is most commonly caused by gallstones or alcohol, but there are many other causes and associations. Careful imaging reveals that most so-called idiopathic acute pancreatitis is due to small (1–3 mm diameter) gallstones. Diagnosis is made by a combination of a typical presentation (upper abdominal pain and vomiting) in conjunction with raised serum amylase (> × 3 upper limit of normal) and/or lipase (> × 2 upper limit of normal). Several acute abdominal emergencies can mimic acute pancreatitis and may be associated with a raised serum amylase. These include perforated peptic ulcer (particularly perforated posterior gastric ulcer) and acute mesenteric ischaemia. In equivocal cases, a CT scan is indicated in order to exclude other causes and confirm the diagnosis....

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