Protective effects for hepatocytes ofSalviae miltiorrhiza andPaeonia lactiflora in experimental liver damage

1995 ◽  
Vol 1 (3) ◽  
pp. 227-230
Author(s):  
Xin-guang Qi ◽  
Inagaki Yutaka
Keyword(s):  
Liver Damage ◽  
Protective Effects ◽  
Experimental Liver ◽  
Experimental Liver Damage

Protective and Therapeutic Effects of Ban-zhi-lian on Hepatotoxin-induced Liver Injuries

1994 ◽  
Vol 22 (01) ◽  
pp. 29-42 ◽  
Author(s):  
Song-chow Lin ◽  
Chun-ching Lin ◽  
Yun-ho Lin ◽  
Ching-hsein Chen
Keyword(s):  
Liver Damage ◽  
Experimental Models ◽  
Therapeutic Effects ◽  
Protective Effects ◽  
Liver Injuries ◽  
Serum Glutamate Pyruvate Transaminase ◽  
Glutamate Pyruvate ◽  
Experimental Liver ◽  
Serum Glutamate ◽  
Experimental Liver Damage

The hepatoprotective effect of Ban-zhi-lian was investigated in three kinds of experimental models. The animals were treated with Ban-zhi-lian (300 mg/kg, p.o.) at 2, 4, and 10 hours after carbon tetrachloride (32l/kg, i.p.), acetaminophen (600 mg/kg, i.p.), and β-D-galactosamine (188 mg/kg, i.p.) administration. Significant protective effects from these hepatotoxins were expressed. This protection was evidenced by comparing the serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), and histopathologic examination in animals treated and untreated with Ban-zhi-lian. Serum enzyme activities were significantly lower in Ban-zhi-lian-treated groups. In the histopathologic observation, liver damage induced by three hepatotoxins was markedly improved in Ban-zhi-lian treated animals. These results demonstrated that Ban-zhi-lian has a protective effect against experimental liver damage induced by various hepatotoxins.

Yang-Gan-Wan Protects Mice Against Experimental Liver Damage

2000 ◽  
Vol 28 (02) ◽  
pp. 155-162 ◽  
Author(s):  
Melissa Yang ◽  
Kevin Chen ◽  
Jean Chen Shih
Keyword(s):  
Carbon Tetrachloride ◽  
Liver Damage ◽  
Alanine Aminotransferase ◽  
Allyl Alcohol ◽  
Herbal Remedy ◽  
Hepatoprotective Effect ◽  
Protective Effects ◽  
Chinese Herbal ◽  
Experimental Liver ◽  
Experimental Liver Damage

The hepatoprotective effect of Yang-Gan-Wan (YGW, Pro-Liver pill), a Chinese herbal remedy, was investigated in mice that were treated with allyl alcohol (AlOH), acetaminophen (AA) or carbon tetrachloride ( CCl 4). Mice were pretreated daily with 200 mg/kg YGW for 10, 14 and 18 days before treatment with 85 mg/kg AlOH, 475 mg/kg AA or 20 μl/kg CCl 4, respectively. YGW dramatically abolished the elevated activities of alanine aminotransferase (ALT) and sorbitol dehydrogenase (SDH) and reduced the nectosis induced by AlOH. YGW also decreased the elevated activities of ALT and SDH and reduced the necrosis induced by AA and CCl 4. This study demonstrates that YGW has protective effects against liver damage induced by AlOH, AA, and CCl 4.

scholarly journals Influence of the Escherichia coli Nissle 1917 strain on complications of the chronic experimental liver damage

2008 ◽  
Vol 52 (No. 3) ◽  
pp. 121-129
Author(s):  
D. Kosakova ◽  
P. Scheer ◽  
J. Lata ◽  
J. Doubek
Keyword(s):  
Escherichia Coli ◽  
Lymph Nodes ◽  
Liver Damage ◽  
Weight Ratio ◽  
Coliform Bacteria ◽  
Control Group ◽  
Significant Difference ◽  
And Control ◽  
Experimental Liver ◽  
Experimental Liver Damage

The aim of the study was evaluate the influence of the probiotic <i>Escherichia coli</i> Nissle 1917 strain (Mutaflor&reg; suspension, Ardeypharm GmbH, Herdecke, Germany) on bacterial translocation in cases of liver damage, damage to the intestinal mucosa, potential portal hypertension associated with possible development of oesophageal varices and on the bacterial population of the intestine during chronic experimental liver damage in the laboratory rat. Rats with liver damage induced by thioacetamide were divided into an experimental and control group. Experimental and control animals were applied Mutaflor and saline, respectively. Samples of blood, liver, lymph nodes and caecum for microbiological examination, of liver, duodenum and oesophagus for histological examination and of spleen for weight evaluation were collected. There were no significant differences between both groups of animals in the qualitative proportion of <i>Staphylococcus</i> spp., <i>Enterococcus</i> spp. and <i>Proteus</i> spp. cultured from the lymph nodes, blood and liver. The quantitative culture results on <i>Enterococcus</i> spp. in the caecum, liver and lymph nodes showed no significant differences between both groups. There was a significant difference between the experimental and control group in the counts of coliform bacteria. No significant differences between both groups were found in the overall damage score of the liver, duodenum and oesophagus. There were no differences in the spleen to body weight ratio of both groups. The application of Mutaflor&reg; suspension for eight days had no recognisable effect diminishing the selected complications of chronic liver damage caused by the administration of TAA to laboratory rats.

Hepatoprotective effect of ethanolic extract ofEclipta alba on experimental liver damage in rats and mice

1993 ◽  
Vol 7 (2) ◽  
pp. 154-158 ◽  
Author(s):  
B. Singh ◽  
A. K. Saxena ◽  
B. K. Chandan ◽  
S. G. Agarwal ◽  
M. S. Bhatia ◽  
...  
Keyword(s):  
Liver Damage ◽  
Ethanolic Extract ◽  
Hepatoprotective Effect ◽  
Rats And Mice ◽  
Experimental Liver ◽  
Experimental Liver Damage

Changes in activation of aspartate aminotransferase by pyridoxal 5'-phosphate after experimental liver damage in rabbits

1982 ◽  
Vol 122 (3) ◽  
pp. 395-401 ◽  
Author(s):  
A. de Waal ◽  
S. le Roux ◽  
G.M. Potgieter ◽  
H.C. Barnard ◽  
E.M.S.P. Schoombie
Keyword(s):  
Liver Damage ◽  
Aspartate Aminotransferase ◽  
Experimental Liver ◽  
Experimental Liver Damage

Behavior of Serum Glycoprotein and Haptoglobin Levels in Experimental Liver Damage in Rats

Pharmacology ◽  
1966 ◽  
Vol 14 (5) ◽  
pp. 485-492
Author(s):  
I. Piukovich ◽  
L. Varga ◽  
M. Gábor ◽  
M. Tényi ◽  
E. Horváth ◽  
...  
Keyword(s):  
Liver Damage ◽  
Serum Glycoprotein ◽  
Experimental Liver ◽  
Experimental Liver Damage
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