Establishment of a cell line infected with SRS mouse leukemia virus and its biological characteristics

1992 ◽  
Vol 4 (2) ◽  
pp. 24-28 ◽  
Author(s):  
Li Cheng ◽  
Xianshou Kong ◽  
Baofen Zheng
Keyword(s):  
Cell Line ◽  
Leukemia Virus ◽  
Biological Characteristics ◽  
Mouse Leukemia ◽  
Mouse Leukemia Virus ◽  
A Cell

Aberrant Type C Virus Production in a Cell Line Derived from Balb/3T3

1972 ◽  
Vol 30 ◽  
pp. 286-287
Author(s):  
N. Savage ◽  
A. Hackett
Keyword(s):  
Electron Microscopy ◽  
Cell Line ◽  
Leukemia Virus ◽  
Morphological Characteristics ◽  
Virus Production ◽  
Oncogenic Viruses ◽  
Endogenous Virus ◽  
Virus Particles ◽  
Moloney Leukemia Virus ◽  
A Cell

A cell line, UC1-B, which was derived from Balb/3T3 cells, maintains the same morphological characteristics of the non-transformed parental culture, and shows no evidence of spontaneous virus production. Survey by electron microscopy shows that the cell line consists of spindle-shaped cells with no unusual features and no endogenous virus particles.UC1-B cells respond to Moloney leukemia virus (MLV) infection by a change in morphology and growth pattern which is typical of cells transformed by sarcoma virus. Electron microscopy shows that the cells are now variable in shape (rounded, rhomboid, and spindle), and each cell type has some microvilli. Virtually all (90%) of the cells show virus particles developing at the cell surface and within the cytoplasm. Maturing viruses, typical of the oncogenic viruses, are found along with atypical tubular forms in the same cell.

Biological and Pathogenic Properties of a Mouse Leukemia Virus

1960 ◽  
Vol 23 (5) ◽  
pp. 259-275 ◽  
Author(s):  
Ludwik Gross
Keyword(s):  
Leukemia Virus ◽  
Mouse Leukemia ◽  
Mouse Leukemia Virus

Eine Komplementbindungsreaktion zum Nachweis der bei Leukämieviren verschiedener Säuger vorkommenden gemeinsamen antigenen Komponente

1970 ◽  
Vol 25 (9) ◽  
pp. 1029-1036 ◽  
Author(s):  
Werner Schäfer ◽  
Jens Lange ◽  
Liselotte Pister ◽  
Eveline Seifert ◽  
Fernando de Noronha ◽  
...  
Keyword(s):  
Tissue Culture ◽  
Cancer Cells ◽  
Human Cancer ◽  
Leukemia Virus ◽  
Mouse Leukemia ◽  
Human Cancer Cells ◽  
Mouse Leukemia Virus ◽  
Bovine Leukosis

By immunization of a rabbit with purified gs-antigen from mouse leukemia virus (MLV) a potent antiserum (R-gs-serum) was obtained, which reacts specifically with gs-antigen of MLV.In cat leukemia virus (KLV) two types of antigens, probably both group specific, could be demonstrated with anti-KLV-sera by Ouchterlony test. One of these was shown with MLV-sera to be identical with a MLV-gs-antigen component. This antigen occurring in both viruses is called gsinterspecies (interspec.) antigen.R-gs-serum allowed to detect gs-interspec. antigen also by the more sensitive CF-test. [Lispa (leukemia virus interspec. antigen) CF-test]. Preliminary experiments with this test indicated that bovine leukosis as well as human cancer cells can produce an agent in tissue culture which is serologically related to MLV.

RNA-Dependent Synthesis of DNA by Virions of Mouse Leukemia Virus

1970 ◽  
Vol 35 (0) ◽  
pp. 843-846 ◽  
Author(s):  
D. Baltimore
Keyword(s):  
Leukemia Virus ◽  
Mouse Leukemia ◽  
Mouse Leukemia Virus

scholarly journals Establishment and some biological characteristics of a cell line derived from Yamame embryonal liver.

1988 ◽  
Vol 54 (11) ◽  
pp. 1881-1887 ◽  
Author(s):  
Tadaaki Moritomo ◽  
Hiroyoshi Asakawa ◽  
Masanori Nakano ◽  
Tasuku Watanabe
Keyword(s):  
Cell Line ◽  
Biological Characteristics ◽  
A Cell

scholarly journals Primer Binding Site-Dependent Restriction of Murine Leukemia Virus Requires HP1 Binding by TRIM28

2008 ◽  
Vol 82 (9) ◽  
pp. 4675-4679 ◽  
Author(s):  
Daniel Wolf ◽  
Florence Cammas ◽  
Régine Losson ◽  
Stephen P. Goff
Keyword(s):  
Binding Site ◽  
Cell Line ◽  
Murine Leukemia Virus ◽  
Leukemia Virus ◽  
Embryonic Stem ◽  
Transcriptional Silencing ◽  
Primer Binding Site ◽  
A Cell ◽  
Ec Cells ◽  
Murine Leukemia

ABSTRACT TRIM28 is a transcriptional corepressor which is required for primer binding site (PBS)-dependent restriction of murine leukemia virus (MLV) replication in embryonic stem and embryonic carcinoma (EC) cells. PBS-dependent restriction of MLV leads to transcriptional silencing of the integrated provirus and has been shown to correlate with TRIM28-mediated recruitment of HP1 to the silenced loci. Here we show, using a cell line with a point mutation in the HP1 binding domain of TRIM28, that interaction with HP1 is absolutely required for the PBS-dependent restriction of MLV in the F9 EC cell line.

scholarly journals Nucleic acid and proteins isolated from the Rauscher mouse leukemia virus (MLV).

1966 ◽  
Vol 55 (1) ◽  
pp. 219-227 ◽  
Author(s):  
P. H. Duesberg ◽  
W. S. Robinson
Keyword(s):  
Nucleic Acid ◽  
Leukemia Virus ◽  
Mouse Leukemia ◽  
Mouse Leukemia Virus

Malignant transformation in a tissue culture infected with a mouse leukemia virus

1968 ◽  
Vol 23 (1-2) ◽  
pp. 169-174 ◽  
Author(s):  
J. G. Sinkovics ◽  
F. Gy�rkey ◽  
Glenda F. Groves ◽  
Phyllis Gy�rkey
Keyword(s):  
Tissue Culture ◽  
Malignant Transformation ◽  
Leukemia Virus ◽  
Mouse Leukemia ◽  
Mouse Leukemia Virus
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