1.8 A Functional LDL Receptor-Related Protein 6 Gene Variant is an Independent Risk Factor For Early Carotid Artery Atherosclerosis in Hypertensive Patients

2008 ◽  
Vol 15 (3) ◽  
pp. 178-178
Author(s):  
R. Sarzani ◽  
F. Salvi ◽  
M. Bordicchia ◽  
F. Guerra ◽  
I. Battistoni ◽  
...  
Keyword(s):  
Risk Factor ◽  
Carotid Artery ◽  
Independent Risk Factor ◽  
Ldl Receptor ◽  
Gene Variant ◽  
Related Protein ◽  
Hypertensive Patients ◽  
Carotid Artery Atherosclerosis

scholarly journals Subclinical Carotid Artery Atherosclerosis and Cognitive Function: A Mini-Review

2021 ◽  
Vol 12 ◽  
Author(s):  
Håkon Ihle-Hansen ◽  
Hege Ihle-Hansen ◽  
Else Charlotte Sandset ◽  
Guri Hagberg
Keyword(s):  
Risk Factor ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Carotid Artery ◽  
Independent Risk Factor ◽  
Carotid Atherosclerosis ◽  
Vascular Risk ◽  
Risk Factor Management ◽  
Carotid Artery Atherosclerosis ◽  
Non Invasive

Carotid artery atherosclerosis, the result of a multitude of vascular risk factors, is a promising marker for use in risk stratification. Recent evidence suggests that carotid artery atherosclerosis affects cognitive function and is an independent risk factor for the development of cognitive impairment. Both atherosclerosis and cognitive impairment develop over a prolonged period (years), and due to the aging population, markers to identify persons at risk are needed. Carotid artery atherosclerosis can easily be visualized using non-invasive ultrasound, potentially enabling early and intensified risk factor management to preserve cognitive function or delay further decline. However, the burden of atherosclerosis and temporal exposure required to pose a risk of cognitive impairment is unclear. This mini-review aims to explore the available evidence on the association between carotid atherosclerosis and cognition, and furthermore identify the remaining gaps in knowledge.

scholarly journals Serum uric acid is an independent risk factor for cardiovascular disease and mortality in hypertensive patients

2012 ◽  
Vol 35 (11) ◽  
pp. 1087-1092 ◽  
Author(s):  
Tatsuo Kawai ◽  
Mitsuru Ohishi ◽  
Yasushi Takeya ◽  
Miyuki Onishi ◽  
Norihisa Ito ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Uric Acid ◽  
Risk Factor ◽  
Serum Uric Acid ◽  
Independent Risk Factor ◽  
Hypertensive Patients

What Have We Learned from the Imaging in Carotid Angioplasty and Risk of Stroke (ICAROS) Study?

Vascular ◽  
2004 ◽  
Vol 12 (1) ◽  
pp. 62-68 ◽  
Author(s):  
Giorgio M. Biasi ◽  
Alberto Froio ◽  
Gaetano Deleo ◽  
Claudia Piazzoni ◽  
Valter Camesasca
Keyword(s):  
Risk Factor ◽  
Clinical Practice ◽  
Carotid Artery ◽  
Carotid Artery Stenting ◽  
Carotid Plaque ◽  
Independent Risk Factor ◽  
Carotid Stenting ◽  
Computer Assisted ◽  
Carotid Angioplasty ◽  
Cerebral Embolization

Carotid artery stenting (CAS) is used widely to treat carotid lesions. Indication to CAS is mostly based, both in trial and in clinical practice, on the percentage of stenosis and the presence or absence of preprocedural neurologic symptoms, whereas the features of the plaque are somehow disregarded and ignored. The most severe complication of CAS is stroke, related to cerebral embolization from carotid plaque. Several studies showed that echolucent plaques generate a higher number of embolic particles following carotid stenting. Echolucency can be measured using the gray scale median, which is an objective and quantitative computer-assisted grading of the echogenicity of carotid plaques. As previously demonstrated in the ICAROS study, carotid plaque echolucency is an independent risk factor for stroke in carotid stenting. Carotid plaque echolucency is one of the parameters that should be mandatory to be considered for indication to treatment.

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