HYPERTENSION — AN AREA OF INTENSE ACTIVITY?

InPharma ◽  
1977 ◽  
Vol 116 (1) ◽  
pp. 19-20
Keyword(s):  
Synthesis ◽  
2021 ◽  
Author(s):  
Yang Xiong ◽  
Sijia Li ◽  
Haijing Xiao ◽  
Guozhu Zhang

In recent years, visible-light-mediated copper photocatalysis have emerged as an attractive strategy for the diverse constructions of basic bonds in an ecologically benign and cost-effective fashion. The intense activity and increasing work of these areas stimulated the exploit of the distinctive properties of copper photocatalysis and the rapid development and expansion of their applications. In this review, we focus on introducing a series of significant achievements in copper complexes as standalone photocatalysis in organic reactions to make an attempt to exhibit their potential capabilities and high flexibilities in synthetic chemistry.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jie Ding ◽  
Anli Tong ◽  
YuShi Zhang ◽  
Hui Zhang ◽  
Li Huo
Keyword(s):  
Pet Ct ◽  

Author(s):  
Glenn McAndrews

Electric starter development programs have been the subject of ASME technical papers for over two decades. Offering significant advantages over hydraulic or pneumatic starters, electric starters are now poised to be the preferred choice amongst gas turbine customers. That they are not now the dominant starter in the field after decades of investment and experimentation is attributable to many factors. As with any new technology, progress is often unsteady, depending on budgets, market conditions, customer buy-in, etc. Additionally, technological advances in the parent technologies, in this case electric motors, can abruptly and rapidly change, further disturbing the best laid introduction plans. It is therefore not too surprising that only recently, is the industry beginning to see the deployment of electric starters on production gas turbines. The earliest adoption occurred on smaller gas turbine units, generally less than 10 MW in power. More recently, gas turbines greater than 10 MWs are being sold with electric starters. The authors expect that regardless of their size or fuel supply, most all future gas turbine users will opt for electric starters. This may even include the “larger” frame machines with power greater than 100 MW. Starting with some past history, this paper will not only summarize past development efforts, it will attempt to examine the current deployment of electric starters throughout the marine and industrial gas turbine landscapes. The large-scale acceptance of electric start systems for both new production and retrofit will depend on the favorable cost/benefit assessment when weighing both first cost and life cycle cost. The current and intense activity in electric vehicle applications is giving rise to even more power dense motors. The paper will look at some of these exciting applications, the installed products, and the technologies behind the products. To what extent these new products may serve the needs of the gas turbine community will be the central question this paper attempts to answer.


eLife ◽  
2015 ◽  
Vol 4 ◽  
Author(s):  
Katharine R Grabek ◽  
Cecilia Diniz Behn ◽  
Gregory S Barsh ◽  
Jay R Hesselberth ◽  
Sandra L Martin

During hibernation, animals cycle between torpor and arousal. These cycles involve dramatic but poorly understood mechanisms of dynamic physiological regulation at the level of gene expression. Each cycle, Brown Adipose Tissue (BAT) drives periodic arousal from torpor by generating essential heat. We applied digital transcriptome analysis to precisely timed samples to identify molecular pathways that underlie the intense activity cycles of hibernator BAT. A cohort of transcripts increased during torpor, paradoxical because transcription effectively ceases at these low temperatures. We show that this increase occurs not by elevated transcription but rather by enhanced stabilization associated with maintenance and/or extension of long poly(A) tails. Mathematical modeling further supports a temperature-sensitive mechanism to protect a subset of transcripts from ongoing bulk degradation instead of increased transcription. This subset was enriched in a C-rich motif and genes required for BAT activation, suggesting a model and mechanism to prioritize translation of key proteins for thermogenesis.


1996 ◽  
Vol 39 (2) ◽  
Author(s):  
R. Carniel ◽  
F. Iacop

In this work we investigate the characteristics of the seismicity at Stromboli volcano during more than two years, i.e. from 11 May 1992 to 21 August 1994. The three paroxysmal phases of 1993 mark significant changes in the Strombolian activity; nevertheless, these are not the only ones observed. In fact, the energy content, both in terms of volcanic tremor and of number of events drops to very low values after the periods of intense activity, accompanied by a change in the spectral content of the tremor. However, equally abrupt changes in the frequency content, not accompanied by evident intensity variations, can be observed some weeks after the end of the crises. The volcano seems therefore to behave like a dynamical system with many «quite stable » states with abrupt transitions between them. An interesting observation is the appearance of an energy concentration in the spectral sectors below 3 Hz before more violent eruptive episodes; although the duration of such a phenomenon is variable, it has to be investigated as a possible precursor of potentially dangerous activity of the volcano. A continuous monitoring of the spectral content of volcanic tremor on Stromboli is confirmed to be an essential tool in order to understand the behaviour of Stromboli volcano and to try to forecast its paroxysmal phases.


1989 ◽  
Vol 40 (2) ◽  
pp. 293-302 ◽  
Author(s):  
Peter M. Neumann

Evidence front published sources is used to show that Cauchy's group-theoretical work was all produced in a few months of intense activity starting in September 1845.


1996 ◽  
Vol 7 (2) ◽  
pp. 121-122 ◽  
Author(s):  
Bruno H. Repp

In a recent article in this journal, Weisberg (1994) examined the hypothesis that creative individuals suffering from manic-depressive disease not only are more productive during hypomanic phases (which they commonly are) but also produce works of higher quality than during normal or depressed periods As his test case, he took the composer Robert Schumann (1810-1856), who suffered from a bipolar affective disorder (Jamison, 1993, Ostwald, 1985, Slater & Meyer, 1959) and who left extensive records of his mood swings in letters and diaries A plot of the number of Schumann's compositions by year of completion (Weisberg's Fig 1) reveals two periods of particularly intense activity the years 1840 and 1849-1851, especially 1849 According to Slater and Meyer (1959), the years 1840, 1849, and 1851 coincide with hypomanic periods in Schumann's life Years classified as mostly depressive periods, by contrast, show very low productivity


Sir George Beilby’s life comprised many activities. He was first and foremost a chemical manufacturer and chemical engineer. During the first twenty years of his professional life (1870-90) his work centred on the manu­facture of ammonia and oils from the Scottish shales. At the end of this period the introduction of the McArthur-Forrest process for the extraction of gold from its ores by potassium cyanide caused him to transfer his attention mainly to the production of this substance. He invented a process for the manufacture of cyanide from ammonia, which for sixteen years (1890-1906) was worked by the Cassel Gold Extracting Company (now the Cassel Cyanide Company), Glasgow. In 1900, in conjunction with Castner, he invented another process of cyanide manufacture, which involved the use of sodium. In consequence of this he joined in that year the Board of the Castner-Kellner Alkali Company, at Runcorn, who manufactured pure caustic soda. This was the raw material for the manufacture of sodium metal by the electrolysis of the fused caustic. The plant for this he erected at Newcastle-on-Tyne, and for the remainder of his life he was actively concerned with the operations of the wroks at Runcorn, Newcastle and Glasgow. For more than half a century, therefore, he occupied a foremost place in the manufacture of nitrogen derivatives. His experience as a manufacturer led him to study the economic utilisation of fuel, and in his presidential address to the Society of Chemical Industry in 1899 he surveyed the various channels of consumption into which the output at that date was flowing. This was the starting point of an inquiry and study which led him to become ultimately the foremost authority on the scientific utilisation of fuel in this country. In 1903 he gave evidence before the Royal Commission on Coal on the output of this mineral and its uses, and made suggestions as to its more economical use. Later he worked for a considerable time on the production of a smokeless fuel for domestic purposes. In 1912-13 he was made a member of the Royal Commission on Fuel and Engines for the Navy. The culmination of his work in this field was his appointment as the first Chairman and Director of the Fuel Research Board in the Department of Scientific and Industrial Research in 1917, a post which gave him the oppor­tunity of putting into practice the conclusions he had formed as to the best methods of utilising scientifically the fuel resources of the country. The war years (1914-18) constituted for him a period of intense activity, and as a member of Lord Fisher’s Central Committee of the Board of Invention and Research, and of the Trench and Chemical Warfare Committees of the War Office and the Ministry of Munitions, he rendered services of the utmost value to the country.


2018 ◽  
Vol 30 (3) ◽  
pp. 472-487 ◽  
Author(s):  
Juan J. Díaz Benítez

The secret supply of the German Navy during the Second World War has scarcely been studied until now. The goal of this article is to study one of the more active supply areas of the Etappendienst at the beginning of the war, the one known as Etappe Kanaren, as part of the Grossetappe Spanien-Portugal. In this research primary sources from German Naval War Command have been consulted. Among the main conclusions, it should be pointed out, on the one hand, the intense activity to support the Kriegsmarine during the first years of the war, despite the distance from mainland Spain and the British pressure, which finally stopped the supply operations. On the other hand, we have confirmed the active role of the Spanish government in relation to the Etappendienst: Spanish authorities allowed the supply operations, but pressure from the Allies forced the Spanish government to impede these activities.


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