Erythrocyte fatty acid composition and insulin sensitivity in daughters of Type 2 diabetic patients and women with no family history of diabetes

Objective: To evaluate the relationship of Serum Leptin and Early Nephropathy among uncontrolled type 2 Diabetes Mellitus patients of Bangladesh Institute of Research and Rehabilitation in Diabetes Endocrinology and Metabolism (BIRDEM), Dhaka and Endocrinology department of Sylhet MAG Osmani Medical College (SOMC) & Hospital Sylhet, Bangladesh. Methods: This study was carried out from January 2013 to December 2015 among 100 type 2 diabetic patients from the outpatient department (OPD) BIRDEM and SOMC hospital. Results: 16 out of 30 controls and 65 out of 100 people with diabetes have a family history of diabetes. Early retinopathy and neuropathy were observed in 45.5% and 36.5% diabetic subjects. Mean±SD of serum urea in control subjects was 28.65±6.27; in diabetic subjects was 30.21±7.67. Serum creatinine in controls was 1.12±0.24, in diabetic subjects was 1.13±0.25. Serum leptin levels in control subjects {1.65 (0.05-8.66)} was lower than diabetic counterpart {1.21 (0.11-13.3)}. Leptin levels in male controls {(1.29 (0.05-2.49)} was significantly (P 0.000) lower than the female controls {4.03 (0.05-8.66)}. Conclusion: It was evident that there was very little or no association between serum leptin level and the indices of renal function. No changes of circulating serum Leptin concentration in the earlier stages of Diabetic Nephropathy were found.

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Serum phospholipid fatty acid composition and insulin action in type 2 diabetic patients

Metabolism ◽

10.1053/meta.2001.27195 ◽

2001 ◽

Vol 50 (12) ◽

pp. 1472-1478 ◽

Cited By ~ 53

Author(s):

Terezie Pelik[aacute]nov[aacute] ◽

Ludmila Kazdov[aacute] ◽

[Scaron][aacute]rka Chvojkov[aacute] ◽

Ji[rcaron][iacute] Ba[scaron]e

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Insulin Action ◽

Phospholipid Fatty Acid ◽

Diabetic Patients ◽

Phospholipid Fatty Acid Composition ◽

Serum Phospholipid ◽

Type 2 Diabetic Patients ◽

Type 2 Diabetic

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Effects of supplementation with omega-3 on insulin sensitivity and non-esterified free fatty acid (NEFA) in type 2 diabetic patients

Arquivos Brasileiros de Endocrinologia & Metabologia ◽

10.1590/0004-2730000002861 ◽

2014 ◽

Vol 58 (4) ◽

pp. 335-340 ◽

Cited By ~ 19

Author(s):

Payam Farahbakhsh Farsi ◽

Abolghassem Djazayery ◽

Mohammad Reza Eshraghian ◽

Fariba Koohdani ◽

Ali Akbar Saboor-Yaraghi ◽

...

Keyword(s):

Placebo Group ◽

Fatty Acid ◽

Insulin Sensitivity ◽

Intervention Group ◽

Diabetic Patients ◽

Omega 3 ◽

Type 2 Diabetic Patients ◽

Study Results ◽

Type 2 Diabetic

Objective: The aim of this study was to determine the role of omega-3 supplementation on NEFA concentration, insulin sensitivity and resistance, and glucose and lipid metabolism in type 2 diabetic patients. Subjects and methods: Forty-four type 2 diabetic patients were randomly recruited into two groups. Group A received 4 g/day omega-3 soft gels, and group B received a placebo for 10 wks. Blood samples were collected after 12-h fast. Physical activity records, three-day food records, and anthropometric measurements were obtained from all participants at the beginning and end of the study. Results: Omega-3 supplementation caused a significant reduction in NEFA in the intervention group compared with the placebo group (P = 0.009). Additionally, the administration of omega-3 resulted in significantly greater changes (Diff) for the intervention group in various parameters, such as insulin and Quicki indices compared with the placebo group (P < 0.05). Conclusions: Omega-3 fatty acid supplementation in type 2 diabetic patients improved insulin sensitivity, probably due to the decrease in NEFA concentrations. Arq Bras Endocrinol Metab. 2014;58(4):335-40

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Effects of cilostazol on serum lipid concentrations and plasma fatty acid composition in type 2 diabetic patients with peripheral vascular disease

Clinical and Experimental Medicine ◽

10.1007/s102380300004 ◽

2003 ◽

Vol 2 (4) ◽

pp. 180-184 ◽

Cited By ~ 19

Author(s):

N. Nakamura ◽

T. Hamazaki ◽

H. Johkaji ◽

S. Minami ◽

K. Yamazaki ◽

...

Keyword(s):

Fatty Acid Composition ◽

Fatty Acid ◽

Serum Lipid ◽

Diabetic Patients ◽

Plasma Fatty Acid ◽

Peripheral Vascular ◽

Type 2 Diabetic Patients ◽

Plasma Fatty Acid Composition ◽

Type 2 Diabetic

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Objectivization of vacuum-compression therapy effects on micro- and macrovascular perfusion in type 2 diabetic patients

Biomedical Engineering / Biomedizinische Technik ◽

10.1515/bmt-2019-0066 ◽

2020 ◽

Vol 65 (4) ◽

pp. 469-476

Author(s):

Jaroslav Prucha ◽

Vladimir Socha ◽

Lenka Hanakova ◽

Andrej Lalis ◽

Karel Hana

Keyword(s):

Lower Limb ◽

Compression Therapy ◽

Neurological Complications ◽

Diabetic Patients ◽

Type 2 Diabetic Patients ◽

Therapeutic Procedures ◽

History Of ◽

Injury Recovery ◽

Type 2 Diabetic

AbstractThe present study aimed to evaluate the characteristic influence of physical therapeutic procedures of vacuum-compression therapy (VCT) on microvascular perfusion (MiP) and macrovascular perfusion (MaP) of the lower limb in diabetic patients. A sample of nine patients with a medical history of type 2 diabetes was used for the purpose of this study. Most of the subjects’ medical conditions included venous and neurological complications of the lower limb, whereas the rest of the subjects entered the treatment due to injury recovery or their phlebological disease. The PeriFlux System 5000 (Perimed, Sweden) diagnostic device was used to measure MiP. The MaP was evaluated based on the perfusion index (PI) using the Extremiter monitoring device (Embitron, Czech Republic) designed to perform VCT procedures. The study found that MiP and MaP increase as an effect of VCT procedures and at the same time PI clearly reflects the effect of the applied vacuum and compression phases, verifying the method’s vital influence on peripheral perfusion disorders.

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