Murphy’s law of particle sizing: comparison of the size distributions of lecithin liposomes obtained by dynamic light scattering and electron microscopy

2008 ◽  
pp. 224-225 ◽  
Author(s):  
S. Egelhaaf ◽  
P. Schurtenberger ◽  
E. Wehrli ◽  
M. Adrian ◽  
P. L. Luisi
Keyword(s):  
Electron Microscopy ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Particle Sizing ◽  
Size Distributions

Synthesis and properties of multiheaded and multitailed surfactants based on tripentaerythritol

2015 ◽  
Vol 93 (5) ◽  
pp. 502-508 ◽  
Author(s):  
Nawal K. Paul ◽  
Tyler Mercer ◽  
Hussein Al-Mughaid ◽  
D. Gerrard Marangoni ◽  
Michael J. McAlduff ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Aqueous Solution ◽  
Surface Tension ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Self Assembly ◽  
Alkyl Chain ◽  
Alkyl Chain Length ◽  
Aggregation Behaviour ◽  
Aggregate Structures

The surface and self-assembly properties of a family of multiheaded, multitailed surfactants based on a tripentaerythritol backbone are described. Critical aggregation concentrations of these unusual surfactant systems have been determined from surface tension measurements; aggregate sizes in the presence and absence of a small amount of added electrolyte have been obtained via dynamic light scattering, and the morphologies of the aggregates were examined from electron microscopy measurements. In general, when compared to conventional ionic and two-headed surfactants (and other recently synthesized pentaerythritol derived surfactants from this group), these multiheaded surfactants exhibited some unusual trends in their aggregation behaviour and interesting aggregate structures in aqueous solution, as a function of alkyl chain length.

Polyethyleneimine Modified Biocompatible Poly(N-isopropylacrylamide)-Based Nanogels for Drug Delivery

2008 ◽  
Vol 8 (5) ◽  
pp. 2377-2384 ◽  
Author(s):  
Chang-Yun Quan ◽  
Hua Wei ◽  
Yun-Xia Sun ◽  
Si-Xue Cheng ◽  
Kun Shen ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Drug Delivery ◽  
Transmission Electron Microscopy ◽  
Light Scattering ◽  
Dynamic Light Scattering ◽  
Transmission Electron ◽  
Potential Applications ◽  
Different Temperatures ◽  
The Mean ◽  
Stimuli Sensitive

A series of biocompatible and stimuli-sensitive poly(N-isopropylacrylamide-co-propyl acrylic acid) (P(NIPAAm-co-PAAc)) nanogels were synthesized by emulsion polymerization. In addition, polyethyleneimine (PEI) was further grafted to modify the PNIPAAm-based nanogels. The P(NIPAAm-co-PAAc)-g-PEI nanogels exhibited good thermosensitivity as well as pH sensitivity. Transmission electron microscopy (TEM) showed that the P(NIPAAm-co-PAAc)-g-PEI and P(NIPAAm-co-PAAc) nanogels displayed well dispersed spherical morphology. The mean sizes of the nanogels measured by dynamic light scattering (DLS) were from 100 nm to 500 nm at different temperatures. The cytotoxicity study indicated P(NIPAAm-co-PAAc) nanogels exhibited a better biocompatibility than both PNIPAAm nanogel and P(NIPAAm-co-PAAc)-g-PEI nanogel although all the three kinds of nanogels did not exhibit apparent cytotoxicity. The drug-loaded nanogels, especially the PEI-grafted nanogels, showed temperature-trigged controlled release behaviors, indicating the potential applications as an intelligent drug delivery system.

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