Single nucleotide polymorphisms in inflammatory genes and the risk of early onset of lone atrial fibrillation

2010 ◽  
Vol 59 (11) ◽  
pp. 965-969 ◽  
Author(s):  
Kristoffer M. A. Henningsen ◽  
Morten S. Olesen ◽  
Maria Pedersen ◽  
Lone Nielsen ◽  
Stig Haunsø ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Single Nucleotide Polymorphisms ◽  
Early Onset ◽  
Nucleotide Polymorphisms ◽  
Lone Atrial Fibrillation ◽  
Single Nucleotide ◽  
Inflammatory Genes

scholarly journals The Effects of Single Nucleotide Polymorphisms in Korean Patients with Early-onset Atrial Fibrillation after Catheter Ablation

2020 ◽  
Vol 35 (49) ◽  
Author(s):  
Yae Min Park ◽  
Seung Young Roh ◽  
Dae In Lee ◽  
Jaemin Shim ◽  
Jong-Il Choi ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Single Nucleotide Polymorphisms ◽  
Early Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Korean Patients ◽  
Onset Atrial Fibrillation

The association of single nucleotide polymorphisms of the maternal cystathionine-β-synthase gene with early-onset preeclampsia

2016 ◽  
Vol 6 (1) ◽  
pp. 60-65 ◽  
Author(s):  
Kim M. Holwerda ◽  
M. Susanne Weedon-Fekjær ◽  
Anne C. Staff ◽  
Ilja M. Nolte ◽  
Harry van Goor ◽  
...  
Keyword(s):  
Single Nucleotide Polymorphisms ◽  
Early Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Early Onset Preeclampsia

scholarly journals Single-Nucleotide Polymorphisms of Vascular Endothelial Growth Factor in Psoriasis of Early Onset

2004 ◽  
Vol 122 (1) ◽  
pp. 209-215 ◽  
Author(s):  
Helen S. Young ◽  
Monica Bhushan ◽  
Christopher E.M. Griffiths ◽  
Angela M. Summers ◽  
Paul E.C. Brenchley
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Single Nucleotide Polymorphisms ◽  
Early Onset ◽  
Vascular Endothelial ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Endothelial Growth Factor

scholarly journals Association of Single Nucleotide Polymorphisms with the Recurrence of Atrial Fibrillation after Catheter Ablation

2011 ◽  
Vol 27 (Supplement) ◽  
pp. SY10_2
Author(s):  
Yu-Feng Hu ◽  
Hung-I Yeh ◽  
Shih-Ann Chen
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

scholarly journals 3321 European Ancestry as a Risk Factor for Atrial Fibrillation in Puerto Rican Hispanics

2019 ◽  
Vol 3 (s1) ◽  
pp. 10-11
Author(s):  
Ariel Gonzalez-Cordero ◽  
Jorge Duconge-Soler ◽  
Ángel López-Candales
Keyword(s):  
Atrial Fibrillation ◽  
Risk Factor ◽  
Single Nucleotide Polymorphisms ◽  
Puerto Rican ◽  
Population Sample ◽  
European Ancestry ◽  
Genetic Admixture ◽  
Control Group ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide

OBJECTIVES/SPECIFIC AIMS: Consequently, we have decided to evaluate the presence of single nucleotide polymorphism (SNP) previously associated with AF on a European-descent population in an attempt to first identify the most common loci present in the PRH population and then search for specific PRH SNP associated with AF. METHODS/STUDY POPULATION: A secondary analysis of a Puerto Rican population sample (n = 120) from The Pharmacogenetics of Warfarin in Puerto Ricans Study will be performed. We will implement data from the 1000 genome project to establish a control group of healthy PRH population. Will evaluate the presence of 111 known single nucleotide polymorphisms associated with AF in Europeans and determine the frequency in PRH population sample, and validate predictability of such SNPs. Using admixture informatic markers (AIM) analysis will determine the percentage of admixture by Yoruba, Native American and Iberic-European. Statistical analysis will include the use of the Pearson Product-Moment Coefficient correlation analysis and multivariate linear regression. For admixture will use Maximum Likelihood Estimation and Markov Chain Monte Carlo models. RESULTS/ANTICIPATED RESULTS: A higher frequency of AF associated European single nucleotide polymorphisms, and an overall higher percentage of European admixture will be associated with atrial fibrillation in Puerto Rican Hispanic patients. DISCUSSION/SIGNIFICANCE OF IMPACT: Our contributions here are expected to be the elucidation of European ancestry as a risk factor for AF. These contributions will be significant because it can provide a robust scientific basis for larger GWAS studies in the Puerto Rican community and further narrow down the mechanism specific to this population. Research in this subject could lead to early identification of patients with high risk of developing atrial fibrillation and further decrease incidence and disease burden in the PRH population. Puerto Rican Hispanics have an exclusive genetic admixture that makes for an appealing research subject that could deliver unique results.

scholarly journals NOVEL SINGLE-NUCLEOTIDE POLYMORPHISMS PREDICT THE RISK OF RECURRENCE IN PATIENTS WITH ATRIAL FIBRILLATION UNDERGOING CATHETER ABLATION

2015 ◽  
Vol 65 (10) ◽  
pp. A273
Author(s):  
Sanghamitra Mohanty ◽  
Prasant Mohanty ◽  
Chintan Trivedi ◽  
Luigi Di Biase ◽  
Pasquale Santangeli ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Single Nucleotide Polymorphisms ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Risk Of Recurrence

Su1074 – Association Between Single Nucleotide Polymorphisms in Il-1β, Il-6 and Il-10 and Early-Onset Colorectal Cancer in Puerto Rican Hispanics

2019 ◽  
Vol 156 (6) ◽  
pp. S-501-S-502
Author(s):  
Jorge J. Cruz-Cruz ◽  
Maria Gonzalez-Pons ◽  
Noe E. Crespo ◽  
Lorena Gonzalez-Sepulveda ◽  
Lenis N. Rovira Torres ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Single Nucleotide Polymorphisms ◽  
Puerto Rican ◽  
Early Onset ◽  
Nucleotide Polymorphisms ◽  
Single Nucleotide ◽  
Early Onset Colorectal Cancer
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