Vitamin D concentrations from neonatal dried blood spots and the risk of early-onset type 2 diabetes in the Danish D-tect case-cohort study

Diabetologia ◽  
2021 ◽  
Author(s):  
Amélie Keller ◽  
Fanney Thorsteinsdottir ◽  
Maria Stougaard ◽  
Isabel Cardoso ◽  
Peder Frederiksen ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Cohort Study ◽  
Early Onset ◽  
Dried Blood Spots ◽  
Onset Type ◽  
Blood Spots

scholarly journals Association Between Age at Diagnosis of Type 2 Diabetes and Cardiovascular Diseases: A Nationwide, Population-Based, Cohort Study

2021 ◽  
Vol 12 ◽  
Author(s):  
Chunyan Hu ◽  
Lin Lin ◽  
Yujing Zhu ◽  
Yi Zhang ◽  
Shuangyuan Wang ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Cardiovascular Diseases ◽  
Early Onset ◽  
Population Based ◽  
Age At Diagnosis ◽  
Onset Type ◽  
Onset Diabetes ◽  
The Impact

ObjectivesNationwide studies focusing on the impact of early-onset type 2 diabetes and obesity on the development of cardiovascular diseases (CVD) are limited in China. We aimed to investigate the association between age at diagnosis of type 2 diabetes and the risk of CVD, and to further examine the modifying effect of obesity on this association among Chinese adults.MethodsThis study included 23,961 participants with previously diagnosed diabetes from a large nationwide population-based cohort study across mainland China. With an interviewer-assisted questionnaire, we collected detailed information on CVDs. Logistic regression analysis was used to evaluate the risk of CVDs associated with age at diagnosis of diabetes.ResultsCompared with patients with late-onset diabetes (≥60 years), those with earlier-onset diabetes had increased risks for CVD, with adjusted ORs (95% CIs) of 1.72 (1.36-2.17), 1.52 (1.31-1.75) and 1.33 (1.19-1.48) for patients diagnosed aged <40, 40-49 and 50-59 years, respectively. Each 5-year earlier age at diagnosis of type 2 diabetes was significantly associated with 14% increased risk of CVD (OR, 1.14; 95%CI, 1.11-1.18). This association was more prominent for patients with obesity than those with normal body mass index (BMI). Significant interaction was detected between age at diagnosis and BMI categories on CVD risk (P for interaction=0.0457).ConclusionEarly-onset type 2 diabetes was significantly associated with higher risk of CVD, and this association was more prominent among patients with obesity.

834-P: Weight Change and Dementia Risk in Patients with New-Onset Type 2 Diabetes: A Nationwide Cohort Study

Diabetes ◽  
2019 ◽  
Vol 68 (Supplement 1) ◽  
pp. 834-P
Author(s):  
HYUK-SANG KWON ◽  
SOON JIB YOO ◽  
MIN-KYUNG LEE ◽  
GA EUN NAM
Keyword(s):  
Type 2 Diabetes ◽  
Cohort Study ◽  
Weight Change ◽  
Onset Type ◽  
Dementia Risk ◽  
New Onset

scholarly journals Missense mutations in theTGM2 gene encoding transglutaminase 2 are found in patients with early-onset type 2 diabetes

2007 ◽  
Vol 28 (11) ◽  
pp. 1150-1150 ◽  
Author(s):  
O. Porzio ◽  
O. Massa ◽  
V. Cunsolo ◽  
C. Colombo ◽  
M. Malaponti ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Early Onset ◽  
Transglutaminase 2 ◽  
Missense Mutations ◽  
Gene Encoding ◽  
Onset Type

scholarly journals Preliminary analysis of immune activation in early onset type 2 diabetes

2013 ◽  
Vol 72 (1) ◽  
pp. 21190 ◽  
Author(s):  
Julia D. Rempel ◽  
Juliet Packiasamy ◽  
Heather J. Dean ◽  
Jonathon McGavock ◽  
Alyssa Janke ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Immune Activation ◽  
Early Onset ◽  
Preliminary Analysis ◽  
Onset Type

Distinct Predictors and Comorbidities in Early Onset Type 2 Diabetes Mellitus Among Asian Indians

2017 ◽  
Vol 15 (9) ◽  
pp. 458-464 ◽  
Author(s):  
Gadadharan Vijayakumar ◽  
Ganapathy K. Sreehari ◽  
Aswathi Vijayakumar ◽  
Abdul Jaleel
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Early Onset ◽  
Asian Indians ◽  
Onset Type

scholarly journals Vitamin D status and the risk of type 2 diabetes: The Melbourne Collaborative Cohort Study

2019 ◽  
Vol 149 ◽  
pp. 179-187 ◽  
Author(s):  
Alicia K. Heath ◽  
Elizabeth J. Williamson ◽  
Allison M. Hodge ◽  
Peter R. Ebeling ◽  
Darryl W. Eyles ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Vitamin D ◽  
Cohort Study ◽  
Vitamin D Status ◽  
Melbourne Collaborative Cohort Study
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