Age-related differences in volumetric bone mineral density, microarchitecture, and bone strength of distal radius and tibia in Chinese women: a high-resolution pQCT reference database study

2015 ◽  
Vol 26 (6) ◽  
pp. 1691-1703 ◽  
Author(s):  
V. W. Y. Hung ◽  
T. Y. Zhu ◽  
W.-H. Cheung ◽  
T.-N. Fong ◽  
F. W. P. Yu ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
High Resolution ◽  
Bone Strength ◽  
Distal Radius ◽  
Bone Mineral ◽  
Chinese Women ◽  
Reference Database ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density ◽  
Age Related

Ischemic heart disease is associated with lower cortical volumetric bone mineral density of distal radius

2015 ◽  
Vol 26 (7) ◽  
pp. 1893-1901 ◽  
Author(s):  
J. Paccou ◽  
M. H. Edwards ◽  
K. A. Ward ◽  
K. A. Jameson ◽  
C. L. Moss ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Distal Radius ◽  
Bone Mineral ◽  
Ischemic Heart ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

Bone Evaluation by High-Resolution Peripheral Quantitative Computed Tomography in Patients With Adrenal Incidentaloma

2020 ◽  
Vol 105 (8) ◽  
pp. e2726-e2737
Author(s):  
Aline Barbosa Moraes ◽  
Marcela Pessoa de Paula ◽  
Francisco de Paula Paranhos-Neto ◽  
Emanuela Mello Ribeiro Cavalari ◽  
Felipe Fernandes Cordeiro de Morais ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
High Resolution ◽  
Distal Radius ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Adrenal Incidentaloma ◽  
Peripheral Quantitative Computed Tomography ◽  
Mineral Density ◽  
X Ray

Abstract Context Data regarding high-resolution peripheral quantitative computed tomography (HR-pQCT) in patients with adrenal incidentaloma (AI) are unknown. Purpose To evaluate the areal bone mineral density (aBMD), microstructure, and fractures in patients with nonfunctioning AI (NFAI) and autonomous cortisol secretion (ACS). Methods We evaluated 45 patients with NFAI (1 mg dexamethasone suppression test [DST] ≤1.8 µg/dL) and 30 patients with ACS (1 mg DST 1.9-5.0 µg/dL). aBMD was measured using dual-energy X-ray absorptiometry; vertebral fracture by spine X-ray; and bone geometry, volumetric bone mineral density (vBMD), and microstructure by HR-pQCT. Results Patients with ACS showed lower aBMD values at the spine, femoral neck, and radius 33% than those with NFAI. Osteoporosis was frequent in both groups: NFAI (64.9%) and ACS (75%). Parameters at the distal radius by HR-pQCT were decreased in patients with ACS compared to those with NFAI: trabecular vBMD (Tb.vBMD, P = 0.03), inner zone of the trabecular region (Inn.Tb.vBMD, P = 0.01), the bone volume/tissue volume ratio (BV/TV, P = 0.03) and trabecular thickness (P = 0.04). As consequence, a higher ratio of the outer zone of the trabecular region/inner zone vBMD (Meta/Inn.vBMD, P = 0.003) was observed. A correlation between the cortisol levels after 1 mg DST and Meta/Inn.vBMD ratio was found (r = 0.29; P = 0.01). The fracture frequency was 73.7% in patients with ACS vs 55.6% in patients with NFAI (P = 0.24). Conclusion Our findings point to an association between trabecular bone microarchitectural derangement at the distal radius and ACS. Our data suggest that AI have a negative impact on bone when assessed by HR-pQCT, probably associated to subclinical hypercortisolism.

Age-Related Bone Mineral Density, Bone Loss Rate, Prevalence of Osteoporosis, and Reference Database of Women at Multiple Centers in China

2007 ◽  
Vol 10 (3) ◽  
pp. 276-284 ◽  
Author(s):  
Xiao-Guang Cheng ◽  
Ding-Zhuo Yang ◽  
Qi Zhou ◽  
Tie-Jun Zhuo ◽  
Hua-Chou Zhang ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Loss ◽  
Bone Mineral ◽  
Loss Rate ◽  
Reference Database ◽  
Mineral Density ◽  
Age Related ◽  
Bone Loss Rate ◽  
Prevalence Of Osteoporosis

Age-related changes in bone biochemical markers and their relationship with bone mineral density in normal Chinese women

2006 ◽  
Vol 24 (5) ◽  
pp. 380-385 ◽  
Author(s):  
Yin-Zhen Pi ◽  
Xian-Ping Wu ◽  
Shi-Ping Liu ◽  
Xiang-Hang Luo ◽  
Xing-Zhi Cao ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Biochemical Markers ◽  
Chinese Women ◽  
Mineral Density ◽  
Bone Biochemical Markers ◽  
Age Related ◽  
Age Related Changes

scholarly journals A 6-Year Follow-Up of Fracture Incidence and Volumetric Bone Mineral Density Development in Girls With Turner Syndrome

2017 ◽  
Vol 103 (3) ◽  
pp. 1188-1197 ◽  
Author(s):  
Ondrej Soucek ◽  
Eckhard Schönau ◽  
Jan Lebl ◽  
Johannes Willnecker ◽  
Zdenek Hlavka ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Turner Syndrome ◽  
Bone Strength ◽  
Bone Mineral ◽  
Osteoporotic Fractures ◽  
Volumetric Bone Mineral Density ◽  
Fracture Rate ◽  
Mineral Density ◽  
Bone Parameters ◽  
Normal Bone

Abstract Context Patients with Turner syndrome (TS) are at risk for osteoporotic fractures. Objective The aims of this study were to assess the incidence of clinically important fractures in girls with TS and prospectively describe the development of volumetric bone mineral density (BMD). Design Peripheral quantitative computerized tomography (pQCT) of the radius every other year over the 6 years of observation. Setting Government-funded university referral center. Participants Thirty-two girls with TS, aged 6 to 16 years, were included in the analyses. Fracture incidence was compared with the data in the general population. Bone density and strength were compared with data from 185 healthy girls. Outcomes The main clinical outcome was the fracture occurrence. The secondary outcomes were the changes in Z-scores of the bone parameters. Results Three girls with TS sustained four fractures during 6 years of observation. The fracture rate in TS was not substantially higher than the downward-biased fracture-rate estimate from age-matched, healthy controls (P = 0.48). Whereas the trabecular BMD Z-score decreased with age (β estimate −0.21 ± 0.04, P < 0.001), total bone cross-sectional area correspondingly increased (+0.16 ± 0.04, P < 0.001), which led to normal bone strength. A positive history of incident fractures was not significantly associated with any of the pQCT-derived bone parameters. Conclusions Current pediatric TS patients that are treated with growth hormone and estrogens are not at risk for osteoporotic fractures. Low BMD in TS may be counterweighted by enlarged bone radius, which leads to normal bone strength at the appendicular skeleton.

scholarly journals Relationships between bone geometry, volumetric bone mineral density and bone microarchitecture of the distal radius and tibia with alcohol consumption

Bone ◽  
2015 ◽  
Vol 78 ◽  
pp. 122-129 ◽  
Author(s):  
Julien Paccou ◽  
Mark Hiley Edwards ◽  
Kate Ward ◽  
Karen Jameson ◽  
Rebecca Moon ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Alcohol Consumption ◽  
Distal Radius ◽  
Bone Mineral ◽  
Bone Microarchitecture ◽  
Bone Geometry ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

Peripheral Volumetric Bone Mineral Density in Pre- and Postmenopausal Chinese Women in Hong Kong

2000 ◽  
Vol 67 (1) ◽  
pp. 29-36 ◽  
Author(s):  
L. Qin ◽  
S. K. Au ◽  
K. M. Chan ◽  
M. C. Lau ◽  
J. Woo ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Hong Kong ◽  
Bone Mineral ◽  
Chinese Women ◽  
Volumetric Bone Mineral Density ◽  
Mineral Density

Osteonecrosis diagnosed on MR images of the knee: Relationship to reduced bone mineral density determined by high resolution peripheral quantitative CT

2003 ◽  
Vol 44 (5) ◽  
pp. 525-531 ◽  
Author(s):  
M. Zanetti ◽  
J. Romero ◽  
M. A. Dambacher ◽  
J. Hodler
Keyword(s):  
Bone Mineral Density ◽  
High Resolution ◽  
Distal Radius ◽  
Bone Mineral ◽  
Insufficiency Fracture ◽  
Mr Images ◽  
Mineral Density ◽  
Quantitative Ct ◽  
Tibial Condyle ◽  
The Mean

Purpose: To evaluate if osteonecrosis diagnosed on MR images of the knee relates to reduced bone mineral density (BMD) and may be caused by an insufficiency fracture. Material and Methods: Thirty-two consecutive patients (8 men, 24 women; age range 27–82 years, mean 62 years) with MR findings of osteonecrosis of the femoral or tibial condyle were prospectively included. Trabecular and cortical BMD were measured with high resolution peripheral quantitative CT in the non-dominant distal radius and the tibia of the involved extremity. One tibia was not measured due to posttraumatic deformity. Results: The mean trabecular BMD of the radius was 81% of the young-adult average peak BMD (range 19–160%). The mean cortical BMD in the radius was 86% (range 63–108%). The mean trabecular BMD in the tibia was 92% (range 28–160%). The mean cortical BMD in the tibia was 86% (range 49–132%). The values of the trabecular bone of the distal radius (tibia) were normal in 11 (15) patients, osteopenic in 12 (4), and osteoporotic in 9 (12), respectively. The cortical bone values of the distal radius (tibia) were normal in 12 (13) patients, osteopenic in 12 (12), and osteoporotic in 8 (6), respectively. Conclusion: Osteoporosis and osteopenia are commonly found in patients with osteonecrosis of the knee as diagnosed on MR images. This indicates that for some patients an insufficiency mechanism may be responsible for the MR findings. However, in the patients with normal bone density other reasons for osteonecrosis may be present.

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