Pectoralis muscle area is associated with bone mineral density and lung function in lung transplant candidates

Abstract Background Bone mineral density (BMD) has been positively associated with lung function in patients diagnosed with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis. However, the relationship between BMD and lung function is inconsistent in the general population. Methods To investigate the association between BMD and lung function in a Chinese general population, a total of 1024 adults aged 40–70 years old from Qiliying (an industrial polluted exposure area) and Langgongmiao (the reference area with non-industrial pollution) were recruited and underwent BMD and spirometry tests. Results Both BMD and lung function levels were lower in the exposed area compared to the reference area. In addition, BMD and lung function levels were also lower in females compared to males. Both Spearman and partial correlation analyses showed that BMD was positively correlated with FVC and FEV1. After adjusting linear regression analyses for potential confounding factors, every 0.1 g/cm2 drop in BMD was associated with 53.0 mL decrease in FVC and 33.5 mL decrease in FEV1. Conclusions A reduction of BMD is associated with lower lung function in a general population from China.

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PT07.5: Nutritional Assessment, Vitamin D and Bone Mineral Density in Lung Transplant Program Patients

Clinical Nutrition ◽

10.1016/s0261-5614(16)30324-7 ◽

2016 ◽

Vol 35 ◽

pp. S36-S37

Author(s):

V. Aviles ◽

R. Burgos ◽

H. Segurola ◽

G. Cardenas ◽

M. Giribes ◽

...

Keyword(s):

Bone Mineral Density ◽

Vitamin D ◽

Bone Mineral ◽

Lung Transplant ◽

Nutritional Assessment ◽

Mineral Density ◽

Transplant Program

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Low bone mineral density in COPD patients related to worse lung function, low weight and decreased fat-free mass

Osteoporosis International ◽

10.1007/s00198-007-0371-7 ◽

2007 ◽

Vol 18 (9) ◽

pp. 1309-1309

Author(s):

A. Vrieze ◽

M. H. G. de Greef ◽

P. J. Wijkstra ◽

J. B. Wempe

Keyword(s):

Bone Mineral Density ◽

Lung Function ◽

Bone Mineral ◽

Fat Free Mass ◽

Mineral Density ◽

Low Bone Mineral Density ◽

Copd Patients ◽

Low Weight

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Effect of Rhythmic Gymnastics on Volumetric Bone Mineral Density and Bone Geometry in Premenarcheal Female Athletes and Controls

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/jc.2009-2382 ◽

2010 ◽

Vol 95 (6) ◽

pp. 2755-2762 ◽

Cited By ~ 29

Author(s):

S. Tournis ◽

E. Michopoulou ◽

I. G. Fatouros ◽

I. Paspati ◽

M. Michalopoulou ◽

...

Keyword(s):

Bone Mineral Density ◽

Bone Mineral ◽

Quantitative Computed Tomography ◽

Bone Geometry ◽

Bone Age ◽

Peripheral Quantitative Computed Tomography ◽

Volumetric Bone Mineral Density ◽

Mineral Density ◽

Muscle Area ◽

Positive Effects

Abstract Context and Objective: Weight-bearing exercise during growth exerts positive effects on the skeleton. Our objective was to test the hypothesis that long-term elite rhythmic gymnastics exerts positive effects on volumetric bone mineral density and geometry and to determine whether exercise-induced bone adaptation is associated with increased periosteal bone formation or medullary contraction using tibial peripheral quantitative computed tomography and bone turnover markers. Design and Setting: We conducted a cross-sectional study at a tertiary center. Subjects: We studied 26 elite premenarcheal female rhythmic gymnasts (RG) and 23 female controls, aged 9–13 yr. Main Outcome Measures: We measured bone age, volumetric bone mineral density, bone mineral content (BMC), cortical thickness, cortical and trabecular area, and polar stress strength index (SSIp) by peripheral quantitative computed tomography of the left tibia proximal to the distal metaphysis (trabecular) at 14, 38 (cortical), and 66% (muscle mass) from the distal end and bone turnover markers. Results: The two groups were comparable according to height and chronological and bone age. After weight adjustment, cortical BMC, area, and thickness at 38% were significantly higher in RG (P < 0.005–0.001). Periosteal circumference, SSIp, and muscle area were higher in RG (P < 0.01–0.001). Muscle area was significantly associated with cortical BMC, area, and SSIp, whereas years of training showed positive association with cortical BMC, area, and thickness independent of chronological age. Conclusions: RG in premenarcheal girls may induce positive adaptations on the skeleton, especially in cortical bone. Increased duration of exercise is associated with a positive response of bone geometry.

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P240 Lung function and low bone mineral density in cystic fibrosis

10.1136/thorax-2019-btsabstracts2019.383 ◽

2019 ◽

Author(s):

DK Edwards ◽

SB Carr ◽

P Cullinan

Keyword(s):

Bone Mineral Density ◽

Cystic Fibrosis ◽

Lung Function ◽

Bone Mineral ◽

Mineral Density ◽

Low Bone Mineral Density

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Bone mineral density in patients with coronary artery disease and sarcopenia

Modern Rheumatology Journal ◽

10.14412/1996-7012-2020-3-84-90 ◽

2020 ◽

Vol 14 (3) ◽

pp. 84-90

Author(s):

I. I. Grigorieva ◽

T. A. Raskina ◽

M. V. Letaeva ◽

V. I. Ivanov ◽

V. L. Masenko

Keyword(s):

Bone Mineral Density ◽

Muscle Strength ◽

Bone Mineral ◽

Proximal Femur ◽

Mineral Density ◽

Muscle Area ◽

Male Patients ◽

Group 2 ◽

Skeletal Muscle Area ◽

The Relationship

Objective: to assess the relationship between bone mineral density (BMD) and the muscular apparatus in male patients with coronary heart disease (CHD).Patients and methods. The investigation enrolled 79 male patients (median age, 63 [57; 66] years) with an established diagnosis of CHD verified by coronary angiography.Muscle mass was assessed by multispiral computed tomography, by determining the axial muscle tissue area (cm2 ) at the level of LIII. Muscle strength was measured with a wrist dynamometer. Muscle function was examined using the tests of the Short Physical Performance Battery (SPPB). BMD at the neck and proximal femur as a whole and at the lumbar spine was measured by dual energy X-ray absorptiometry.For comparative analysis, the patients were divided into three groups (EWGSOP, 2010). Group 1 included 31 patients without sarcopenia; Group 2 consisted of 21 patients with presarcopenia; and Group 3 comprised 27 patients with sarcopenia.Results and discussion. Osteopenic syndrome was diagnosed in 34 (43%) patients: osteopenia and osteoporosis in 31 (39%) and 3 (4%) patients, respectively. Normal BMD values were observed in 45 (57%) men. The prevalence of osteopenic syndrome was significantly higher in the patients with sarcopenia than in those with presarcopenia (p=0.050) and was comparable to that in men without sarcopenia (p>0.050). BMD at the neck and proximal femur as a whole was significantly lower in the patients with sarcopenia than in those without sarcopenia or with presarcopenia (p<0.050). There was a direct correlation between BMD and the characteristics of muscle mass and muscle strength. Regression analysis showed that the total skeletal muscle area at the level of LIII had a significant direct impact on BMD at the neck and proximal femur as a whole, and the reverse – walking speed.Conclusion. The relationship between the characteristics of the muscular apparatus and BMD requires further investigation.

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