Automated online solid-phase extraction of albendazole and its metabolites in Chinese mitten crabs followed by stable isotope dilution UPLC–MS/MS analysis

We developed an online solid-phase extraction LC–MS/MS method to simultaneously measure 5-methyl-2′-deoxycytidine and 5-hydroxymethyl-2′-deoxycytidine in DNA. We demonstrated that 5-methyl-2′-deoxycytidine is present in Caenorhabditis elegans and its level was regulated by decitabine or cadmium in a dose–response manner.

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Optimization of Clean-up Process Conditions by Comparative Analysis of Dispersive Solid Phase Extraction and Automated Micro Solid Phase Extraction Clean-up for GC-MS/MS Analysis of Pesticides in Tuber Crops

Analytical Chemistry Letters ◽

10.1080/22297928.2021.1877196 ◽

2021 ◽

Vol 11 (1) ◽

pp. 29-38

Author(s):

Sarvendra Pratap Singh ◽

Jyoti Sharma

Keyword(s):

Comparative Analysis ◽

Solid Phase Extraction ◽

Solid Phase ◽

Process Conditions ◽

Phase Extraction ◽

Dispersive Solid Phase Extraction ◽

Ms Analysis ◽

Tuber Crops

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Sensitive determination of gentamicin in plasma using ion-exchange solid-phase extraction followed by UHPLC-MS/MS analysis

Practical Laboratory Medicine ◽

10.1016/j.plabm.2021.e00246 ◽

2021 ◽

pp. e00246

Author(s):

Ana Laura Anibaletto dos Santos ◽

Anne Caroline Cezimbra da Silva ◽

Lilian de Lima Feltraco Lizot ◽

Anelise Schneider ◽

Roberta Zilles Hahn ◽

...

Keyword(s):

Ion Exchange ◽

Solid Phase Extraction ◽

Solid Phase ◽

Phase Extraction ◽

Ms Analysis ◽

Sensitive Determination

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Gas Chromatographic/Mass Spectrometric Confirmation of Leucomalachite Green in Catfish (Ictalurus punctatus) Tissue

Journal of AOAC International ◽

10.1093/jaoac/78.4.971 ◽

1995 ◽

Vol 78 (4) ◽

pp. 971-977 ◽

Cited By ~ 27

Author(s):

Sherri B Turnipseed ◽

José E Roybal ◽

Jeffrey A Hurlbut ◽

Austin R Long

Keyword(s):

Solid Phase Extraction ◽

Ictalurus Punctatus ◽

Solid Phase ◽

Mass Spectrometric ◽

Phase Extraction ◽

Neutral Alumina ◽

Ms Analysis ◽

Solid Phase Extraction Cartridge ◽

Leucomalachite Green ◽

Chromatographic Mass

Abstract A gas chromatographic/mass spectrometric (GC/MS) method was developed to confirm the presence of leucomalachite green (LMG), a metabolite of the triphenylmethane dye malachite green (MG), in catfish tissue. Residues were isolated according to a previously described liquid chromatographic (LC)A/IS spectrometric analysis of MG and LMG in fish. In our isolation procedure, analytes are extracted from tissue with acetonitrile–buffer, partitioned into CH2CI2, and applied to neutral alumina and propylsulfonic acid solid-phase extraction cartridges. Before GC/MS analysis, extracts prepared for the LC determinative method are eluted from a cyano solid-phase extraction cartridge, extracted into organic solvent, and concentrated for GC/MS analysis. Selected ion monitoring was performed by using 5 diagnostic ions (m/z 330,329,253,210, and 165) of LMG. The method was validated by confirming LMG in tissue fortified with mixtures of MG and LMG (5 and 10 ng/g each) and in tissue from fish that had been exposed to low levels of MG.

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