The Role of Tumor Necrosis Factor Alpha and TNF Superfamily Members in Bone Damage in Patients with End-Stage Chronic Obstructive Lung Disease Prior to Lung Transplantation

2016 ◽  
Vol 99 (6) ◽  
pp. 578-587 ◽  
Author(s):  
Evgenia A. Kochetkova ◽  
Vera A. Nevzorova ◽  
Ludmila G. Ugai ◽  
Yulia V. Maistrovskaia ◽  
Gilbert Massard
Keyword(s):  
Obstructive Lung Disease ◽  
Chronic Obstructive Lung Disease ◽  
Chronic Obstructive ◽  
Necrosis Factor Alpha ◽  
Tnf Superfamily ◽  
Bone Damage ◽  
Factor Alpha ◽  
End Stage ◽  
Necrosis Factor

scholarly journals The Role of TNF-αand TNF Superfamily Members in the Pathogenesis of Calcific Aortic Valvular Disease

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Antonella Galeone ◽  
Domenico Paparella ◽  
Silvia Colucci ◽  
Maria Grano ◽  
Giacomina Brunetti
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis ◽  
Experimental Studies ◽  
Calcific Aortic Valve Disease ◽  
Necrosis Factor Alpha ◽  
Major Morbidity ◽  
Tnf Superfamily ◽  
Factor Alpha ◽  
Necrosis Factor

Calcific aortic valve disease (CAVD) represents a slowly progressive pathologic process associated with major morbidity and mortality. The process is characterized by multiple steps: inflammation, fibrosis, and calcification. Numerous studies focalized on its physiopathology highlighting different “actors” for the multiple “acts.” This paper focuses on the role of the tumor necrosis factor superfamily (TNFSF) members in the pathogenesis of CAVD. In particular, we discuss the clinical and experimental studies providing evidence of the involvement of tumor necrosis factor-alpha (TNF-α), receptor activator of nuclear factor-kappa B (NF-κB) ligand (RANKL), its membrane receptor RANK and its decoy receptor osteoprotegerin (OPG), and TNF-related apoptosis-inducing ligand (TRAIL) in valvular calcification.

The role of interleukin-6 and tumor necrosis factor alpha gene in fat and bone communication

2016 ◽  
Author(s):  
Chunyu Wang ◽  
Li Tian ◽  
Kun Zhang ◽  
Yaxi Chen ◽  
Xiang Chen ◽  
...  
Keyword(s):  
Tumor Necrosis Factor ◽  
Tumor Necrosis Factor Alpha ◽  
Interleukin 6 ◽  
Tumor Necrosis ◽  
Necrosis Factor Alpha ◽  
Factor Alpha ◽  
Alpha Gene ◽  
Necrosis Factor
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