The effect of codeine on gastrointestinal transit in extensive and poor metabolisers of debrisoquine

1997 ◽  
Vol 53 (2) ◽  
pp. 145-148 ◽  
Author(s):  
J. Hasselström ◽  
Q. Y. Yue ◽  
J. Säwe
Keyword(s):  
Gastrointestinal Transit ◽  
Poor Metabolisers

Pharmacological blockade and genetical ablation of the Cannabinoid-1 (CB-1) receptor stimulates peristaltic reflex and gastrointestinal transit

2005 ◽  
Vol 43 (10) ◽  
Author(s):  
B Yuece ◽  
A Sibaev ◽  
G Marsicano ◽  
B Lutz ◽  
HD Allescher ◽  
...  
Keyword(s):  
Gastrointestinal Transit ◽  
Peristaltic Reflex ◽  
Pharmacological Blockade

An easy and low-cost biomagnetic methodology to study regional gastrointestinal transit in rats

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Leonardo Pinto ◽  
Guilherme Soares ◽  
André Próspero ◽  
Erick Stoppa ◽  
Gabriel Biasotti ◽  
...  
Keyword(s):  
Low Cost ◽  
Gastrointestinal Transit ◽  
Alternate Current ◽  
Phenol Red ◽  
Distal Small Intestine ◽  
Reliable Assessment ◽  
Imaging Approach ◽  
Magnetic Tracer ◽  
Tracer Distribution ◽  
Gi Transit

Abstract The identification of gastrointestinal (GI) motility disorders requires the evaluation of regional GI transit, and the development of alternative methodologies in animals has a significant impact on translational approaches. Therefore, the purpose of this study was to validate an easy and low-cost methodology (alternate current biosusceptometry – ACB) for the assessment of regional GI transit in rats through images. Rats were fed a test meal containing magnetic tracer and phenol red, and GI segments (stomach, proximal, medial and distal small intestine, and cecum) were collected to assess tracer’s retention at distinct times after ingestion (0, 60, 120, 240, and 360 min). Images were obtained by scanning the segments, and phenol red concentration was determined by the sample’s absorbance. The temporal retention profile, geometric center, gastric emptying, and cecum arrival were evaluated. The correlation coefficient between methods was 0.802, and the temporal retention of each segment was successfully assessed. GI parameters yielded comparable results between methods, and ACB images presented advantages as the possibility to visualize intrasegmental tracer distribution and the automated scan of the segments. The imaging approach provided a reliable assessment of several parameters simultaneously and may serve as an accurate and sensitive approach for regional GI research in rats.

scholarly journals “Masato de Yuca” and “Chicha de Siete Semillas” Two Traditional Vegetable Fermented Beverages from Peru as Source for the Isolation of Potential Probiotic Bacteria

2021 ◽  
Author(s):  
Teresa D. Rebaza-Cardenas ◽  
Kenneth Silva-Cajaleón ◽  
Carlos Sabater ◽  
Susana Delgado ◽  
Nilda D. Montes-Villanueva ◽  
...  
Keyword(s):  
Gastrointestinal Transit ◽  
Probiotic Strain ◽  
In Vitro Digestion ◽  
Intestinal Cell ◽  
Adhesion Ability ◽  
Intestinal Cell Line ◽  
Carbohydrate Fermentation ◽  
Traditional Vegetable ◽  
Genetic Profiles

AbstractIn this work, two Peruvian beverages “Masato de Yuca,” typical of the Amazonian communities made from cassava (Manihot esculenta), and “Chicha de Siete Semillas,” made from different cereal, pseudo-cereal, and legume flours, were explored for the isolation of lactic acid bacteria after obtaining the permission of local authorities following Nagoya protocol. From an initial number of 33 isolates, 16 strains with different RAPD- and REP-PCR genetic profiles were obtained. In Chicha, all strains were Lactiplantibacillus plantarum (formerly Lactobacillus plantarum), whereas in Masato, in addition to this species, Limosilactobacillus fermentum (formerly Lactobacillus fermentum), Pediococcus acidilactici, and Weissella confusa were also identified. Correlation analysis carried out with their carbohydrate fermentation patterns and enzymatic profiles allowed a clustering of the lactobacilli separated from the other genera. Finally, the 16 strains were submitted to a static in vitro digestion (INFOGEST model) that simulated the gastrointestinal transit. Besides, their ability to adhere to the human epithelial intestinal cell line HT29 was also determined. Following both procedures, the best probiotic candidate was Lac. plantarum Ch13, a robust strain able to better face the challenging conditions of the gastrointestinal tract and showing higher adhesion ability to the intestinal epithelium in comparison with the commercial probiotic strain 299v. In order to characterize its benefit for human health, this Ch13 strain will be deeply studied in further works.

scholarly journals Identification and Transferability of Tetracycline Resistance in Streptococcus thermophilus during Milk Fermentation, Storage, and Gastrointestinal Transit

Fermentation ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 65
Author(s):  
Armin Tarrah ◽  
Shadi Pakroo ◽  
Viviana Corich ◽  
Alessio Giacomini
Keyword(s):  
Efflux Pump ◽  
Acquired Resistance ◽  
Gastrointestinal Transit ◽  
Tetracycline Resistance ◽  
Lactobacillus Delbrueckii ◽  
Genomic Islands ◽  
Resistant Bacteria ◽  
Human Pathogens ◽  
Resistance Level ◽  
Milk Fermentation

The existence of antibiotic-resistant bacteria in food products, particularly those carrying acquired resistance genes, has increased concerns about the transmission of these genes from beneficial microbes to human pathogens. In this study, we evaluated the antibiotic resistance-susceptibility patterns of 16 antibiotics in eight S. thermophilus strains, whose genome sequence is available, using phenotypic and genomic approaches. The minimal inhibitory concentration values collected revealed intermediate resistance to aminoglycosides, whereas susceptibility was detected for different classes of β-lactams, quinolones, glycopeptide, macrolides, and sulfonamides in all strains. A high tetracycline resistance level has been detected in strain M17PTZA496, whose genome analysis indicated the presence of the tet(S) gene and the multidrug and toxic compound extrusion (MATE) family efflux pump. Moreover, an in-depth genomic analysis revealed genomic islands and an integrative and mobilizable element (IME) in the proximity of the gene tet(S). However, despite the presence of a prophage, genomic islands, and IME, no horizontal gene transfer was detected to Lactobacillus delbrueckii subsp. lactis DSM 20355 and Lactobacillusrhamnosus GG during 24 h of skim milk fermentation, 2 weeks of refrigerated storage, and 4 h of simulated gastrointestinal transit.

Physicochemical properties and antioxidant activity of gluten-free riceberry-cheese cracker under simulated gastrointestinal transit

2021 ◽  
Author(s):  
Araya Ranok ◽  
Pornchanok Dissamal ◽  
Chanida Kupradit ◽  
Chompoonuch Khongla ◽  
Sumalee Musika ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Physicochemical Properties ◽  
Gastrointestinal Transit ◽  
Gluten Free

Fluoroscopic evaluation of gastrointestinal transit time in African Grey parrots

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
M. Kubiak ◽  
N. A. Forbes
Keyword(s):  
Transit Time ◽  
Gastrointestinal Transit ◽  
Gastrointestinal Transit Time

scholarly journals Effects of Dietary Fiber on Gastrointestinal Transit Time, Fecal Properties and Fat Absorption in Rats.

1995 ◽  
Vol 176 (4) ◽  
pp. 227-238 ◽  
Author(s):  
AKIHIRO MUNAKATA ◽  
SATORU IWANE ◽  
MASAHIRO TODATE ◽  
SHIGEYUKI NAKAJI ◽  
KAZUO SUGAWARA
Keyword(s):  
Dietary Fiber ◽  
Transit Time ◽  
Gastrointestinal Transit ◽  
Fat Absorption ◽  
Gastrointestinal Transit Time
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