Plexiform fibrohistiocytic tumor: imaging features and clinical findings

AbstractAn 11-year-old girl presented with vomiting, nystagmus, and ataxia. MRI showed a partially enhancing medulla oblongata lesion and an adjacent nonenhancing cystic exophytic lesion. An exophytic brainstem tumor was suspected. Histologically, the lesion was identified as a neurenteric cyst (NC). On retrospective review, the NC was connected to the brainstem by a subtle sinus tract. This led to brainstem inflammation which reversed once the cyst was resected. We describe an unreported case of a patient with a NC at the craniocervical junction connected to the brainstem through a sinus tract and discuss the possible embryological abnormality and imaging features.

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Typical and atypical CT chest imaging findings of novel coronavirus 19 (COVID-19) in correlation with clinical data: impact on the need to ICU admission, ventilation and mortality

Egyptian Journal of Radiology and Nuclear Medicine ◽

10.1186/s43055-020-00339-3 ◽

2020 ◽

Vol 51 (1) ◽

Author(s):

Doaa M. Emara ◽

Nagy N. Naguib ◽

M. A. Moustafa ◽

Salma M. Ali ◽

Amr Magdi El Abd

Keyword(s):

Pleural Effusion ◽

Complete Recovery ◽

Clinical Findings ◽

Mediastinal Lymphadenopathy ◽

Imaging Features ◽

Imaging Findings ◽

Icu Admission ◽

Mortality Outcome ◽

Novel Coronavirus ◽

Contrast Ct

Abstract Background The aim of this study was to highlight the typical and atypical chest CT imaging features at first presentation in 120 patients who were proved to be COVID-19 by PCR and to correlate these findings with the need for ICU admission, ventilation, and mortality. We retrospectively included 120 patients 71 males (59.2%) and 49 females (40.8%) with a mean age of 47.2 ± 14.4 years. Patients subjected to clinical assessment, CBC, PCR for COVID-19, and non-contrast CT chest at first presentation. Typical and atypical imaging findings were reported and correlated with the clinical findings of the patients, the need for ICU admission, ventilation, and mortality. Results Clinically, fever was seen in 112 patients followed by dry cough in 108 patients and malaise in 35 patients. The final outcome was complete recovery in 113 cases and death in 7 cases. Typical CT findings included bilateral peripheral ground-glass opacities (GGO) in 74.7%, multilobar affection in 92.5% while atypical findings such as homogeneous consolidation, pleural effusion, mediastinal lymphadenopathy, and single lobar affection were found in 13.4, 5, 6.7, and 7.5% respectively. A statistically significant association between the presence of white lung, pleural effusion, peripheral GGO, and the need for ICU admission as well as mechanical ventilation was noted. The death was significantly higher among elderly patients; however, no significance was found between the imaging features and mortality. Conclusion CT features at first presentation can predict the need for ICU admission and the need for ventilation but cannot predict the mortality outcome of the patients.

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Abdominal Wall Endometriosis: Clinical Presentation And Imaging Features with Emphasis on Sonography

Bangladesh Journal of Obstetrics & Gynaecology ◽

10.3329/bjog.v29i1.30436 ◽

2016 ◽

Vol 29 (1) ◽

pp. 3-8

Author(s):

Quorrata Eynul Forhad ◽

Ali Akbar Biswas ◽

Sk Monirul Islam ◽

Md Shah Alam

Keyword(s):

Cesarean Section ◽

Abdominal Wall ◽

Power Doppler ◽

Clinical Findings ◽

Imaging Features ◽

Palpable Mass ◽

Scar Endometriosis ◽

Abdominal Wall Endometriosis ◽

Cystic Changes ◽

Pathological Material

Objective(s): The purpose of our study was to evaluate clinical findings and sonographic features of abdominal wall endometriosis and also to report its CT and MRI appearance.Materials and methods: A retrospective study was performed from January 2008 - December 2012, yielding 12 surgically proven cases of abdominal wall endometriosis. All patients had undergone sonography including power Doppler examination. Additional CT was performed in one case and MRI in four. Pathological material was preoperatively obtained by sonographically guided puncture in six patients. The clinical data were analyzed and the imaging studies were reviewed by radiologist working in consensus.Results: All patients had a history of at least one prior cesarean section. All patients C/S was done in this institution and 1500 C/S were performed within a period of 5 years giving a frequency of 0.8% scar endometriosis after C/S. All presented with focal pain near the surgical scar, which was cyclic in three patients. Nine patients presented with a palpable mass near the scar. Sonography detected 11 lesions within the abdominal wall with a mean diameter 25mm and in one case sonography could not identify any lesion. All lesions were hypoechoic, vascular, and solid, with some cystic changes in one. MRI CT scan showed enhancement of the lesions. Finally histopathologically all were proved as endometriosis.Conclusion: Abdominal wall endometriosis frequently presents with noncyclic symptoms. Imaging findings of a solid mass near a cesarean section scar strongly suggest its diagnosis.Bangladesh J Obstet Gynaecol, 2014; Vol. 29(1) : 3-8

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Acute bacterial nephritis. A descriptive study of an underdiagnosed entity

Revista Mexicana de Urología ◽

10.48193/rmu.v80i3.556 ◽

2020 ◽

Vol 80 (3) ◽

pp. 1-10

Author(s):

Pedro Antonio Madero-Morales ◽

Rigoberto Pallares-Méndez ◽

Rodrigo Romero-Mata ◽

Guillermo Vizcarra-Mata ◽

Andrés Guillén-Lozoya

Keyword(s):

Acute Pyelonephritis ◽

Clinical Characteristics ◽

Clinical Course ◽

Case Series ◽

Therapy Response ◽

Time Frame ◽

Clinical Findings ◽

Imaging Features ◽

Imaging Studies ◽

Retrospective Case

Background: Acute bacterial nephritis is an infectious process diagnosed through imaging studies. The clinical course of the disease has been shown to be more aggressive than acute pyelonephritis. It continues to be underdiagnosed, thus there are few studies on the entity in the literature. Objective: To describe the clinical characteristics and imaging features of acute bacterial nephritis, as well as its clinical course. Design: A descriptive, retrospective case series was conducted. Materials and methods: Thirty-two cases of acute bacterial nephritis in patients admitted to the hospital within the time frame of 2009 to 2016 were reviewed. The patients’ clinical characteristics upon admission were registered, as well as inpatient clinical progression, culture results, and antibiotic therapy response. The imaging studies were re-evaluated and the diagnostic consistency with either the focal or multifocal disease presentation was confirmed. Results: Cases predominated in women (n=29, 90.62%) and the most frequently associated comorbidities were diabetes (n=16, 50%) and obesity (n=9, 28.25%). The most important clinical findings upon admission were fever (n=15, 46.87%) and leukocytosis (n=27, 84.38%). Escherichia coli was the most commonly isolated bacterium (63.63%). Both acute focal bacterial nephritis and acute multifocal bacterial nephritis were observed in 46.87% (n=15) and 53.13% (n=17) of the patients, respectively. Imaging studies were required for all diagnoses. Conclusion: Fever and leukocytosis are the main findings in acute bacterial nephritis. Imaging studies are necessary for making the diagnosis, given that acute pyelonephritis and acute bacterial nephritis cannot be clinically differentiated.

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Encephalotrigeminal Angiomatosis: A Review with Emphasis on Head and Neck Manifestations

Neurographics ◽

10.3174/ng.2000061 ◽

2021 ◽

Vol 11 (3) ◽

pp. 166-174

Author(s):

B.R. Larsen ◽

M.S. Rosztoczy ◽

D.C. Van Tassel ◽

C.R. Larson ◽

S.A. Avedikian ◽

...

Keyword(s):

Head And Neck ◽

Soft Tissues ◽

Clinical Findings ◽

Imaging Features ◽

Facial Soft Tissue ◽

Vascular Abnormalities ◽

Weber Syndrome ◽

The Face ◽

Sturge Weber Syndrome ◽

Tissue Abnormalities

Encephalotrigeminal angiomatosis, also known as Sturge-Weber syndrome or Sturge-Weber-Dimitri disease, is a sporadic congenital neurocutaneous syndrome characterized by angiomas of the face, eyes, and meninges. The typical clinical findings include seizures, a port-wine facial nevus, hemiparesis, and developmental delay. The classic intracranial imaging features of Sturge-Weber syndrome include cerebral hemispheric atrophy, hypervascularity and/or calcification of the cortex, and ipsilateral choroid plexus enlargement. Extracranial findings primarily include the vascular abnormalities of the ocular and facial soft tissues as well as hypertrophy of the calvarial and maxillofacial osseous structures. Additionally, we report involvement of the extraocular muscles, salivary glands, and lacrimal glands, findings that have not been well described in the literature. While a developmental venous pathology underlying Sturge-Weber syndrome has been proposed resulting in many of the findings, the mechanism behind the facial soft-tissue abnormalities and the clinical sequelae associated with these glandular abnormalities is still uncertain.Learning Objective: To recognize typical clinical and various imaging manifestations of Sturge-Weber syndrome, including head and neck and intracranial imaging findings

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Case report of malignant pulmonary parenchymal glomus tumor: imaging features and review of the literature

Clinical Imaging ◽

10.1016/j.clinimag.2015.09.017 ◽

2016 ◽

Vol 40 (1) ◽

pp. 144-147 ◽

Cited By ~ 4

Author(s):

Jane D. Cunningham ◽

Andrew J. Plodkowski ◽

Dilip D. Giri ◽

Sinchun Hwang

Keyword(s):

Case Report ◽

Glomus Tumor ◽

Tumor Imaging ◽

Imaging Features ◽

Review Of The Literature

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Primary carcinosarcoma of the liver: imaging features and clinical findings in six cases and a review of the literature

Cancer Imaging ◽

10.1186/s40644-018-0141-0 ◽

2018 ◽

Vol 18 (1) ◽

Cited By ~ 6

Author(s):

Jing Li ◽

Pan Liang ◽

Dandan Zhang ◽

Jie Liu ◽

Hongkai Zhang ◽

...

Keyword(s):

Clinical Findings ◽

Liver Imaging ◽

Imaging Features ◽

Review Of The Literature

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Clinical findings and imaging features of 67 nasopharyngeal carcinoma patients with postradiation nasopharyngeal necrosis

Chinese Journal of Cancer ◽

10.5732/cjc.012.10252 ◽

2013 ◽

Vol 32 (10) ◽

pp. 533-538 ◽

Cited By ~ 13

Author(s):

Ming-Yuan Chen ◽

Hai-Qiang Mai ◽

Rui Sun ◽

Xiang Guo ◽

Chong Zhao ◽

...

Keyword(s):

Nasopharyngeal Carcinoma ◽

Clinical Findings ◽

Imaging Features

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Renal cell carcinoma: Associations between tumor imaging features and epidemiological risk factors

European Journal of Radiology ◽

10.1016/j.ejrad.2020.109096 ◽

2020 ◽

Vol 129 ◽

pp. 109096

Author(s):

Andreas M. Hötker ◽

Christoph A. Karlo ◽

Pier Luigi Di Paolo ◽

Junting Zheng ◽

Chaya S. Moskowitz ◽

...

Keyword(s):

Risk Factors ◽

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Tumor Imaging ◽

Imaging Features ◽

Epidemiological Risk

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The potential in artificial intelligence-driven radiomic signature to predict survival in patients with metastatic colorectal cancer treated with cetuximab-based therapy.

Journal of Clinical Oncology ◽

10.1200/jco.2020.38.4_suppl.247 ◽

2020 ◽

Vol 38 (4_suppl) ◽

pp. 247-247

Author(s):

Laurent Dercle ◽

Lin Lu ◽

Lawrence Howard Schwartz ◽

Min Qian ◽

Sabine Tejpar ◽

...

Keyword(s):

Colorectal Cancer ◽

Cox Regression ◽

Tumor Imaging ◽

Roc Curves ◽

Standard Of Care ◽

Treatment Quality ◽

Ct Scans ◽

Imaging Features ◽

Data Set ◽

Mutational Status

247 Background: This analysis was undertaken to forecast survival and enhance treatment decisions for patients (pts) with colorectal cancer (CRC) with liver metastases sensitive to folinic acid, fluorouracil and irinotecan (FOLFIRI) alone [F] or in combination with cetuximab [FC] using simple quantitative radiomic changes between CT scans at baseline and 8 weeks. Methods: We retrospectively analyzed 667 pts with KRAS-unselected metastatic CRC in NCT00154102 treated with F and FC. CT quality was classified as high (HQ) or standard (SQ), and four data sets were created and named by treatment quality. Pts were randomly assigned 1:2 to training or validation sets: FCHQ, 38/78 pts; FCSQ, 62/124 pts; FHQ, 51/78 pts; FSQ, 78/158 pts. A machine-learning signature was trained using data set FCHQ to classify pts as treatment-sensitive or treatment-insensitive using just 4 of 3,499 potential radiomic imaging features. Performance was calibrated/validated using ROC curves. Hazard ratios (HRs) and Cox regression models were used to evaluate association with overall survival (OS). Results: The signature used decrease in tumor heterogeneity plus boundary infiltration to successfully predict sensitivity to FC (FCHQ: AUC, 0.80; FCSQ: AUC, 0.72) but failed with non-cetuximab regimens (FHQ: AUC, 0.59; FSQ: AUC, 0.55). The radiomic signature outperformed existing biomarkers ( KRAS mutational status and tumor shrinkage by RECIST 1.1) for sensitivity to cetuximab-based therapy and was strongly associated with OS in the cetuximab-containing sets FCHQ (HR, 44.3; p = 0.0001) and FCSQ (HR, 6.5; p = 0.005). Conclusions: This signature, derived from simple radiomic analysis of tumor imaging phenotype using only standard-of-care CT scans, appeared to be treatment-specific and was superior to all tested prognostic biomarkers. The signature provided early prediction of sensitivity and survival and could be used to guide treatment continuation decisions.

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