Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)

Mario E. Lacouture; John C. Morris; Donald P. Lawrence; Antoinette R. Tan; Thomas E. Olencki; Geoffrey I. Shapiro; Bruce J. Dezube; Jay A. Berzofsky; Frank J. Hsu; Joan Guitart

doi:10.1007/s00262-015-1653-0

Cutaneous keratoacanthomas/squamous cell carcinomas associated with neutralization of transforming growth factor β by the monoclonal antibody fresolimumab (GC1008)

Cancer Immunology Immunotherapy ◽

10.1007/s00262-015-1653-0 ◽

2015 ◽

Vol 64 (4) ◽

pp. 437-446 ◽

Cited By ~ 53

Author(s):

Mario E. Lacouture ◽

John C. Morris ◽

Donald P. Lawrence ◽

Antoinette R. Tan ◽

Thomas E. Olencki ◽

...

Keyword(s):

Monoclonal Antibody ◽

Growth Factor ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Squamous Cell Carcinomas

Download Full-text

Alterations of Transforming Growth Factor-β Signaling in Squamous Cell Carcinomas

Signaling Pathways in Squamous Cancer ◽

10.1007/978-1-4419-7203-3_3 ◽

2010 ◽

pp. 53-89 ◽

Cited By ~ 1

Author(s):

Wen Xie ◽

Michael Reiss

Keyword(s):

Growth Factor ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Squamous Cell Carcinomas

Download Full-text

Positive Transforming Growth Factor-β Activated Kinase-1 Expression Has an Unfavorable Impact on Survival in T3N1-3M0 Esophageal Squamous Cell Carcinomas

The Annals of Thoracic Surgery ◽

10.1016/j.athoracsur.2012.09.050 ◽

2013 ◽

Vol 95 (1) ◽

pp. 285-290 ◽

Cited By ~ 7

Author(s):

Jing Wen ◽

Yi Hu ◽

Kong-Jia Luo ◽

Hong Yang ◽

Shui-Shen Zhang ◽

...

Keyword(s):

Growth Factor ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Squamous Cell Carcinomas ◽

Impact On Survival ◽

Esophageal Squamous Cell Carcinomas

Download Full-text

Is the cellular location of transforming growth factor β receptors a key to biologic behavior of verrucous versus ordinary squamous cell carcinoma?

Advances in Anatomic Pathology ◽

10.1097/00125480-200007040-00016 ◽

2000 ◽

Vol 7 (4) ◽

pp. 256

Author(s):

&NA;

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Cell Carcinoma ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Cellular Location

Download Full-text

Loss of p12CDK2-AP1 Expression in Human Oral Squamous Cell Carcinoma with Disrupted Transforming Growth Factor-β-Smad Signaling Pathway

Neoplasia ◽

10.1593/neo.06580 ◽

2006 ◽

Vol 8 (12) ◽

pp. 1028-1036 ◽

Cited By ~ 21

Author(s):

Hui Peng ◽

Satoru Shintanit ◽

Yong Kim ◽

David T. Wong

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Signaling Pathway ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Smad Signaling ◽

Smad Signaling Pathway

Download Full-text

Transforming growth factor alpha expression helps to distinguish keratoacanthomas from squamous cell carcinomas

Archives of Dermatology ◽

10.1001/archderm.127.8.1167 ◽

1991 ◽

Vol 127 (8) ◽

pp. 1167-1171 ◽

Cited By ~ 7

Author(s):

T. Ho

Keyword(s):

Growth Factor ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Squamous Cell Carcinomas ◽

Transforming Growth Factor Alpha ◽

Factor Alpha

Download Full-text

Biological effects and binding properties of transforming growth factor-β on human oral squamous cell carcinoma cells

Experimental Cell Research ◽

10.1016/0014-4827(90)90090-w ◽

1990 ◽

Vol 187 (2) ◽

pp. 263-269 ◽

Cited By ~ 30

Author(s):

Hidenori Ichijo ◽

Fumio Momose ◽

Kohei Miyazono

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Biological Effects ◽

Transforming Growth Factor Β ◽

Carcinoma Cells ◽

Binding Properties

Download Full-text

237 Transforming Growth Factor-β and Notch1 Cooperate to Repress NOTCH3 to Facilitate Epithelial-Mesenchymal Transition and Tumor Initiating Capability in Esophageal Squamous Cell Carcinoma

Gastroenterology ◽

10.1016/s0016-5085(13)60183-3 ◽

2013 ◽

Vol 144 (5) ◽

pp. S-52

Author(s):

Mitsuteru Natsuizaka ◽

Shingo Kagawa ◽

Kelly A. Whelan ◽

Sanders Chang ◽

Hideaki Kinugasa ◽

...

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Esophageal Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Epithelial Mesenchymal Transition ◽

Transforming Growth Factor Β ◽

Mesenchymal Transition

Download Full-text

PREVENTION OF REJECTION OF TRANSFORMING GROWTH FACTOR β-TREATED RAT-TO-MOUSE ISLET XENOGRAFTS BY MONOCLONAL ANTIBODY TO TUMOR NECROSIS FACTOR

Transplantation Journal ◽

10.1097/00007890-199302000-00050 ◽

1993 ◽

Vol 55 (2) ◽

pp. 456 ◽

Cited By ~ 12

Author(s):

&NA;

Keyword(s):

Monoclonal Antibody ◽

Growth Factor ◽

Tumor Necrosis Factor ◽

Tumor Necrosis ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Mouse Islet ◽

Necrosis Factor

Download Full-text

Transforming Growth Factor β Receptors in Verrucous and Squamous Cell Carcinoma

Archives of Otolaryngology - Head and Neck Surgery ◽

10.1001/archotol.125.8.849 ◽

1999 ◽

Vol 125 (8) ◽

pp. 849 ◽

Cited By ~ 9

Author(s):

Meredith Anderson ◽

Carlos Muro-Cacho ◽

Joehassin Cordero ◽

Sandra Livingston ◽

Teresita Muñoz-Antonia

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Cell Carcinoma ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β

Download Full-text

Disruption of Transforming Growth Factor-β Signaling by Five Frequently Methylated Genes Leads to Head and Neck Squamous Cell Carcinoma Pathogenesis

Cancer Research ◽

10.1158/0008-5472.can-09-3073 ◽

2009 ◽

Vol 69 (24) ◽

pp. 9301-9305 ◽

Cited By ~ 21

Author(s):

Kristi L. Bennett ◽

Todd Romigh ◽

Charis Eng

Keyword(s):

Squamous Cell Carcinoma ◽

Growth Factor ◽

Cell Carcinoma ◽

Head And Neck ◽

Squamous Cell ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Neck Squamous Cell Carcinoma

Download Full-text