scholarly journals A Nested Case–Control Study on the Risk of Surgical Site Infection After Thyroid Surgery

2018 ◽  
Vol 42 (8) ◽  
pp. 2454-2461 ◽  
Author(s):  
F. A. Salem ◽  
M. Almquist ◽  
E. Nordenström ◽  
J. Dahlberg ◽  
O. Hessman ◽  
...  
2006 ◽  
Vol 27 (12) ◽  
pp. 1299-1303 ◽  
Author(s):  
Vicente Monge Jodra ◽  
Lourdes Sainz de los Terreros Soler ◽  
Cristina Díaz-Agero Pérez ◽  
Carmen María Saa Requejo ◽  
Nieves Plana Farrás

Objective. We estimated the impact of hip replacement-associated surgical site infection (SSI) on morbidity and length of stay. Methods. This was a pairwise matched (1 : 1) case-control study nested in a cohort. All patients who underwent hip replacement from January 1, 2000, to June 30, 2004, were prospectively enrolled for the nested case-control design analysis and were monitored from the time of surgery until hospital discharge, including any patients readmitted because of infection. Results. Among the 1,260 hip replacements performed, 28 SSIs were detected, yielding a crude SSI rate of 2.2%. The median excess length of stay attributable to SSI was 32.5 days (P< .001), whereas the median prolonged postoperative stay due to SSI was 31 days (P< .001). Deep-wound SSI was the type that prolonged hospital stay the most (up to 49 days). Of the patients who developed an SSI, 4 required revision surgery, for an SSI-related morbidity rate of 14.3%. Conclusion. SSI prolongs hospital stay; however, although hospital stay is a rough indicator of the cost of this complication, to accurately estimate the costs of SSI, we would need to consider individual costs in a linear regression model adjusted for all possible confounding factors.


2006 ◽  
Vol 27 (12) ◽  
pp. 1299-1303 ◽  
Author(s):  
Vicente Monge Jodra ◽  
Lourdes Sainz de los Terreros Soler ◽  
Cristina Díaz-Agero Pérez ◽  
Carmen María Saa Requejo ◽  
Nieves Plana Farrás

Objective.We estimated the impact of hip replacement-associated surgical site infection (SSI) on morbidity and length of stay.Methods.This was a pairwise matched (1 : 1) case-control study nested in a cohort. All patients who underwent hip replacement from January 1, 2000, to June 30, 2004, were prospectively enrolled for the nested case-control design analysis and were monitored from the time of surgery until hospital discharge, including any patients readmitted because of infection.Results.Among the 1,260 hip replacements performed, 28 SSIs were detected, yielding a crude SSI rate of 2.2%. The median excess length of stay attributable to SSI was 32.5 days (P< .001), whereas the median prolonged postoperative stay due to SSI was 31 days (P< .001). Deep-wound SSI was the type that prolonged hospital stay the most (up to 49 days). Of the patients who developed an SSI, 4 required revision surgery, for an SSI-related morbidity rate of 14.3%.Conclusion.SSI prolongs hospital stay; however, although hospital stay is a rough indicator of the cost of this complication, to accurately estimate the costs of SSI, we would need to consider individual costs in a linear regression model adjusted for all possible confounding factors.


2019 ◽  
Vol 47 (2) ◽  
pp. 164-169 ◽  
Author(s):  
Khalid BM Saeed ◽  
Paul Corcoran ◽  
Mairead O'Riordan ◽  
Richard A. Greene

2016 ◽  
Vol 135 (S1) ◽  
pp. S107-S110 ◽  
Author(s):  
Boezemwendé Kaboré ◽  
Georges Soudouem ◽  
Ibrahima Seck ◽  
Tieba Millogo ◽  
Wambi Maurice Evariste Yaméogo ◽  
...  

2019 ◽  
Vol 404 (7) ◽  
pp. 815-823
Author(s):  
Farhad Allahyar Salem ◽  
A. Bergenfelz ◽  
E. Nordenström ◽  
J. Dahlberg ◽  
O. Hessman ◽  
...  

Abstract Purpose Postoperative bleeding after thyroid surgery remains a potentially lethal complication. Outpatient thyroidectomy is an increasing trend in the high volume centers. There is a need to identify risk factors for postoperative bleeding in order to select proper patients for outpatient thyroidectomy. This study aimed to investigate this issue using a national population-based register. Material and method A nested case-control study on patients registered in the Swedish national register for endocrine surgery (SQRTPA) was performed. Patients with postoperative bleeding were matched 1:1 by age and gender to controls. Additional information on cases and controls was obtained from attending surgeons using a questionnaire. Risk factors for postoperative bleeding were evaluated with logistic regression and are presented as odds ratios (ORs) with 95% confidence intervals (CIs). The time of bleeding in relation to surgery was also investigated. Results There were 9494 operations, and 174 (1.8%) of them involved postoperative bleeding. In the whole cohort, patients with postoperative bleeding were older, 58 (46–69) vs. 49 (37–62) years, than patients without, p < 0.01. Male patients had a higher risk of bleeding, OR 2.18 (95% CI 1.58–2.99). In the case-control cohort, drain was an independent risk factor for bleeding, OR 1.64 (1.05–2.57). Two-thirds of patients bled within 6 h after surgery. The incidence of bleeding after 24 h was 10%. Conclusion High age, male gender, and drain are independent risk factors for bleeding after thyroid surgery. Even with careful patient selection, prolonged observation might be necessary in thyroid surgery.


2014 ◽  
Vol 35 (12) ◽  
pp. 1535-1538 ◽  
Author(s):  
Heather L. Young ◽  
Sara Reese ◽  
Bryan Knepper ◽  
Amber Miller ◽  
Cyril Mauffrey ◽  
...  

Skin preparation products contribute to surgical site infection (SSI) prevention. In a case-control study, diabetes was associated with increased SSI (adjusted odds ratio [OR], 5.74 [95% confidence interval (CI), 1.22–27.0]), while the use of chlorhexidine gluconate (CHG) plus isopropyl alcohol versus CHG alone was found to be protective (adjusted OR, 2.64 [95% CI, 1.12–6.20]).Infect Control Hosp Epidemiol 2014;35(12):1535–1538


2006 ◽  
Vol 134 (6) ◽  
pp. 1167-1173 ◽  
Author(s):  
D. CARNICER-PONT ◽  
K. A. BAILEY ◽  
B. W. MASON ◽  
A. M. WALKER ◽  
M. R. EVANS ◽  
...  

A case-control study was undertaken in an acute district general hospital to identify risk factors for hospital-acquired bacteraemia caused by methicillin-resistant Staphylococcus aureus (MRSA). Cases of hospital-acquired MRSA bacteraemia were defined as consecutive patients from whom MRSA was isolated from a blood sample taken on the third or subsequent day after admission. Controls were randomly selected from patients admitted to the hospital over the same time period with a length of stay of more than 2 days who did not have bacteraemia. Data on 42 of the 46 cases of hospital-acquired bacteraemia and 90 of the 92 controls were available for analysis. There were no significant differences in the age or sex of cases and controls. After adjusting for confounding factors, insertion of a central line [adjusted odds ratio (aOR) 35·3, 95% confidence interval (CI) 3·8–325·5] or urinary catheter (aOR 37·1, 95% CI 7·1–193·2) during the admission, and surgical site infection (aOR 4·3, 95% CI 1·2–14·6) all remained independent risk factors for MRSA bacteraemia. The adjusted population attributable fraction, showed that 51% of hospital-acquired MRSA bacteraemia cases were attributable to a urinary catheter, 39% to a central line, and 16% to a surgical site infection. In the United Kingdom, measures to reduce the incidence of hospital-acquired MRSA bacteraemia in acute general hospitals should focus on improving infection control procedures for the insertion and, most importantly, care of central lines and urinary catheters.


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