Risk Factors Associated with In-Hospital Mortality for Patients with Acute Abdomen After Cardiac Surgery

2019 ◽  
Vol 44 (1) ◽  
pp. 277-284
Author(s):  
I. Djordjevic ◽  
K. Eghbalzadeh ◽  
S. Heinen ◽  
G. Schlachtenberger ◽  
S. Gerfer ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Hospital Mortality ◽  
Acute Abdomen ◽  
Factors Associated

scholarly journals Risk Factors Associated with In-hospital Mortality for Patients with Acute Abdomen after Cardiac Surgery

2019 ◽  
Author(s):  
I. Djordjevic ◽  
K. Eghbalzadeh ◽  
S. Heinen ◽  
G. Schlachtenberger ◽  
C. Weber ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Hospital Mortality ◽  
Acute Abdomen ◽  
Factors Associated

Risk Factors for the Development of Nosocomial Pneumonia and Its Clinical Impact in Cardiac Surgery

2021 ◽  
Author(s):  
Ferdinand Jr Rivera Gerod ◽  
Edgar Ongjoco ◽  
Rod Castro ◽  
Armin Masbang ◽  
Elmer Casley Repotente ◽  
...  
Keyword(s):  
Risk Factors ◽  
Mechanical Ventilation ◽  
Cardiac Surgery ◽  
Hospital Mortality ◽  
Nosocomial Pneumonia ◽  
Clinical Impact ◽  
Adult Patients ◽  
Mortality And Morbidity ◽  
Factors Associated ◽  
Prolonged Icu Stay

Abstract BackgroundThe development of nosocomial pneumonia after cardiac surgery is a significant post-operative complication that may lead to increased morbidity, mortality, and hospital cost. We aimed to identify risk factors associated with it and to determine its clinical impact in terms of in-hospital mortality and morbidity.MethodsThis is a retrospective cohort study conducted among all adult patients who underwent cardiac surgery from 2014-2019 in St. Luke’s Medical Center, Quezon City, Philippines. Baseline characteristics and possible risk factors for pneumonia were retrieved from medical records. Nosocomial pneumonia was based on the Centers for Disease Control and Prevention criteria. Clinical outcomes include in-hospital mortality and morbidity. Odds ratios from logistic regression was computed to determine risk factors associated with pneumonia using STATA 15.0.ResultsOut of 373 patients included in this study, 104 (28%) patients acquired pneumonia. Most surgeries were coronary artery bypass graft (CABG) (71.58%), followed by valve repair/replacement (29.76%). Neither age, sex, BMI, diabetes, LV dysfunction, renal dysfunction, COPD/asthma, urgency of surgery, surgical time, nor smoking showed association in the development of pneumonia. However, preoperative stay of >2 days was associated with 92.3% (95%CI 18–213%) increased odds of having pneumonia (p=.009). Also, every additional hour on mechanical ventilation conferred 0.8% (95%CI, 0.3–1%) greater odds of acquiring pneumonia (p=.003).Patients who developed pneumonia had 3.9 times odds of mortality (95%CI 1.51–9.89, p=.005), 3.8 times odds of prolonged hospitalization (95%CI 1.81–7.90,p<.001), 6.4 times odds of prolonged ICU stay (95%CI 3.59–11.35,p<.001), and 9.5 times odds of postoperative reintubation (95%CI 3.01–29.76,p<.001). ConclusionAmong adult patients undergoing cardiac surgeries, prolonged preoperative hospital stay and prolonged mechanical ventilation were both associated with an increased risk for nosocomial pneumonia. Those who developed pneumonia had worse outcomes with significantly increased in-hospital mortality, prolonged hospitalization, prolonged ICU stay, and increased postoperative re-intubation. Clinicians should therefore minimize delays in surgery to avoid unnecessary exposure to pathogenic organisms. Also, timely liberation from mechanical ventilation after surgery should be encouraged.

scholarly journals Frequency of renal dysfunction in cardiac surgery patients and its effect on outcome

2018 ◽  
pp. 40-47
Author(s):  
K. Zakon ◽  
V. Romanova ◽  
K. Tverdohlib
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Statistical Analysis ◽  
Hospital Mortality ◽  
Renal Dysfunction ◽  
Postoperative Period ◽  
Significant Risk ◽  
Multiorgan Dysfunction ◽  
Factors Associated ◽  
Multiorgan Dysfunction Syndrome

The purpose of this study was to define the frequency of renal dysfunction, including acute kidney injury (AKI), in cardiac surgery patients and its effect on outcome. Materials and methods. Patients 18 years old or older underwent cardiac surgery were included in the study. AKI and chronic kidney disease (CKD) was defined and staged according KDIGO 2012 guidelines. Glomerular filtration rate (GFR) was calculated with CKD-EPI formula. Clinical, laboratory and instrumental investigations were performed to all patients. As well, continuous hemodynamic monitoring was performed in postoperative period. Statistical analysis was conducted with SPSS for Windows v. 17.0.0. Results. 239 patients (170 (72,8 %) – male, 65 (27,2 %) – female) underwent cardiac surgery in M.M. Amosov National Institute of Cardio-Vascular Surgery between 29.06.16 and 30.10.16 were included in the study.             79 patients had a renal dysfunction before surgery: 19 (7.9%) – CKD and 60 (25.1%) – AKI. Renal replacement therapy (RRT) was used in 7 patients (4 — with CKD and 3 — with AKI). AKI was developed in 38 patients (15.9%) in postoperative period and RRT was started in one case. Statistically significant risk factors associated with AKI development in postoperative period were epinephrine usage (р<0.05) and heart failure development (р<0,001). Hospital mortality was 5.9% - 14 patients (7 (50%) - male, 7 (50 %) - female). All died patients have had renal dysfunction (3 (21.4%) have had AKI on CKD and 11 (78.6%) — AKI). Among them 8 (57.1%) patients have had AKI I, 1 (7.1%) - AKI II and 5 (35.7%) - AKI III. Statistically significant risk factors associated with hospital death were multiorgan dysfunction syndrome (р<0.001), sepsis (р<0.001), epinephrine (р<0.001) and norepinehrine (р<0.001) usage. Dobutamine use was associated with significant improvement in hospital mortality (р<0.05). Conclusions: Near half of cardiac surgery patients had renal dysfunction in perioperative period. RRT was used in 3.4% patients. Because the majority of died patients have had the first stage of AKI, which rather means the risk of renal dysfunction, and statistical analysis reveals no significant association between renal function and outcome, developing of AKI in cardiac surgery patients is an indicator of severity of main disease, but not a cause of death. Renal dysfunction regardless of time of it development in relation to cardiac surgery is not risk factor of death, in contrast to multiorgan dysfunction syndrome and sepsis,  which warrant the use of epinephrine.

Risk factors associated with post-operative bleeding in patients undergoing cardiac surgery

2021 ◽  
Vol 23 ◽  
pp. 100158
Author(s):  
Yazmín Guillén Dolores ◽  
Carlos Alberto Delgado Quintana ◽  
Gustavo Lugo Goytia
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Factors Associated

Risk factors associated with cardiac surgery during pregnancy

2003 ◽  
Vol 76 (5) ◽  
pp. 1605-1608 ◽  
Author(s):  
Renato T Arnoni ◽  
Antoninho S Arnoni ◽  
Rômulo C.A Bonini ◽  
Antônio F.S de Almeida ◽  
Camilo A Neto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Factors Associated

373 Risk factors associated with recurrent seizures following cardiac surgery

2011 ◽  
Vol 27 (5) ◽  
pp. S195-S196
Author(s):  
R.A. Manji ◽  
H.P. Grocott ◽  
A.H. Menkis ◽  
E. Jacobsohn
Keyword(s):  
Risk Factors ◽  
Cardiac Surgery ◽  
Factors Associated

scholarly journals Mortality Predictors in Severe COVID-19 Patients from an East European Tertiary Center: A Never-Ending Challenge for a No Happy Ending Pandemic

2021 ◽  
Vol 11 (1) ◽  
pp. 58
Author(s):  
Amalia-Stefana Timpau ◽  
Radu-Stefan Miftode ◽  
Antoniu Octavian Petris ◽  
Irina-Iuliana Costache ◽  
Ionela-Larisa Miftode ◽  
...  
Keyword(s):  
Risk Factors ◽  
Hospital Mortality ◽  
Poor Prognosis ◽  
Survival Rates ◽  
C Reactive Protein ◽  
Happy Ending ◽  
Factors Associated ◽  
Reactive Protein ◽  
Tertiary Center ◽  
D Dimer

(1) Background: There are limited clinical data in patients from the Eastern European regions hospitalized for a severe form of Coronavirus disease 2019 (COVID-19). This study aims to identify risk factors associated with intra-hospital mortality in patients with COVID-19 severe pneumonia admitted to a tertiary center in Iasi, Romania. (2) Methods: The study is of a unicentric retrospective observational type and includes 150 patients with severe COVID-19 pneumonia divided into two subgroups, survivors and non-survivors. Demographic and clinical parameters, as well as comorbidities, laboratory and imaging investigations upon admission, treatments, and evolution during hospitalization were recorded. First, we sought to identify the risk factors associated with intra-hospital mortality using logistic regression. Secondly, we assessed the correlations between D-Dimer and C-reactive protein and predictors of poor prognosis. (3) Results: The predictors of in-hospital mortality identified in the study are D-dimers >0.5 mg/L (p = 0.002), C-reactive protein >5mg/L (p = 0.001), and heart rate above 100 beats per minute (p = 0.001). The biomarkers were also significantly correlated the need for mechanical ventilation, admission to intensive care unit, or multiple organ dysfunction syndrome. By area under the curve (AUC) analysis, we noticed that both D-Dimer (AUC 0.741) and C-reactive protein (AUC 0.707) exhibit adequate performance in predicting a poor prognosis in patients with severe viral infection. (4) Conclusions: COVID-19′s outcome is significantly influenced by several laboratory and clinical factors. As mortality induced by severe COVID-19 pneumonia is considerable, the identification of risk factors associated with negative outcome coupled with an early therapeutic approach are of paramount importance, as they may significantly improve the outcome and survival rates.

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