Pain Relief Following Percutaneous Vertebroplasty: Results of a Series of 283 Consecutive Patients Treated in a Single Institution

2007 ◽  
Vol 30 (3) ◽  
pp. 441-447 ◽  
Author(s):  
Giovanni Carlo Anselmetti ◽  
Giovanni Corrao ◽  
Patrizia Della Monica ◽  
Vincenzo Tartaglia ◽  
Antonio Manca ◽  
...  
Keyword(s):  
Pain Relief ◽  
Percutaneous Vertebroplasty ◽  
Single Institution

Percutaneous Vertebroplasty for Pain Relief and Spinal Stabilization

Spine ◽  
2000 ◽  
Vol 25 (8) ◽  
pp. 923-928 ◽  
Author(s):  
John D. Barr ◽  
Michelle S. Barr ◽  
Thomas J. Lemley ◽  
Richard M. McCann
Keyword(s):  
Pain Relief ◽  
Percutaneous Vertebroplasty ◽  
Spinal Stabilization

Dose-dependent epidural leakage of polymethylmethacrylate after percutaneous vertebroplasty in patients with osteoporotic vertebral compression fractures

2002 ◽  
Vol 96 (1) ◽  
pp. 56-61 ◽  
Author(s):  
Kyung Sik Ryu ◽  
Chun Kun Park ◽  
Moon Chan Kim ◽  
Joon Ki Kang
Keyword(s):  
Pain Relief ◽  
Epidural Space ◽  
Percutaneous Vertebroplasty ◽  
Vertebral Compression Fractures ◽  
Osteoporotic Vertebral Compression Fractures ◽  
Content Type ◽  
Compression Fractures ◽  
Dose Dependent ◽  
Pmma Cement ◽  
Fine Print

Object. The use of polymethylmethacrylate (PMMA) cement by percutaneous injection in cases requiring vertebroplasty provides pain relief in the treatment of osteoporotic vertebral compression fractures. A retrospective study was performed to assess what caused PMMA cement to leak into the epidural space and to determine if this leakage caused any changes in its therapeutic benefits. Methods. Polymethylmethacrylate was injected into 347 vertebral compression fractures in 159 patients. The cement leaked into the epidural space in 92 (26.5%) of 347 treated vertebrae in 64 (40.3%) of the 159 patients, as demonstrated on postoperative computerized tomography scanning. Epidural leakage of PMMA cement occurred more often when injected above the level of T-7 (p = 0.001) than below. The larger the volume of PMMA injected the higher the incidence of epidural leakage (p = 0.03). Using an injector also increased epidural leakage (p = 0.045). The position of the needle tip within the vertebral body and the pattern of venous drainage did not affect epidural leakage of the cement. Leakage of PMMA into the epidural space reduced the pain relief expected after vertebroplasty. The immediate postoperative visual analog scale scores were higher (and therefore reflective of less pain relief) in patients in whom epidural PMMA leakage occurred (p = 0.009). Three months postoperatively, the authors found the highest number of patients presenting with pain relief, including those in the group with epidural leakage, and at this follow-up stage there were no significant differences between the two groups. Conclusions. The authors found that epidural leakage of PMMA after percutaneous vertebroplasty was dose dependent. The larger amount of injected PMMA, the higher the incidence of leakage. Injecting vertebral levels above T-7 also increased the incidence of epidural leakage. Epidural leakage of PMMA may attenuate only the immediate therapeutic effects of vertebroplasty.

Efficacy of percutaneous vertebroplasty combined with radiotherapy in osteolytic metastatic spinal tumors

2005 ◽  
Vol 2 (3) ◽  
pp. 243-248 ◽  
Author(s):  
Jee-Soo Jang ◽  
Sang-Ho Lee
Keyword(s):  
Pain Relief ◽  
Percutaneous Vertebroplasty ◽  
Invasive Procedure ◽  
Spinal Tumors ◽  
Percutaneous Injection ◽  
Content Type ◽  
Spinal Stabilization ◽  
Before And After ◽  
Fine Print

Object. Vertebroplasty involves the percutaneous injection of polymethylmethacrylate into collapsed vertebral bodies due to hemangioma, osteoporosis, or malignant tumor. The purpose of this study was to evaluate the merits and efficacy of percutaneous vertebroplasty (PVP) combined with radiotherapy in treating patients with osteolytic metastatic spinal tumors (OMSTs). Methods. Twenty-eight patients with OMSTs underwent PVP for the treatment of 72 vertebrae after administration of a local anesthetic or induction of general anesthesia for pain relief and spinal stabilization. Radiotherapy for suppressing tumor or inducing pain relief was performed immediately after PVP in 22 patients. Pain levels were assessed before and after the procedure by using a visual analog scale (VAS), and follow-up assessment was conducted at 1, 3, 6, and 9 months. On postoperative Day 3, marked-to-complete VAS score—based pain relief was achieved in 13 patients (48%) and moderate relief was demonstrated in 11 (41%). The mean VAS pain score was reduced from 8.2 to 3, and major complications were absent in all cases. Follow-up plain radiography was performed to assess vertebral column stability. Neither additional vertebral collapse in the treated vertebrae nor neurological deterioration was observed. Conclusions. Percutaneous vertebroplasty is a minimally invasive procedure and, when combined with radiotherapy, seems to be effective in providing pain relief and stabilization in patients with OMSTs.

scholarly journals Percutaneous Vertebroplasty for Tumoral Fractures

2018 ◽  
Vol 24 (4) ◽  
pp. 293-299
Author(s):  
Ana Paula Narata ◽  
Olivier Brina ◽  
Denis Herbretau ◽  
Jean-Philippe Cottier ◽  
Pierre-Yves Dietrich ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Pain Management ◽  
Pain Relief ◽  
Bone Metastases ◽  
Systemic Therapy ◽  
Multidisciplinary Team ◽  
Multidisciplinary Approach ◽  
Percutaneous Vertebroplasty ◽  
Percutaneous Procedures ◽  
Oncologic Patients

The pain management in oncologic patients requires a multidisciplinary approach. Considering bone metastases, multiple myeloma and lymphoma, percutaneous procedures like vertebroplasty can provide rapid pain relief. However, percutaneous vertebroplasty must be placed in order to not delay systemic therapy or other modalities of treatment. In this article, we described our 15 years’ experience in collaborating with a multidisciplinary team, reviewing literature and special issues percutaneous vertebroplasty for spinal tumoral fractures.

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