Role of NADPH cytochrome P450 reductase in activation of RH1

Asher Begleiter; Marsha K. Leith; Daywin Patel; Brian B. Hasinoff

doi:10.1007/s00280-007-0417-8

Role of NADPH cytochrome P450 reductase in activation of RH1

Cancer Chemotherapy and Pharmacology ◽

10.1007/s00280-007-0417-8 ◽

2007 ◽

Vol 60 (5) ◽

pp. 713-723 ◽

Cited By ~ 13

Author(s):

Asher Begleiter ◽

Marsha K. Leith ◽

Daywin Patel ◽

Brian B. Hasinoff

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Probing the role of lysines and arginines in the catalytic function of cytochrome P450d by site-directed mutagenesis. Interaction with NADPH-cytochrome P450 reductase

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)67801-4 ◽

1991 ◽

Vol 266 (6) ◽

pp. 3372-3375

Author(s):

T Shimizu ◽

T Tateishi ◽

M Hatano ◽

Y Fujii-Kuriyama

Keyword(s):

Cytochrome P450 ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Catalytic Function ◽

Nadph Cytochrome P450 Reductase

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Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase. Implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells

Anti-Cancer Drugs ◽

10.1097/cad.0b013e32834fcf4f ◽

2012 ◽

Vol 23 (4) ◽

pp. 393-405 ◽

Cited By ~ 5

Author(s):

Dorota Kostrzewa-Nowak ◽

Bohdan Bieg ◽

Mark J.I. Paine ◽

C. Roland Wolf ◽

Jolanta Tarasiuk

Keyword(s):

Cytochrome P450 ◽

Multidrug Resistant ◽

Structural Factors ◽

Cytochrome P450 Reductase ◽

Hl60 Cells ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anthraquinone Derivatives ◽

Nadph Cytochrome P450 Reductase

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Role of the prosthetic groups of NADPH-cytochrome P450 reductase in 3-hydroxyanthranilamide-catalyzed, NADPH-dependent superoxide anion production

Redox Report ◽

10.1080/13510002.1996.11747070 ◽

1996 ◽

Vol 2 (5) ◽

pp. 339-344

Author(s):

Y. Ohta ◽

R. Shinohara ◽

I. Ishiguro

Keyword(s):

Cytochrome P450 ◽

Superoxide Anion ◽

Cytochrome P450 Reductase ◽

Superoxide Anion Production ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Anion Production ◽

Nadph Cytochrome P450 Reductase ◽

Prosthetic Groups

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Role of LYS271 and LYS279 Residues in the Interaction of Cytochrome P4501A1 with NADPH–Cytochrome P450 Reductase

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.2000.2174 ◽

2001 ◽

Vol 385 (2) ◽

pp. 290-300 ◽

Cited By ~ 9

Author(s):

Tomas Cvrk ◽

Henry W. Strobel

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Cytochrome P4501a1 ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Role of human cytochrome P450 (CYP) in the metabolic activation of N-alkylnitrosamines: application of genetically engineered Salmonella typhimurium YG7108 expressing each form of CYP together with human NADPH-cytochrome P450 reductase

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis ◽

10.1016/s0027-5107(01)00223-8 ◽

2001 ◽

Vol 483 (1-2) ◽

pp. 35-41 ◽

Cited By ~ 40

Author(s):

Ken-ichi Fujita ◽

Tetsuya Kamataki

Keyword(s):

Cytochrome P450 ◽

Salmonella Typhimurium ◽

Metabolic Activation ◽

Genetically Engineered ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Human Cytochrome ◽

Nadph Cytochrome P450 Reductase

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The role of cytochrome P450 lysine residues in the interaction between cytochrome P450IA1 and NADPH-cytochrome P450 reductase

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(92)90140-r ◽

1992 ◽

Vol 294 (1) ◽

pp. 83-90 ◽

Cited By ~ 29

Author(s):

Sijiu Shen ◽

Henry W. Strobel

Keyword(s):

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Lysine Residues ◽

Nadph Cytochrome P450 Reductase

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The Optical Biosensor Studies on the Role of Hydrophobic Tails of NADPH-Cytochrome P450 Reductase and Cytochromes P450 2B4 and b5 upon Productive Complex Formation within a Monomeric Reconstituted System

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1998.0981 ◽

1999 ◽

Vol 362 (1) ◽

pp. 87-93 ◽

Cited By ~ 33

Author(s):

Yuri D. Ivanov ◽

Irina P. Kanaeva ◽

Vadim Yu. Kuznetsov ◽

Michael Lehnerer ◽

Johannes Schulze ◽

...

Keyword(s):

Cytochrome P450 ◽

Complex Formation ◽

Cytochromes P450 ◽

Optical Biosensor ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Reconstituted System ◽

Nadph Cytochrome P450 Reductase

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Correction: The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength

Frontiers in Pharmacology ◽

10.3389/fphar.2018.00175 ◽

2018 ◽

Vol 9 ◽

Author(s):

Diana Campelo ◽

Thomas Lautier ◽

Philippe Urban ◽

Francisco Esteves ◽

Sophie Bozonnet ◽

...

Keyword(s):

Cytochrome P450 ◽

Ionic Strength ◽

Critical Role ◽

Cytochrome P450 Reductase ◽

Conformational Switching ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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Microsomal lipid peroxidation: The role of NADPH — Cytochrome P450 reductase and cytochrome P450

Free Radical Biology and Medicine ◽

10.1016/0891-5849(90)90087-y ◽

1990 ◽

Vol 8 (2) ◽

pp. 145-152 ◽

Cited By ~ 70

Author(s):

Alex Sevanian ◽

Kerstin Nordenbrand ◽

Eunjoo Kim ◽

Lars Ernster ◽

Paul Hochstein

Keyword(s):

Lipid Peroxidation ◽

Cytochrome P450 ◽

Cytochrome P450 Reductase ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Microsomal Lipid Peroxidation ◽

Nadph Cytochrome P450 Reductase

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The Hinge Segment of Human NADPH-Cytochrome P450 Reductase in Conformational Switching: The Critical Role of Ionic Strength

Frontiers in Pharmacology ◽

10.3389/fphar.2017.00755 ◽

2017 ◽

Vol 8 ◽

Cited By ~ 12

Author(s):

Diana Campelo ◽

Thomas Lautier ◽

Philippe Urban ◽

Francisco Esteves ◽

Sophie Bozonnet ◽

...

Keyword(s):

Cytochrome P450 ◽

Ionic Strength ◽

Critical Role ◽

Cytochrome P450 Reductase ◽

Conformational Switching ◽

Nadph Cytochrome ◽

P450 Reductase ◽

Nadph Cytochrome P450 Reductase

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