Correction to: Radiomics score predicts acute respiratory distress syndrome based on the initial CT scan after trauma

Background Coronavirus disease 2019 (COVID-19) is a serious illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and in severe cases associated with acute respiratory distress syndrome (ARDS). Objective To describe the clinical characteristics of patients with ARDS-COVID-19. Materials and methods This study involved 197 male Egyptian participants, among them111 COVID-19 patients presented with ARDS, 60 COVID-19 patients presented with non-ARDS, and 26 Non-COVID-19 patients. We reported the analysis results of clinical and laboratory information, including blood routine tests, blood biochemistry parameters [aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine and C‐reactive protein (CRP)], thrombotic activity (D‐dimer) and serum ferritin and lactate dehydrogenase (LDH). Results The levels of hemoglobin, AST, creatinine, monocyte count, monocyte %, RBC count, TLC, and platelet count were not significantly different among the groups. The lymphopenia and increased CRP, ALT, D-dimer, ferritin, and LDH were observed in patients with ARDS-COVID-19. Conclusion COVID-19 patients with ARDS presented with lymphopenia, increased thrombotic activity, increased CRP, LDH, and ferritin levels. The results revealed that CRP, D-dimer, LDH levels, and lymphopenia have a significant association with the COVID-19 severity and can be used as biomarkers to predict the disease severity.

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CT-scan lung morphology predicts the response to a recruitment maneuver in acute respiratory distress syndrome patients

Critical Care ◽

10.1186/cc7204 ◽

2009 ◽

Vol 13 (Suppl 1) ◽

pp. P40 ◽

Cited By ~ 1

Author(s):

J Constantin ◽

S Grasso ◽

JJ Rouby ◽

E Futier ◽

B Gallix ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Ct Scan ◽

Distress Syndrome ◽

Recruitment Maneuver ◽

Lung Morphology

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Assessment of Lung Aeration and Recruitment by CT Scan and Ultrasound in Acute Respiratory Distress Syndrome Patients*

Critical Care Medicine ◽

10.1097/ccm.0000000000003340 ◽

2018 ◽

Vol 46 (11) ◽

pp. 1761-1768 ◽

Cited By ~ 53

Author(s):

Davide Chiumello ◽

Silvia Mongodi ◽

Ilaria Algieri ◽

Giordano Luca Vergani ◽

Anita Orlando ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Ct Scan ◽

Distress Syndrome ◽

Lung Aeration

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Evolution of chest CT scan manifestations in a patient recovered from COVID-19 severe pneumonia with acute respiratory distress syndrome

Respiratory Medicine Case Reports ◽

10.1016/j.rmcr.2021.101342 ◽

2021 ◽

Vol 32 ◽

pp. 101342

Author(s):

Daniel Maranatha ◽

Paulus Rahardjo ◽

Rikky Lusman

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Ct Scan ◽

Distress Syndrome ◽

Severe Pneumonia ◽

Chest Ct ◽

Chest Ct Scan

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The Role of CT-scan Studies for the Diagnosis and Therapy of Acute Respiratory Distress Syndrome

Clinics in Chest Medicine ◽

10.1016/j.ccm.2006.06.002 ◽

2006 ◽

Vol 27 (4) ◽

pp. 559-570 ◽

Cited By ~ 60

Author(s):

Luciano Gattinoni ◽

Pietro Caironi ◽

Franco Valenza ◽

Eleonora Carlesso

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Ct Scan ◽

Distress Syndrome ◽

Diagnosis And Therapy

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Effect of early treatment with polyvalent immunoglobulin on acute respiratory distress syndrome associated with SARS-CoV-2 infections (ICAR trial): study protocol for a randomized controlled trial

Trials ◽

10.1186/s13063-021-05118-7 ◽

2021 ◽

Vol 22 (1) ◽

Author(s):

Aurélien Mazeraud ◽

Bruno Gonçalves ◽

Philippe Aegerter ◽

Letizia Mancusi ◽

Christine Rieu ◽

...

Keyword(s):

Mechanical Ventilation ◽

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Organ Failure ◽

Daily Living ◽

Distress Syndrome ◽

Phase Iii ◽

Link Type ◽

Polyvalent Immunoglobulin

Abstract Background As of mid-June 2020, 7,500,000 people were infected with SARS-CoV-2 worldwide and 420,000 people died, mainly from coronavirus disease 2019 (COVID-19)-related acute respiratory distress syndrome (ARDS). COVID-19-related ARDS is subject to a mortality rate of 50% and prolonged period of mechanical ventilation, with no specific pharmacological treatment currently available (Infection au nouveau Coronavirus (SARS-CoV-2), COVID-19, France et Monde. https://www.santepubliquefrance.fr/dossiers/coronavirus-covid-19). Because of its immunomodulatory action, we propose to evaluate the efficacy and safety of intravenous immunoglobulin (IVIG) administration in patients developing COVID-19-related ARDS. Methods The trial is a phase III double-blind, randomized, multicenter, parallel group, concurrent, controlled study in hospitalized participants with COVID-19 requiring mechanical ventilation using a sequential design. Participants in the treatment group will receive infusions of polyvalent immunoglobulin for 4 consecutive days, and the placebo group will receive an equivalent volume of sodium chloride 0.9% for the same duration. The primary outcome is the number of ventilator-free days up to the 28th day. Secondary objectives are to evaluate the effect of IVIG on (1) organ failure according to the Sequential Organ Failure Assessment (SOFA) score at 14 and 28 days, (2) lung injury score at 14 and 28 days, (3) the occurrence of grade 3 or 4 adverse events of IVIG, (4) length of intensive care unit (ICU) stay, (5) length of hospital stay, (6) functional outcomes at day 90 defined by the activities of daily living and instrumental activities of the daily living scales, and (7) 90-day survival. One hundred thirty-eight subjects will be randomized in a 1:1 ratio to IVIG or placebo groups (69 in each group), considering 90% power, alpha level 0.05 (two sides), and 0.67 effect size level. Discussion The ICAR trial investigates the effect of IVIG in COVID-19-related ARDS. We expect an increase in the survival rate and a reduction in the duration of mechanical ventilation, which is associated with significant morbidity. Trial registration EudraCT 2020-001570-30. ClinicalTrials.gov NCT04350580. Registered on 17 April 2020

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Hysteresis and Lung Recruitment in Acute Respiratory Distress Syndrome Patients: A CT Scan Study*

Critical Care Medicine ◽

10.1097/ccm.0000000000004518 ◽

2020 ◽

Vol 48 (10) ◽

pp. 1494-1502 ◽

Cited By ~ 1

Author(s):

Davide Chiumello ◽

Jean-Michel Arnal ◽

Michele Umbrello ◽

Antonio Cammaroto ◽

Paolo Formenti ◽

...

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Ct Scan ◽

Distress Syndrome ◽

Lung Recruitment

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Therapeutic Evaluation of Computed Tomography Findings for Efficacy of Prone Ventilation in Acute Respiratory Distress Syndrome Patients with Abdominal Surgery

The Journal of Critical Care Medicine ◽

10.2478/jccm-2020-0003 ◽

2020 ◽

Vol 6 (1) ◽

pp. 32-40 ◽

Cited By ~ 4

Author(s):

Masayuki Akatsuka ◽

Hiroomi Tatsumi ◽

Naoya Yama ◽

Yoshiki Masuda

Keyword(s):

Acute Respiratory Distress Syndrome ◽

Abdominal Surgery ◽

Respiratory Distress Syndrome ◽

Respiratory Distress ◽

Ct Scan ◽

Distress Syndrome ◽

Ground Glass Opacity ◽

Ct Scanning ◽

Group A ◽

Group B

AbstractIntroductionIn Acute Respiratory Distress Syndrome (ARDS), the heterogeneity of lung lesions results in a mis-match between ventilation and perfusion, leading to the development of hypoxia. The study aimed to examine the association between computed tomographic (CT scan) lung findings in patients with ARDS after abdominal surgery and improved hypoxia and mortality after prone ventilation.Material and MethodsA single site, retrospective observational study was performed at the Sapporo Medical University School of Medicine, Sapporo, Hokkaido, Japan, between 1st January 2004 and 31st October 2018. Patients were allocated to one of two groups after CT scanning according to the presence of ground-glass opacity (GGO) or alveolar shadow with predominantly dorsal lung atelectasis (DLA) on lung CT scan images. Also, Patients were divided into a prone ventilation group and a supine ventilation group when the treatment for ARDS was started.ResultsWe analyzed data for fifty-one patients with ARDS following abdominal surgery. CT scans confirmed GGO in five patients in the Group A and in nine patients in the Group B, and DLA in 17 patients in the Group A and nine patients in the Group B. Both GGO and DLA were present in two patients in the Group A and nine patients in the Group B. Prone ventilation significantly improved patients’ impaired ratio of arterial partial pressure of oxygen to fraction of inspired oxygen from 12 h after prone positioning compared with that in the supine position. Weaning from mechanical ventilation occurred significantly earlier in the Group A with DLA vs the Group B with DLA (P < 0.001). Twenty-eight-day mortality was significantly lower for the Group A with DLA vs the Group B with DLA (P = 0.035).ConclusionsThese results suggest that prone ventilation could be effective for treating patients with ARDS as showing the DLA.

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