Role of imaging and biopsy to assess local recurrence after definitive treatment for prostate carcinoma (surgery, radiotherapy, cryotherapy, HIFU)

2011 ◽  
Vol 29 (5) ◽  
pp. 595-605 ◽  
Author(s):  
Pasquale Martino ◽  
Vincenzo Scattoni ◽  
Andrea B. Galosi ◽  
Paolo Consonni ◽  
Carlo Trombetta ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Prostate Carcinoma ◽  
Definitive Treatment

Role of Imaging and Biopsy to Assess Local Recurrence After Definitive Treatment for Prostate Carcinoma

2017 ◽  
pp. 327-342
Author(s):  
Pasquale Martino ◽  
Vincenzo Scattoni ◽  
Andrea B. Galosi ◽  
Paolo Consonni ◽  
Carlo Trombetta ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Prostate Carcinoma ◽  
Definitive Treatment

scholarly journals Radiation-Associated Angiosarcoma of the Breast and Chest Wall Treated with Thermography-Controlled, Contactless wIRA-Hyperthermia and Hypofractionated Re-Irradiation

Cancers ◽  
2021 ◽  
Vol 13 (15) ◽  
pp. 3911
Author(s):  
Markus Notter ◽  
Emanuel Stutz ◽  
Andreas R. Thomsen ◽  
Peter Vaupel
Keyword(s):  
Local Recurrence ◽  
Background Radiation ◽  
Definitive Treatment ◽  
Resection Margins ◽  
Recurrence Rates ◽  
Rate Dependent ◽  
Angiosarcoma Of The Breast ◽  
Positive Resection Margins ◽  
Locally Recurrent ◽  
Tumor Extent

Background: Radiation-associated angiosarcoma of the breast (RAASB) is a rare, challenging disease, with surgery being the accepted basic therapeutic approach. In contrast, the role of adjuvant and systemic therapies is a subject of some controversy. Local recurrence rates reported in the literature are mostly heterogeneous and are highly dependent on the extent of surgery. In cases of locally recurrent or unresectable RAASB, prognosis is very poor. Methods: We retrospectively report on 10 consecutive RAASB patients, most of them presenting with locally recurrent or unresectable RAASB, which were treated with thermography-controlled water-filtered infrared-A (wIRA) superficial hyperthermia (HT) immediately followed by re-irradiation (re-RT). Patients with RAASB were graded based on their tumor extent before onset of radiotherapy (RT). Results: We recorded a local control (LC) rate dependent on tumor extent ranging from a high LC rate of 100% (two of two patients) in the adjuvant setting with an R0 or R2 resection to a limited LC rate of 33% (one of three patients) in patients with inoperable, macroscopic tumor lesions. Conclusion: Combined HT and re-RT should be considered as an option (a) for adjuvant treatment of RAASB, especially in cases with positive resection margins and after surgery of local recurrence (LR), and (b) for definitive treatment of unresectable RAASB.

Limited efficacy of salvage radiotherapy for biopsy confirmed or clinically palpable local recurrence of prostate carcinoma after surgery

2005 ◽  
Vol 74 (2) ◽  
pp. 163-167 ◽  
Author(s):  
Richard Choo ◽  
Gerard Morton ◽  
Cyril Danjoux ◽  
Eugene Hong ◽  
Ewa Szumacher ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Prostate Carcinoma ◽  
Salvage Radiotherapy ◽  
Limited Efficacy

The role of human papillomavirus infection in prostate carcinoma

2010 ◽  
Vol 43 (1) ◽  
pp. 64-69 ◽  
Author(s):  
Arezoo Aghakhani ◽  
Rasool Hamkar ◽  
Mahmoud Parvin ◽  
Nastaran Ghavami ◽  
Mahsa Nadri ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Prostate Carcinoma ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

The Susceptibility of Healthy People to COVID-19 Infection and the Role of ACE2

2021 ◽  
Author(s):  
Mehdi Kushkestani ◽  
Mohsen Parvani ◽  
Bakhtyar Tartibian ◽  
Rasoul Eslami
Keyword(s):  
Risk Factors ◽  
Cost Effective ◽  
Normal Subjects ◽  
Definitive Treatment ◽  
Activity Levels ◽  
Cost Effective Approach ◽  
Increased Risk ◽  
Physical Activity Levels ◽  
Ace2 Gene

The COVID-19 virus has caused many deaths of people worldwide since the pandemic began. However, no definitive treatment for this infection has been discovered so far. It has been shown that comorbidities such as diabetes, hypertension and cardiovascular diseases are associated with an increased risk of SARS-COV-2 infection. Interestingly, SARS-COV-2, like SARS-COV, uses the ACE2 gene to enter the host cell. Also, changes or imbalance in ACE2.ACE can affect SARS-COV-2 susceptibility, related outcomes and mortality. Regarding the crucial role of ACE2 protein in COVID-19 infection, the effect of different factors such as age, BMI, physical activity levels, nutritional status, altitude, as well as blood group was assessed on the level of this protein. Further, to our knowledge, no study has been conducted to examine factors that increase or decrease the risk of COVID-19 and its related severity and outcome in normal subjects emphasizing the pivotal role of ACE2. Therefore, the primary purpose of this study was to investigate the involved mechanisms of ACE2 protein and other risk factors causing infection in different situations and finally, to introduce a safe, accurate, and cost-effective approach to prevent SARS-COV-2 infection and hard clinical outcomes in normal subjects.

Role of autoimmunity in organ allograft rejection: a focus on immunity to type V collagen in the pathogenesis of lung transplant rejection

2004 ◽  
Vol 286 (6) ◽  
pp. L1129-L1139 ◽  
Author(s):  
Tina L. Sumpter ◽  
David S. Wilkes
Keyword(s):  
Lung Transplantation ◽  
Lung Transplant ◽  
Transplant Rejection ◽  
Survival Rates ◽  
Definitive Treatment ◽  
Solid Organ ◽  
Type V Collagen ◽  
End Stage ◽  
Type V

Lung transplantation is the only definitive treatment modality for many forms of end-stage lung disease. However, the lung is rejected more often than any other type of solid organ allograft due to chronic rejection known as bronchiolitis obliterans (BO). Indeed, BO is the primary reason why the 5- and 7-yr survival rates are worse for the lung than for any other transplanted organ. Alloimmunity to donor antigens is established as the primary mechanism that mediates rejection responses. However, newer immunosuppressive regimens designed to abrogate alloimmune activation have not improved survival. Therefore, these data suggest that other antigens, unrelated to donor transplantation antigens, are involved in rejection. Utilizing human and rodent studies of lung transplantation, our laboratory has documented that a native collagen, type V collagen [col(V)], is a target of the rejection response. Col(V) is highly conserved; therefore, these data indicate that transplant rejection involves both alloimmune and autoimmune responses. The role of col(V) in lung transplant rejection is described in this review article. In addition, the potential role of regulatory T cells that are crucial to modulating autoimmunity and alloimmunity is also discussed.

The Role of Fluorine Substitution in Biphenyl Methylene Imidazole-Type CYP17 Inhibitors for the Treatment of Prostate Carcinoma

ChemMedChem ◽  
2010 ◽  
Vol 5 (6) ◽  
pp. 899-910 ◽  
Author(s):  
Qingzhong Hu ◽  
Matthias Negri ◽  
Sureyya Olgen ◽  
Rolf W. Hartmann
Keyword(s):  
Prostate Carcinoma ◽  
Fluorine Substitution

scholarly journals PSEUDO PAPILLARY TUMOUR OF PANCREAS

2009 ◽  
Vol 16 (04) ◽  
pp. 609-610
Author(s):  
QURATULAIN SOOMRO ◽  
Hafeez Soomro ◽  
KHAN MUHAMMAD ◽  
Sardar Khatoon ◽  
ABDUL SAMAD SHAIKH ◽  
...  
Keyword(s):  
Excisional Biopsy ◽  
Malignant Potential ◽  
Definitive Treatment ◽  
Low Grade ◽  
Young Females ◽  
Invasive Tumour ◽  
Papillary Tumour ◽  
Pancreatic Tumour ◽  
Low Malignant Potential

During 05 years period from January 2003 to December 2007,45 cases of Ca. Pancreas were reported to LINAR and only onecase of Pseudo Papillary Tumour of Pancreas is registered. It is a rare, low malignant potential pancreatic tumour. It has unknown pathogenesisand found in young females. We report a case of 24 years old female, who presented with pain in abdomen and low grade fever of 07 monthsduration. Lepratomy and excisional biopsy was done. H/P came as Pseudo Papillary Tumour of Pancreas. At presentation no any L.N. werefound enlarged. Like other malignant pancreatic tumours, this neoplasm does not metastasize. Its definitive treatment is complete surgicalremoval, no any role of chemotherapy because it doesn't metastasized, limited role of radiotherapy in local invasive tumour or in residual mass.

Metastatic prostate carcinoma to the intradural extramedullary spinal compartment

2004 ◽  
Vol 100 (4) ◽  
pp. 375-377 ◽  
Author(s):  
Stephen J. Hentschel ◽  
Ehud Mendel ◽  
Sanjay Singh ◽  
Laurence D. Rhines
Keyword(s):  
Prostate Carcinoma ◽  
Clinical Presentation ◽  
Spinal Column ◽  
Leptomeningeal Carcinomatosis ◽  
Imaging Features ◽  
Content Type ◽  
High Incidence ◽  
Intradural Extramedullary ◽  
Metastatic Prostate Carcinoma

✓ Despite the relatively high incidence of prostate carcinoma involving the spinal column, those that are associated with spinal intradural extramedullary metastases are rare. The role of surgery for metastases to this spinal compartment is limited and palliative because presentation tends to be late in the course of the disease, particularly for prostate carcinoma. It is also considered to be part of the spectrum of leptomeningeal carcinomatosis and is associated with a high incidence of brain metastases. The authors review a rare case of prostate carcinoma metastatic to the spinal intradural extramedullary space and discuss its clinical presentation, imaging features, and surgical management.

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