Predictive value of abdominal aortic calcification index for mid-term cardiovascular events in patients with acute coronary syndrome

2019 ◽  
Vol 35 (5) ◽  
pp. 620-629 ◽  
Author(s):  
Hideo Oishi ◽  
Hideki Horibe ◽  
Yuichiro Yamase ◽  
Chikara Ueyama ◽  
Yoshio Takemoto ◽  
...  
2018 ◽  
Vol 33 (12) ◽  
pp. 2253-2259 ◽  
Author(s):  
Stan Benjamens ◽  
Robert A Pol ◽  
Andor W J M Glaudemans ◽  
Ivanka Wieringa ◽  
Stefan P Berger ◽  
...  

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Zhe Wang

Abstract Background and Aims Vascular calcification is the risk factor for cardiovascular event, cardiovascular mortality and all-cause mortality in maintenance hemodialysis (MHD) patients. We investigated the effects of abdominal aortic calcification (AAC) progression on outcomes in MHD patients. Method 111 patients who were on MHD between Jun. 2014 and Oct. 2014 in the dialysis center and finished the AAC examination at baseline and two years later were included prospectively. We evaluated the progression of AAC by AAC score (AACs) at baseline and two years later. According to the change of AACs, the patients were divided into rapid AAC progression group (change of AACs>median) and non-rapid AAC progression group (change of AACs≤median). We investigated the effects of AAC progression on outcomes in MHD patients in the follow-up period. Kaplan-Meier analysis was used to compare their survival rate. Uni- and multivariable Cox proportional hazard regression models were used to determine the risk factors of all-cause mortality, cardiovascular mortality and cardiovascular events. Results The presence of AAC was 78.4% (87/111), rapid AAC progression was seen in 54 patients, and non-rapid AAC progression was seen in 57 patients. The mean follow-up duration was 27.9(27.1, 28.0) months. Kaplan-Meier analysis showed that patients in rapid AAC progression group had a higher risk of mortality as compared to patients in non-rapid AAC progression group (P=0.017). Multivariate Cox regression analysis demonstrated that high baseline AACs (HR=1.135, 95%CI∼1.001∼1.286, P=0.048), hypoproteinemia (HR=0.789, 95%CI 0.640∼0.972, P=0.026) were independent risk factors for all-cause mortality. High baseline AACs (HR=1.187, 95%CI 1.038∼1.356, P=0.012), low spKt/V (HR=0.103, 95%CI 0.013∼0.801, P=0.030) were independent risk factors for cardiovascular mortality. Low spKt/V (HR=0.018, 95%CI 0.003∼0.115, P=0.000), hypoproteinemia (HR=0.736, 95%CI 0.608∼0.890, P=0.002) were independent risk factors for cardiovascular events. Conclusion Abdominal aortic calcification progression may increase the risk of cardiovascular events and death in MHD patients. Severity of abdominal aortic calcification, adequacy of dialysis, and nutritional status are predictors of outcomes in MHD patients.


2021 ◽  
Author(s):  
Jin He ◽  
Shubei Chen ◽  
Kewen Mao ◽  
Xiaoyan Sun ◽  
Rongjian Nie

Abstract Vascular calcification (VC) and secondary hyperparathyroidism (SHPT) are important causes of high incidence of cardiovascular events in chronic kidney disease (CKD) patients. The relationship between parathyroid hormone (PTH) and VC is very complex. Different studies have inconsistent reports on the effect of PTH on VC. The present study investigated the correlation between PTH levels and abdominal aortic calcification (AAC) in incident hemodialysis patients who did not receive calcium, calcium-containing phosphorus binders, calcitriol or vitamin D analogs. Our data confirm that serum PTH levels is significantly negatively correlated with AAC within a certain concentration range in incident hemodialysis patients who not treated with calcium or vitamin D.


2013 ◽  
Vol 5 (1) ◽  
pp. 70
Author(s):  
Yannick Lepers ◽  
Huu Tri Bui ◽  
Pierre Nazeyrollas ◽  
Anne Long ◽  
Benoit Herce ◽  
...  

2010 ◽  
Vol 42 (7) ◽  
pp. 539-545 ◽  
Author(s):  
Reza Golestani ◽  
René A. Tio ◽  
Clark J. Zeebregts ◽  
Aafke Zeilstra ◽  
Rudi A. Dierckx ◽  
...  

2012 ◽  
Vol 17 (4) ◽  
pp. 448-453 ◽  
Author(s):  
Francesca Martino ◽  
Pierluigi Di Loreto ◽  
Dario Giacomini ◽  
Manish Kaushik ◽  
Maria Pia Rodighiero ◽  
...  

2018 ◽  
Vol 102 ◽  
pp. S258-S259
Author(s):  
Stan Benjamens ◽  
Robert A. Pol ◽  
Andor W. Glaudemans ◽  
Ivanka Wieringa ◽  
Stefan P. Berger ◽  
...  

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