scholarly journals Correction to: The differential diagnostic value of selected cardiovascular biomarkers in Takotsubo syndrome

2021 ◽  
Author(s):  
Albert Topf ◽  
Moritz Mirna ◽  
Vera Paar ◽  
Lukas J. Motloch ◽  
Janine Grueninger ◽  
...  
Keyword(s):  
Diagnostic Value ◽  
Takotsubo Syndrome ◽  
Cardiovascular Biomarkers

scholarly journals The differential diagnostic value of selected cardiovascular biomarkers in Takotsubo syndrome

2021 ◽  
Author(s):  
Albert Topf ◽  
Moritz Mirna ◽  
Vera Paar ◽  
Lukas J. Motloch ◽  
Janine Grueninger ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Bleeding Risk ◽  
Serum Levels ◽  
Diagnostic Value ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Takotsubo Syndrome ◽  
Ventricular Ejection Fraction ◽  
Coronary Syndrome ◽  
High Bleeding Risk

Abstract Introduction Takotsubo syndrome (TTS) is clinically indistinguishable from an acute coronary syndrome (ACS). In the absence of valid markers for differential diagnosis, coronary angiography has been indispensable. Methods In our study, we evaluated the serum levels of sST-2, GDF-15, suPAR and H-FABP in 92 patients with the suspicion of TTS (51 TTS and 41 ACS patients) and 40 gender matched controls (no coronary artery disease or signs of heart failure) at baseline. Results H-FABP was significantly higher in ACS patients compared to TTS patients. Even in in propensity score matching for left ventricular ejection fraction, sex and cardiovascular risk factors, differences in the plasma levels of H-FABP in the matched cohort of TTS vs ACS remained statistically significant. Whereas, sST-2 was significantly elevated in TTS patients. H-FABP was superior for prediction of an ACS with even higher accuracy than hs troponin in differential diagnosis (AUC 0.797, p ≤ 0.0001); the optimal cut off for discrimination towards a TTS was calculated as 2.93 ng/ml (sensitivity 70.0%, specificity 82.4%, PPV 75.7%, NPV 77.4%). sST-2 seemed most appropriate for identification of a TTS (AUC 0.653, p = 0.012). The optimal cut off for differential diagnosis was 11018.06 pg/ml (sensitivity 82.0%, specificity 51.2%, PPV 69.4%, NPV 71.9 %). Conclusion H-FABP and sST-2 are the most promising markers with better accuracy than preexisting biomarkers in differential diagnosis in our study and therefore, could be crucial for the guidance of treatment in patients with high bleeding risk, advanced renal failure or multimorbidity. Graphical abstract

Diagnostic Value of Electron Microscopy in Soft Tissue Tumors

1970 ◽  
Vol 28 ◽  
pp. 220-221
Author(s):  
Gerald Fine ◽  
Azorides R. Morales
Keyword(s):  
Cardiac Myxoma ◽  
Osteogenic Sarcoma ◽  
Diagnostic Value ◽  
Soft Tissue Tumors ◽  
Amelanotic Melanoma ◽  
Growth Patterns ◽  
Light Microscopic Level ◽  
Mesenchymal Tumors ◽  
Good Agreement

For years the separation of carcinoma and sarcoma and the subclassification of sarcomas has been based on the appearance of the tumor cells and their microscopic growth pattern and information derived from certain histochemical and special stains. Although this method of study has produced good agreement among pathologists in the separation of carcinoma from sarcoma, it has given less uniform results in the subclassification of sarcomas. There remain examples of neoplasms of different histogenesis, the classification of which is questionable because of similar cytologic and growth patterns at the light microscopic level; i.e. amelanotic melanoma versus carcinoma and occasionally sarcoma, sarcomas with an epithelial pattern of growth simulating carcinoma, histologically similar mesenchymal tumors of different histogenesis (histiocytoma versus rhabdomyosarcoma, lytic osteogenic sarcoma versus rhabdomyosarcoma), and myxomatous mesenchymal tumors of diverse histogenesis (myxoid rhabdo and liposarcomas, cardiac myxoma, myxoid neurofibroma, etc.)

Diagnostic Value of Selective Interference with Certain Excretory Processes of the Liver

1957 ◽  
Vol 33 (2) ◽  
pp. 163-171 ◽  
Author(s):  
Perry J. Culver ◽  
William V. McDermott ◽  
Chester M. Jones
Keyword(s):  
Diagnostic Value ◽  
Selective Interference

Diagnostic Value of a New Serum Lipase Method

1965 ◽  
Vol 48 (1) ◽  
pp. 12-17 ◽  
Author(s):  
Howard E. Ticktin ◽  
Nelson P. Trujillo ◽  
Phyllis F. Evans ◽  
Joseph H. Roe
Keyword(s):  
Diagnostic Value ◽  
Serum Lipase

245 NT-proBNP diagnostic value for diagnosis of isolated diastolic LV dysfunction in ischemic heart disease

2006 ◽  
Vol 5 (1) ◽  
pp. 51-51
Author(s):  
K WITA ◽  
A FILIPECKI ◽  
Z TABOR ◽  
W WROBEL ◽  
M NOWAK ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Diagnostic Value ◽  
Ischemic Heart ◽  
Lv Dysfunction
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