Self-assembly of poly(ethylene glycol-b-phenyl oxazoline) diblock copolymers in aqueous media and their interactions with proteins

2017 ◽  
Vol 295 (8) ◽  
pp. 1359-1369 ◽  
Author(s):  
Eleni Vlassi ◽  
Aristeidis Papagiannopoulos ◽  
Stergios Pispas
2013 ◽  
Vol 662 ◽  
pp. 136-139
Author(s):  
Ge Yang ◽  
Ke Shuai Lu ◽  
Xue Yan Su

The paper describes the preparation and characterization of novel biodegradable nanoparticles based on self-assembly of poly-gamma-glutamic acid (γ-PGA) and poly(ethylene glycol) (PEG). The nanosystems were stable in aqueous media at low pH conditions. Solubility of the systems was determined by turbidity measurements. The particle size and the size distribution of the polyelectrolyte complexes were identified by dynamic lightscattering and transmission electron microscopy.It was found that the size and size distribution of the nanosystems depends on the concentrations of γ-PGA and PEG solutions and their ratio as well as on the pH of the mixture and the order of addition. The diameter of individual particles was in the range of 30–270 nm. measured by TEM, and the average hydrodynamic diameters were between 130 and 300 nm. These biodegradable, self-assembling stable nanocomplexes might be useful for several biomedical applications.


2020 ◽  
Vol 11 (23) ◽  
pp. 3922-3930
Author(s):  
Paul Galanopoulo ◽  
Pierre-Yves Dugas ◽  
Muriel Lansalot ◽  
Franck D'Agosto

The polymerization-induced self-assembly (PISA) of amphiphilic diblock copolymers of poly(ethylene glycol)-b-poly(vinyl acetate) in water was achieved through macromolecular design via interchange of xanthate (MADIX) polymerization in emulsion.


RSC Advances ◽  
2016 ◽  
Vol 6 (29) ◽  
pp. 24142-24153
Author(s):  
Andreea S. Voda ◽  
Kevin Magniez ◽  
Nisa V. Salim ◽  
Cynthia Wong ◽  
Qipeng Guo

We report for the first time the use of Nα-Boc-l-tryptophan for the synthesis of amphiphilic BAB triblock copolymers for potential drug delivery applications.


2010 ◽  
Vol 36 (4) ◽  
pp. 456-469 ◽  
Author(s):  
Roudayna Diab ◽  
Misara Hamoudeh ◽  
Olivier Boyron ◽  
Abdelhamid Elaissari ◽  
Hatem Fessi

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