Extraskeletal myxoid chondrosarcoma: a review of 23 patients treated at a single referral center with long-term follow-up

2012 ◽  
Vol 132 (10) ◽  
pp. 1379-1386 ◽  
Author(s):  
Koichi Ogura ◽  
Tomohiro Fujiwara ◽  
Yasuo Beppu ◽  
Hirokazu Chuman ◽  
Akihiko Yoshida ◽  
...  
Keyword(s):  
Extraskeletal Myxoid Chondrosarcoma ◽  
Referral Center ◽  
Myxoid Chondrosarcoma ◽  
Long Term Follow Up

Mo1317 Type III Sphincter of Oddi Dysfunction (SOD): Long Term Follow up At a Tertiary Referral Center

2012 ◽  
Vol 75 (4) ◽  
pp. AB387
Author(s):  
Marc F. Catalano ◽  
Mahmoud Lajin ◽  
Naser M. Khan ◽  
Nalini M. Guda ◽  
Joseph E. Geenen
Keyword(s):  
Sphincter Of Oddi ◽  
Sphincter Of Oddi Dysfunction ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Type Iii ◽  
Long Term Follow Up ◽  
Oddi Dysfunction

Long-term follow-up of patients with infective endocarditis in a tertiary referral center

2021 ◽  
Author(s):  
Jeroen Tahon ◽  
Pieter-Jan Geselle ◽  
Bert Vandenberk ◽  
Evelyn E. Hill ◽  
Willy E. Peetermans ◽  
...  
Keyword(s):  
Infective Endocarditis ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Long Term Follow Up

scholarly journals Locally recurrent extraskeletal myxoid chondrosarcoma of the shoulder: a case of complete neoadjuvant radiotherapy response

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Luca Improta ◽  
Sergio Valeri ◽  
Rossana Alloni ◽  
Chiara Pagnoni ◽  
Francesco Mallozzi Santa Maria ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Local Recurrence ◽  
Distant Metastasis ◽  
Surgical Excision ◽  
Lower Limbs ◽  
Extraskeletal Myxoid Chondrosarcoma ◽  
Combined Treatments ◽  
Referral Center ◽  
Myxoid Chondrosarcoma

Abstract Background Extraskeletal myxoid chondrosarcoma (EMC) is a rare soft tissue tumor that typically affects the lower limbs of men between the ages of 50 and 60. EMC of the shoulder is rare with a high risk of local recurrence and distant metastasis. A planned surgical excision in sarcoma referral centers (SRCs) is mandatory to obtain the best outcome. The role of chemotherapy (CHT) and Radiotherapy (RT) on soft tissue chondrosarcoma is still controversial. Case presentation A 47-year-old man presented to our referral center with a history of EMC in the right shoulder excised with microscopic positive surgical margins in a non-referral center. Staging imaging exams did not reveal distant metastasis or residual disease, but during follow-up a local recurrence was detected. After a multidisciplinary discussion, preoperative radiotherapy was administered with a total dose of 50 Gy, and then the patient underwent wide surgical excision. Histological examination was negative for viable tumor cells. No relapse occurred in a 24-months post-operative follow up. Conclusions The case here described suggests the importance of patient’s management in SRCs. A planned combined treatments with both surgery and RT seems to be the best choice to improve local control. RT seems to be promising within this specific histotype. Further studies are needed to confirm if the observed efficacy of combined treatments reflects in a consistent survival benefit for EMC patients.

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

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