SNP rs12794714 of CYP2R1 is associated with serum vitamin D levels and recurrent spontaneous abortion (RSA): a case–control study

2021 ◽  
Author(s):  
Ding-Yuan Liu ◽  
Ren-Yan Li ◽  
Li-Juan Fu ◽  
Enoch Appiah Adu-Gyamfi ◽  
Yin Yang ◽  
...  
Keyword(s):  
Vitamin D ◽  
Spontaneous Abortion ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Recurrent Spontaneous Abortion ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Control Study

scholarly journals A case control study of serum vitamin D levels in alopecia areata

2020 ◽  
Vol 8 (10) ◽  
pp. 3550
Author(s):  
Bobbili Tarun Kesava Naidu ◽  
Kavya Baddireddy
Keyword(s):  
Vitamin D ◽  
Alopecia Areata ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Autoimmune Disorder ◽  
Case Control ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Severity Of The Disease ◽  
Control Study

Background: Alopecia areata is an autoimmune disorder of anagen hair follicle leading to distressing and relapsing non-scarring hair loss. Vitamin D is an immunomodulator and plays a role in regulating normal hair cycle. Recent evidence suggests inconsistent association between vitamin D deficiency and alopecia areata.Methods: This case control study included 70 newly diagnosed cases of alopecia areata and 70 healthy controls. Competitive chemiluminescence immunoassay was used to determine and compare the serum vitamin D (25‑hydroxyvitamin D) levels between these groups. Also, the serum vitamin D levels correlation with severity of the disease was studied. ANOVA test and student t test were used for the statistical analysis.Results: Serum Vitamin D levels were significantly decreased in alopecia areata patients than in controls (p<0.05). There was no stastically significant relationship between serum 25-OH Vitamin D levels and severity of the disease (p=0.06).Conclusions: Prevalence of serum 25 (OH) deficiency was significantly higher in alopecia areata group. However no significant relation was found with disease severity.

scholarly journals The determinants of serum vitamin D levels in participants in a melanoma case–control study living in a temperate climate

2011 ◽  
Vol 22 (10) ◽  
pp. 1471-1482 ◽  
Author(s):  
John R. Davies ◽  
Yu-Mei Chang ◽  
Helen Snowden ◽  
May Chan ◽  
Susan Leake ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Temperate Climate ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Control Study ◽  
Melanoma Case

scholarly journals Prediagnostic Serum Vitamin D Levels and the Risk of Crohn’s Disease and Ulcerative Colitis in European Populations: A Nested Case-Control Study

2018 ◽  
Vol 24 (3) ◽  
pp. 633-640 ◽  
Author(s):  
Jorrit L Opstelten ◽  
Simon S M Chan ◽  
Andrew R Hart ◽  
Fiona D M van Schaik ◽  
Peter D Siersema ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Nested Case Control ◽  
Control Study ◽  
European Populations

Prediagnostic Serum Vitamin D Levels and Risk of Inflammatory Bowel Disease: A Pan-European, Nested Case-control Study

2017 ◽  
Vol 152 (5) ◽  
pp. S59 ◽  
Author(s):  
Jorrit Opstelten ◽  
Simon Chan ◽  
Andrew Hart ◽  
Fiona van Schaik ◽  
Peter D. Siersema ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Vitamin D ◽  
Case Control Study ◽  
Serum Vitamin ◽  
Case Control ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Inflammatory Bowel ◽  
Nested Case Control ◽  
Control Study

scholarly journals Assessment of Serum Vitamin D Levels in Patients with Vitiligo in Jordan: A Case-Control Study

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Diala M. Alshiyab ◽  
Firas A. Al-qarqaz ◽  
Leen H. Heis ◽  
Jihan M. Muhaidat ◽  
Wlla S. Eddin ◽  
...  
Keyword(s):  
Vitamin D ◽  
Case Control Study ◽  
Skin Diseases ◽  
Serum Vitamin ◽  
Case Control ◽  
Vitamin D Receptors ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
Control Study

Background. Low vitamin D serum levels have been associated with many autoimmune disorders and several other skin diseases. Vitiligo is an autoimmune disease characterized by destruction of melanocytes by immune mechanisms. Melanocytes express vitamin D receptors, and their function can be affected by vitamin D status. Objectives. The main objective of this study is to compare vitamin D levels in patients with vitiligo vs normal population and whether vitamin D deficiency is associated with vitiligo. Methods. A case-control study was conducted. 100 vitiligo patients and 100 as controls were included in this study. Serum vitamin D level was measured for both vitiligo patients and controls, results were compared, and statistical analysis was done to compare the results. Results. The median age of vitiligo cases was 23 years (ranges, 2–80). 58% of vitiligo patients were females. The median vitamin D level was not significantly different between the two groups (vitiligo = 14.1 (IQR 9.9–20.4) vs control = 16.5 (IQR 10.3–25.3) (P=0.28)). Most vitiligo cases and controls were found to have low levels of vitamin D (either insufficient 20–30 ng/mL or low <20 ng/mL). Conclusions. There was no significant difference in vitamin D levels in vitiligo patients compared to controls. However, vitamin D levels were generally low in both groups.

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