Developmental validation of the STRscan-17LC kit: a 6 Dye STR kit enhanced stability and ability to detect degraded samples

2021 ◽  
Vol 135 (2) ◽  
pp. 431-440
Author(s):  
Bowei Jiang ◽  
Wei He ◽  
Chuan Jin ◽  
Ying Liu ◽  
Dan Wen ◽  
...  
Author(s):  
Maryam Aisyah Abdullah ◽  
Siti Munirah Mohd Faudzi ◽  
Nadiah Mad Nasir

Abstract:: Medicinal chemists have continuously shown interest in new curcuminoid derivatives, the diarylpentadienones, owing to their enhanced stability feature and easy preparation using a one-pot synthesis. Thus far, methods such as Claisen-Schmidt condensation and Julia-Kocienski olefination have been utilised for the synthesis of these compounds. Diarylpentadienones possess a high potential as a chemical source for designing and developing new and effective drugs for the treatment of diseases, including inflammation, cancer, and malaria. In brief, this review article focuses on the broad pharmacological applications and the summary of the structure-activity relationship of molecules which can be employed to further explore the structure of diarylpentadienone. The current methodological developments towards the synthesis of diarylpentadienones are also discussed.


2018 ◽  
Vol 18 (10) ◽  
pp. 857-880 ◽  
Author(s):  
Salma E. Ahmed ◽  
Nahid Awad ◽  
Vinod Paul ◽  
Hesham G. Moussa ◽  
Ghaleb A. Husseini

Conventional chemotherapeutics lack the specificity and controllability, thus may poison healthy cells while attempting to kill cancerous ones. Newly developed nano-drug delivery systems have shown promise in delivering anti-tumor agents with enhanced stability, durability and overall performance; especially when used along with targeting and triggering techniques. This work traces back the history of chemotherapy, addressing the main challenges that have encouraged the medical researchers to seek a sanctuary in nanotechnological-based drug delivery systems that are grafted with appropriate targeting techniques and drug release mechanisms. A special focus will be directed to acoustically triggered liposomes encapsulating doxorubicin.


2015 ◽  
Vol 294 ◽  
pp. 248-253 ◽  
Author(s):  
Agnese Birrozzi ◽  
Fabio Maroni ◽  
Rinaldo Raccichini ◽  
Roberto Tossici ◽  
Roberto Marassi ◽  
...  

2021 ◽  
pp. 100122
Author(s):  
Alexandra H. Teodor ◽  
Lucas B. Thal ◽  
Shinduri Vijayakumar ◽  
Madison Chan ◽  
Gabriela Little ◽  
...  

2021 ◽  
Author(s):  
XINGYUN Li ◽  
Bin Han ◽  
Yaojie Xu ◽  
Xiao Liu ◽  
Chunhui Zhao ◽  
...  

As an advanced two-dimensional (2D) material with unique properties, black phosphorus (BP) has attracted great attention in a variety of fields. One of the main obstacles for practical application of...


2011 ◽  
Vol 56 (4) ◽  
pp. 853-865 ◽  
Author(s):  
Kevin W. P. Miller ◽  
Jennifer Old ◽  
Brian R. Fischer ◽  
Brett Schweers ◽  
Simona Stipinaite ◽  
...  

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