Gene expression profiling of giant cell tumor of bone reveals downregulation of extracellular matrix components decorin and lumican associated with lung metastasis

2014 ◽  
Vol 465 (6) ◽  
pp. 703-713 ◽  
Author(s):  
M. Lieveld ◽  
E. Bodson ◽  
G. De Boeck ◽  
B. Nouman ◽  
A. M. Cleton-Jansen ◽  
...  
Keyword(s):  
Gene Expression ◽  
Extracellular Matrix ◽  
Gene Expression Profiling ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Lung Metastasis ◽  
Expression Profiling ◽  
Cell Tumor ◽  
Extracellular Matrix Components ◽  
Matrix Components

scholarly journals Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the bone

2008 ◽  
Vol 21 (5) ◽  
pp. 531-539 ◽  
Author(s):  
Cheng-Han Lee ◽  
Inigo Espinosa ◽  
Kristin C Jensen ◽  
Subbaya Subramanian ◽  
Shirley X Zhu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Gene Expression Profiling ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Expression Profiling ◽  
Diagnostic Marker ◽  
Cell Tumor

scholarly journals Gene Expression Profiling of Extracellular Matrix as an Effector of Human Hepatocyte Phenotype in Primary Cell Culture

2007 ◽  
Vol 97 (2) ◽  
pp. 384-397 ◽  
Author(s):  
J. L. Page ◽  
M. C. Johnson ◽  
K. M. Olsavsky ◽  
S. C. Strom ◽  
H. Zarbl ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cell Culture ◽  
Extracellular Matrix ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Primary Cell Culture ◽  
Human Hepatocyte ◽  
Primary Cell

DNA methylation and gene expression profiling reveal MFAP5 as a regulatory driver of extracellular matrix remodeling in varicose vein disease

Epigenomics ◽  
2018 ◽  
Vol 10 (8) ◽  
pp. 1103-1119 ◽  
Author(s):  
Mariya A Smetanina ◽  
Alexander E Kel ◽  
Ksenia S Sevost'ianova ◽  
Igor V Maiborodin ◽  
Andrey I Shevela ◽  
...  
Keyword(s):  
Gene Expression ◽  
Dna Methylation ◽  
Extracellular Matrix ◽  
Gene Expression Profiling ◽  
Varicose Vein ◽  
Expression Profiling ◽  
Extracellular Matrix Remodeling ◽  
Matrix Remodeling ◽  
Vein Disease

Erratum: Expression and Localization of Extracellular Matrix Metalloproteinase Inducer in Giant Cell Tumor of Bone.

2012 ◽  
Vol 113 (11) ◽  
pp. 3599-3599
Author(s):  
Andrew I.C. Si ◽  
Lin Huang ◽  
Jiake Xu ◽  
Shekhar–M Kumta ◽  
David Wood ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Matrix Metalloproteinase ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Cell Tumor ◽  
Extracellular Matrix Metalloproteinase Inducer

Surveillance for lung metastasis from giant cell tumor of bone

2017 ◽  
Vol 116 (7) ◽  
pp. 907-913 ◽  
Author(s):  
Mamer Rosario ◽  
Han-Soo Kim ◽  
Ji Yeon Yun ◽  
Ilkyu Han
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Lung Metastasis ◽  
Cell Tumor

Endometrial gene expression of acute phase extracellular matrix components following estrogen disruption of pregnancy in pigs

2010 ◽  
Vol 122 (3-4) ◽  
pp. 215-221 ◽  
Author(s):  
Morgan D. Ashworth ◽  
Jason W. Ross ◽  
Daniel Stein ◽  
Frank White ◽  
Rodney D. Geisert
Keyword(s):  
Gene Expression ◽  
Extracellular Matrix ◽  
Acute Phase ◽  
Extracellular Matrix Components ◽  
Matrix Components

scholarly journals Cancer Cell-derived Secretory Factors in Breast Cancer-associated Lung Metastasis: Their Mechanism and Future Prospects

2020 ◽  
Vol 20 (3) ◽  
pp. 168-186 ◽  
Author(s):  
Tabinda Urooj ◽  
Bushra Wasim ◽  
Shamim Mushtaq ◽  
Syed Nudrat Nawaid Shah ◽  
Muzna Shah
Keyword(s):  
Breast Cancer ◽  
Extracellular Matrix ◽  
Cancer Cell ◽  
Lung Metastasis ◽  
Primary Site ◽  
Ecm Remodeling ◽  
Metastatic Cells ◽  
Extracellular Matrix Components ◽  
Matrix Components

: In Breast cancer, Lung is the second most common site of metastasis after the bone. Various factors are responsible for Lung metastasis occurring secondary to Breast cancer. Cancer cellderived secretory factors are commonly known as ‘Cancer Secretomes’. They exhibit a prompt role in the mechanism of Breast cancer lung metastasis. They are also major constituents of hostassociated tumor microenvironment. Through cross-talk between cancer cells and the extracellular matrix components, cancer cell-derived extracellular matrix components (CCECs) such as hyaluronan, collagens, laminin and fibronectin cause ECM remodeling at the primary site (breast) of cancer. However, at the secondary site (lung), tenascin C, periostin and lysyl oxidase, along with pro-metastatic molecules Coco and GALNT14, contribute to the formation of pre-metastatic niche (PMN) by promoting ECM remodeling and lung metastatic cells colonization. Cancer cell-derived secretory factors by inducing cancer cell proliferation at the primary site, their invasion through the tissues and vessels and early colonization of metastatic cells in the PMN, potentiate the mechanism of Lung metastasis in Breast cancer. : On the basis of biochemical structure, these secretory factors are broadly classified into proteins and non-proteins. This is the first review that has highlighted the role of cancer cell-derived secretory factors in Breast cancer Lung metastasis (BCLM). It also enumerates various researches that have been conducted to date in breast cancer cell lines and animal models that depict the prompt role of various types of cancer cell-derived secretory factors involved in the process of Breast cancer lung metastasis. In the future, by therapeutically targeting these cancer driven molecules, this specific type of organ-tropic metastasis in breast cancer can be successfully treated.

scholarly journals Clinical characteristics and risk factors analysis of lung metastasis from benign giant cell tumor of bone

2017 ◽  
Vol 7 ◽  
pp. 23-28 ◽  
Author(s):  
Yongkun Yang ◽  
Zhen Huang ◽  
Xiaohui Niu ◽  
Hairong Xu ◽  
Yuan Li ◽  
...  
Keyword(s):  
Risk Factors ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Lung Metastasis ◽  
Clinical Characteristics ◽  
Cell Tumor ◽  
Factors Analysis
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