The advanced development of Cx43 and GAP-43 mediated intercellular networking in IDH1 wildtype diffuse and anaplastic gliomas with lower mitotic rate

2021 ◽  
Author(s):  
Aleksandrs Krigers ◽  
Patrizia Moser ◽  
Helga Fritsch ◽  
Matthias Demetz ◽  
Konstantin Brawanski ◽  
...  
Keyword(s):  
Mitotic Rate ◽  
Anaplastic Gliomas ◽  
Advanced Development

THE PARATHYROIDS IN CORTICOSTEROID-TREATED PREGNANT RATS AND THEIR OFFSPRING

1966 ◽  
Vol 53 (4) ◽  
pp. 547-552 ◽  
Author(s):  
C. Göran Hansson ◽  
Lennart Angervall
Keyword(s):  
Mitotic Rate ◽  
Pregnant Rats

ABSTRACT Geometrically increasing doses of cortisone (0.5, 1.5 and 4.5 mg twice daily) were injected into pregnant rats, and the volume, nuclear diameters and mitotic rate of the maternal parathyroids as well as the parathyroid volume and mitotic rate in the foetuses were determined. The nuclear diameters were if anything smaller and the mitotic rate tended to decrease in the cortisone treated groups. There were no significant differences between the parathyroid volumes of the foetuses in the control and cortisone-treated groups. Thus, it seems that the development of the rat foetal parathyroids and the morphology of the maternal parathyroids are little affected if at all, by cortisone.

A Methodology of integrated assessment of the investment attractiveness of the priority social and economic development areas

2020 ◽  
Vol 18 (4) ◽  
pp. 780-806 ◽  
Author(s):  
V.A. Yakimova ◽  
S.V. Khmura
Keyword(s):  
Integrated Assessment ◽  
Investment Risk ◽  
Methodological Issues ◽  
Investment Environment ◽  
Social And Economic Development ◽  
Analysis And Synthesis ◽  
Current Assessment ◽  
Development Area ◽  
Internal And External Factors ◽  
Advanced Development

Subject. This article deals with the theoretical and methodological issues of assessing the investment attractiveness of the advanced development areas. Objectives. The article aims to clarify the economic essence of the category Investment Attractiveness of Advanced Development Areas and related categories, and improve the methodological support to assess the investment attractiveness taking into account the characteristics of these areas. Methods. For the study, we used the methods of analysis and synthesis, generalization, analogy, classification, grouping, and systematization. Results. The article presents a methodology for assessing the investment attractiveness of the advanced development areas, taking into account indicators classified under three groups, namely investment potential, investment environment, and investment risk. It also offers recommendations to determine the type of investment attractiveness. Conclusions. Investment attractiveness, as a complex characteristic of the advanced development area, gets formed in the context of the influence of internal and external factors that are quantifiable and qualitatively assessed. To meet the needs of investors, a methodology that includes current assessment and forecasts is needed, indicating the areas of possible investment risk.

Assessment of sensitivity of the efficiency of regional tax spending towards investment attractiveness of the types of economic activity carried out by the residents of advanced development territory

2020 ◽  
pp. 98-110
Author(s):  
Evgeniya Mikhailovna Popova ◽  
Guzel Mukhtarovna Guseinova ◽  
Sergei Borisovich Milov
Keyword(s):  
Economic Activity ◽  
Socioeconomic Development ◽  
Federal District ◽  
Tax Incentives ◽  
Capital Investments ◽  
The Subject ◽  
Investment Process ◽  
The Impact ◽  
Advanced Development

The deficit of subnational budgets and deceleration capital investments in multiple Russian regions increase the relevance of research aimed at improvement of tax incentivizing practice of the regional investment process. The studies focused on determination of the impact of socioeconomic and institutional factors upon the efficiency of investment tax expenses obtained wide circulation within the foreign scientific literature. The subject of this article is the assessment of sensitivity of the efficiency of regional tax expanses towards investment attractiveness of the types of economic activity carried out by the residents of territories of advanced socioeconomic development, created in the subjects of Far Easter Federal District. The scientific novelty and practical values of this research consists in substantiation of the reasonableness of assessment of investment attractiveness of the types of economic activity that are stimulated by tax incentives. Methodology for assessing investment attractiveness is proposed and tested. The conclusion is made that in case of low investment attractiveness of the type of economic activity, which was planned to support by tax incentives, it is required to conduct and additional analysis to avoid unjustified tax expanses.

Digital economy: conceptual and strategic aspects of development

2020 ◽  
pp. 40-52
Author(s):  
D. Volkov
Keyword(s):  
Public Administration ◽  
Digital Technologies ◽  
Digital Economy ◽  
The State ◽  
Long Wave ◽  
End To End ◽  
Advanced Development ◽  
Digital Sphere

The article proves the need to "return" the state to the economy in order to implement digital mobilization and form a new mechanism of public administration, including the article analyzes the key conditions for Russia’s transition to the path of "advanced development", reveals not only the content of the levels of the digital sphere, but also its end-to-end digital technologies, all the challenges and threats generated by the development of the digital economy, examines the need and possibility of Russia’s movement to the sixth technological order, provides an algorithm for the transition to the phase of a new long wave (the big or Kondratiev cycle).

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