Eisosomes and plasma membrane organization

2012 ◽  
Vol 287 (8) ◽  
pp. 607-620 ◽  
Author(s):  
Agustina Olivera-Couto ◽  
Pablo S. Aguilar
Keyword(s):  
Plasma Membrane ◽  
Membrane Organization

scholarly journals Mammalian Fat and Dachsous cadherins regulate apical membrane organization in the embryonic cerebral cortex

2009 ◽  
Vol 185 (6) ◽  
pp. 959-967 ◽  
Author(s):  
Takashi Ishiuchi ◽  
Kazuyo Misaki ◽  
Shigenobu Yonemura ◽  
Masatoshi Takeichi ◽  
Takuji Tanoue
Keyword(s):  
Cerebral Cortex ◽  
Plasma Membrane ◽  
Progenitor Cells ◽  
Neural Progenitor Cells ◽  
Apical Membrane ◽  
Neural Progenitor ◽  
Apical Plasma Membrane ◽  
Cell Contact ◽  
Membrane Organization ◽  
A Cell

Compartmentalization of the plasma membrane in a cell is fundamental for its proper functions. In this study, we present evidence that mammalian Fat4 and Dachsous1 cadherins regulate the apical plasma membrane organization in the embryonic cerebral cortex. In neural progenitor cells of the cortex, Fat4 and Dachsous1 were concentrated together in a cell–cell contact area positioned more apically than the adherens junction (AJ). These molecules interacted in a heterophilic fashion, affecting their respective protein levels. We further found that Fat4 associated and colocalized with the Pals1 complex. Ultrastructurally, the apical junctions of the progenitor cells comprised the AJ and a stretch of plasma membrane apposition extending apically from the AJ, which positionally corresponded to the Fat4–Dachsous1-positive zone. Depletion of Fat4 or Pals1 abolished this membrane apposition. These results highlight the importance of the Fat4–Dachsous1–Pals1 complex in organizing the apical membrane architecture of neural progenitor cells.

scholarly journals Alteration of Plasma Membrane Organization by an Anticancer Lysophosphatidylcholine Analogue Induces Intracellular Acidification and Internalization of Plasma Membrane Transporters in Yeast

2013 ◽  
Vol 288 (12) ◽  
pp. 8419-8432 ◽  
Author(s):  
Ola Czyz ◽  
Teshager Bitew ◽  
Alvaro Cuesta-Marbán ◽  
Christopher R. McMaster ◽  
Faustino Mollinedo ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Membrane Transporters ◽  
Membrane Organization ◽  
Intracellular Acidification

scholarly journals Plasma membrane organization and dynamics is probe and cell line dependent

2017 ◽  
Vol 1859 (9) ◽  
pp. 1483-1492 ◽  
Author(s):  
Shuangru Huang ◽  
Shi Ying Lim ◽  
Anjali Gupta ◽  
Nirmalya Bag ◽  
Thorsten Wohland
Keyword(s):  
Plasma Membrane ◽  
Cell Line ◽  
Membrane Organization

scholarly journals Antral follicle development influences plasma membrane organization but not cortical granule distribution in mouse oocytes

1998 ◽  
Vol 13 (10) ◽  
pp. 2842-2847 ◽  
Author(s):  
S. Cecconi ◽  
R. Focarelli ◽  
G. Rossi ◽  
R. Talevi ◽  
R. Colonna
Keyword(s):  
Plasma Membrane ◽  
Antral Follicle ◽  
Cortical Granule ◽  
Follicle Development ◽  
Membrane Organization ◽  
Mouse Oocytes

Lipid–Protein Interactions in Plasma Membrane Organization and Function

2022 ◽  
Vol 51 (1) ◽  
Author(s):  
Taras Sych ◽  
Kandice R. Levental ◽  
Erdinc Sezgin
Keyword(s):  
Plasma Membrane ◽  
Protein Interactions ◽  
Collective Behavior ◽  
Protein Function ◽  
Lipid Binding ◽  
Publication Date ◽  
Membrane Organization ◽  
Lipid Protein Interactions ◽  
And Function ◽  
Specific Lipid

Lipid–protein interactions in cells are involved in various biological processes, including metabolism, trafficking, signaling, host–pathogen interactions, and transmembrane transport. At the plasma membrane, lipid–protein interactions play major roles in membrane organization and function. Several membrane proteins have motifs for specific lipid binding, which modulate protein conformation and consequent function. In addition to such specific lipid–protein interactions, protein function can be regulated by the dynamic, collective behavior of lipids in membranes. Emerging analytical, biochemical, and computational technologies allow us to study the influence of specific lipid–protein interactions, as well as the collective behavior of membranes on protein function. In this article, we review the recent literature on lipid–protein interactions with a specific focus on the current state-of-the-art technologies that enable novel insights into these interactions. Expected final online publication date for the Annual Review of Biophysics, Volume 51 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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