Gastrointestinal stromal tumors (GIST) and laparoscopic resection

Background The aim of this study was to conduct a meta-analysis comparing the safety and feasibility of laparoscopic versus open resection for gastric gastrointestinal stromal tumors (GISTs) larger than 5 cm. Method We searched the Cochrane Library, PubMed, and Embase for relevant articles. Randomized and nonrandomized clinical trials were identified and included in this study. Searching for related articles on large GIST (>5 cm) for laparoscopic resection (laparoscopic group [LAPG]) and open resection (open group [OG]), RevMan 5.3 was used for data analysis, comparing 2 groups of operation time, intraoperative blood loss, complications, length of hospital stay, recurrence rate, disease-free survival, and overall survival. Results Seven studies including 440 patients were identified for the meta-analysis. Meta-analysis revealed that LAPG had less bleeding, shorter postoperative hospital stay, and a better 5-year disease-free survival. There was no significant difference between LAPG and OG in operation time, postoperative complications, recurrence rate, and overall survival. Conclusion Laparoscopic resection of large (>5 cm) GIST is safe and feasible and has the advantages of less intraoperative blood loss and fast postoperative recovery, with a good outcome in the recent oncology.

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Laparoscopic Resection of Gastrointestinal Stromal Tumors

Minimally Invasive Cancer Management ◽

10.1007/978-1-4419-1238-1_9 ◽

2009 ◽

pp. 99-111

Author(s):

Ajita S. Prabhu ◽

B. Todd Heniford

Keyword(s):

Gastrointestinal Stromal Tumors ◽

Laparoscopic Resection ◽

Stromal Tumors

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Surgical Management of Benign Gastric Tumors: A Review

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2021/v33i60a34502 ◽

2021 ◽

pp. 420-426

Author(s):

Hashem Bark Awadh Abood ◽

Amani Nasser D. Albalawi ◽

Haifa Obedullah AlEnazi ◽

Mousa Mutlaq Almuhanna ◽

Norah Othman Busaad ◽

...

Keyword(s):

Computed Tomography ◽

Gastrointestinal Stromal Tumors ◽

Laparoscopic Resection ◽

Benign Tumors ◽

Stromal Tumors ◽

Gastric Tumors ◽

Laparoscopic Excision ◽

Long Time ◽

The Difference ◽

Stomach Epithelium

Benign stomach and duodenal tumors are uncommon. Any component of the stomach epithelium, whether glandular, endocrine, or mesenchymal, can develop benign neoplastic tumors. The majority of people with benign stomach and duodenal tumors are asymptomatic for a long time. When symptoms do appear, they are determined by the tumor's size, location, and comorbidities. Endoscopy, computed tomography, and especially endoscopic ultrasonography results are used diagnose. Clinically, it's difficult to tell the difference between benign and malignant stomach tumors. Even benign tumors can undergo malignant transformation, severe obstructive problems, and bleeding. As a result, aggressive surgical resection of the tumors should be undertaken. Laparoscopic resection has become the first option of many surgeons since the development of minimally invasive surgery. According to previous literature, laparoscopic excision of GIST is safe and effective. In this review we’ll be looking at benign gastric tumors, gastrointestinal stromal tumors (GISTs) and their diagnosis.

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A Systematic Review and Meta-Analysis of Open vs. Laparoscopic Resection of Gastric Gastrointestinal Stromal Tumors

Journal of Clinical Medicine Research ◽

10.14740/jocmr1547w ◽

2015 ◽

Vol 7 (5) ◽

pp. 289-296 ◽

Cited By ~ 18

Author(s):

Jean-Sebastien Pelletier ◽

Richdeep S. Gill ◽

Sayf Gazala ◽

Shahzeer Karmali

Keyword(s):

Systematic Review ◽

Gastrointestinal Stromal Tumors ◽

Laparoscopic Resection ◽

Meta Analysis ◽

Stromal Tumors

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Various fashions of laparoscopic resection for gastrointestinal stromal tumors in esophagogastric junction.

Journal of Clinical Oncology ◽

10.1200/jco.2017.35.15_suppl.e22512 ◽

2017 ◽

Vol 35 (15_suppl) ◽

pp. e22512-e22512

Author(s):

Wenjun Xiong ◽

Wei Wang ◽

Jin Wan

Keyword(s):

Laparoscopic Surgery ◽

Gastrointestinal Stromal Tumors ◽

Esophagogastric Junction ◽

Laparoscopic Resection ◽

Stomach Wall ◽

Linear Stapler ◽

Stromal Tumors ◽

Estimated Blood Loss ◽

Laparoscopic Proximal Gastrectomy ◽

The Mean

e22512 Background: Laparoscopic surgery for small (<5 cm) gastric gastrointestinal stromal tumors (GIST) is now widely performed. However, laparoscopic resection of GIST in esophagogastric junction is technically difficult. Herein, we introduce various fashion of laparoscopic resection for small GIST in esophagogastric junction. Methods: Retrospective review of 40 consecutive patients with small GIST in esophagogastric junction who underwent attempted laparoscopic surgery. GIST in esophagogastric junction was defined as that the distance of the upper border of GIST from esophagogastric line was less than 2 cm. Three fashions of laparoscopic resection were performed: fashion A, laparoscopic wedge resection using linear stapler; fashion B, laparoscopic complete resection by opening the stomach wall and the stomach wall incision was closed with suture; fashion C, laparoscopic proximal gastrectomy with pyloroplasty. The data of clinicopathologic characteristics, operative course and short-term outcomes were analyzed. Results: All procedures were finished successfully and no operative relatively complication was recorded. Tumor in 24/40 (60%) patients was located in greater curvature. 70.1% (17/24) of them received fashion A and others (7/24) underwent fashion B. Tumor in 16/40 (40%) patients was located in lesser curvature. 18.8% (3/16) of them underwent fashion C and others (13/16) underwent fashion B. The mean operative time was 97.4±21.3 min and the mean estimated blood loss was 20.5±10.4 ml. The mean first time of flatus was 39.2±10.0 hours and the time of fluid intake was 40.1±11.7 hours. The mean hospital stay was 4.2±1.3 days. The mean diameter of tumor was 2.7±1.0 cm. Conclusions: Laparoscopic surgery for small GIST in esophagogastric junction is safe and feasible. The selection of various laparoscopic resection fashions was according to the tumor location.

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