scholarly journals Evaluation of lymphocytes CD4+ and CD8+ and expression of ZAP-70 kinase on CD3+ and CD19+ lymphocytes in obese patients undergoing laparoscopic cholecystectomy

2012 ◽  
Vol 27 (3) ◽  
pp. 872-879 ◽  
Author(s):  
Kamil Torres ◽  
Anna Torres ◽  
Andrzej Chrościcki ◽  
Ryszard Maciejewski ◽  
Sebastian Radej ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Obese Patients

272: Do the obese patients require less analgesia after laparoscopic cholecystectomy?

2007 ◽  
Vol 32 (5) ◽  
pp. 158-158
Author(s):  
D IONESCU ◽  
S MARGARIT ◽  
I GECZITOTH ◽  
C BERTEANU ◽  
A BALINTESCU ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Obese Patients

scholarly journals Day case laparoscopic cholecystectomy: Safety and feasibility in obese patients

2018 ◽  
Vol 49 ◽  
pp. 22-26 ◽  
Author(s):  
Matteo Gregori ◽  
Michelangelo Miccini ◽  
Daniele Biacchi ◽  
Jean-Charles de Schoutheete ◽  
Luca Bonomo ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Obese Patients ◽  
Day Case

scholarly journals Strategy to calculate magnesium sulfate dose in obese patients: A randomized blind trial

2021 ◽  
Author(s):  
Sebastião E. Silva Filho ◽  
Omar S. Klinsky ◽  
Joaquim E. Vieira
Keyword(s):  
Body Weight ◽  
Laparoscopic Cholecystectomy ◽  
Magnesium Sulfate ◽  
Postoperative Period ◽  
Ideal Body Weight ◽  
Morphine Consumption ◽  
Control Group ◽  
Obese Patients ◽  
Pain Scores ◽  
Ideal Body

Abstract BACKGROUNDMagnesium sulfate has analgesic properties in the postoperative period. Among obese patients, there is a gap in the knowledge of its pharmacology related to the use of real, ideal, or corrected ideal body weight in calculating its dose. This trial compared postoperative analgesia using actual and corrected ideal body weight.METHODSSeventy-five obese patients scheduled to undergo laparoscopic cholecystectomy under general anesthesia were randomly assigned to three groups. Patients in the control group received no magnesium sulfate; patients in the other two groups received magnesium sulfate 40 mg·kg− 1 of actual body weight or corrected ideal body weight. A ten nonobese patients group helped us as a model of the expected blood magnesium concentration after magnesium sulfate administration in general population.RESULTSPatients from the groups receiving magnesium sulfate showed significant reduction in morphine consumption (p ≤ 0.001) and pain scores (p = 0.006) in the postoperative period compared to the control group. There was no significant difference in the consumption of morphine (p = 0.323) or pain scores (p = 0.082) between these groups. There was no difference in the total duration of neuromuscular block induced by cisatracurium among the three groups (p = 0.181) or in the blood magnesium concentrations throughout the study.CONCLUSIONSMagnesium sulfate decreased postoperative pain and morphine consumption without affecting cisatracurium recovery time in obese patients undergoing laparoscopic cholecystectomy. Analgesic profile was similar in groups receiving magnesium sulfate calculated through real or corrected ideal body weight.TRIAL REGISTRATIONclinicaltrials.gov NCT04003688. (Date of registration: June 24, 2019)

scholarly journals Obesity is not a risk factor for either mortality or complications after laparoscopic cholecystectomy for cholecystitis

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yuta Enami ◽  
Takeshi Aoki ◽  
Kodai Tomioka ◽  
Tomoki Hakozaki ◽  
Takahito Hirai ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Laboratory Data ◽  
Operation Time ◽  
Similar Efficacy ◽  
Obese Group ◽  
Obese Patients ◽  
Normal Range ◽  
Surgical Morbidity ◽  
Male Patients ◽  
Wbc Count

AbstractObesity is a positive predictor of surgical morbidity. There are few reports of laparoscopic cholecystectomy (LC) outcomes in obese patients. This study aimed to clarify this relationship. This retrospective study included patients who underwent LC at Showa University Northern Yokohama Hospital between January 2017 and April 2020. A total of 563 cases were examined and divided into two groups: obese (n = 142) (BMI ≥ 25 kg/m2) and non-obese (n = 241) (BMI < 25 kg/m2). The non-obese group had more female patients (54%), whereas the obese group had more male patients (59.1%). The obese group was younger (56.6 years). Preoperative laboratory data of liver function were within the normal range. The obese group had a significantly higher white blood cell (WBC) count (6420/μL), although this was within normal range. Operative time was significantly longer in the obese group (p = 0.0001). However, blood loss and conversion rate were not significantly different among the groups, neither were surgical outcomes, including postoperative hospital stay and complications. Male sex and previous abdominal surgery were risk factors for conversion, and only advanced age (≥ 79 years) was an independent predictor of postoperative complications as observed in the multivariate analysis. Although the operation time was prolonged in obese patients, operative factors and outcomes were not. Therefore, LC could be safely performed in obese patients with similar efficacy as in non-obese patients.

scholarly journals Changes in lipid metabolism in the pre- and postoperative periods in obese patients with laparoscopic cholecystectomy

2021 ◽  
Vol 17 (1) ◽  
pp. 55-58
Author(s):  
A.O. Maisuradze ◽  
I.V. Chubuk
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Lipid Metabolism ◽  
Total Cholesterol ◽  
Low Density Lipoproteins ◽  
The Body ◽  
High Density Lipoproteins ◽  
Low Density ◽  
Obese Patients ◽  
Obese People ◽  
Group 1

Background. Changes in lipid metabolism indicators in the pre- and postoperative periods are due to frequent metabolic disorders in obese people and particular difficulties with the selection of appropriate therapy. In turn, the cause for metabolic changes in the body is the influence of a certain extreme situation — surgical intervention. Objective: to study the changes in lipid metabolism in the pre- and postoperative periods in obese patients with laparoscopic cholecystectomy. Materials and methods. The study involved 50 individuals (mean age — 47.0 ± 1.5 years), who underwent surgery for acute cholecystitis by laparoscopic cholecystectomy. The patients were divided into 2 groups: 1 — obese, 2 — non-obese. The level of triglycerides, total cholesterol, high-density lipoproteins (HDL), low-density lipoproteins (LDL), very-low-density lipoproteins (VLDL) was assessed in all patients and compared in the preoperative period and on days 1 and 5 after surgery. Results. The parameters of lipid metabolism in the pre- and postoperative periods in all groups had permissible fluctuations, given the fact that in obese patients lipids were initially increased compared to patients without obesity. In the postoperative period in group 1 on the first day, there was a decrease in triglycerides (1.1 ± 0.6 mmol/L) from the baseline, in total cholesterol (4.5 ± 0.3 mmol/L), an increase in HDL cholesterol (1.5 ± 0.2 mmol/L), a decrease in LDL (2.9 ± 0.2 mmol/L) and VLDL (1.0 ± 0.2 mmol/L). In group 2, indicators of triglyceri­des (0.6 ± 0.2 mmol/L), total cholesterol (3.4 ± 0.1 mmol/L), LDL (1.9 ± 0.3 mmol/L) and VLDL (0.8 ± 0.2 mmol/L) also tended to decrease and there was an increase in HDL (1.6 ± 0.1 mmol/L), but these values, regardless of their variation, were within the normal range. In group 1, three patients showed cognitive impairment, which was due to a significant increase in LDL over HDL and the possible development of atherosclerosis, which could lead to cerebrovascular accident. Conclusions. After conducting a study between two groups in which the lipids were studied, a variation in parame­ters was revealed in both groups, which is due to the characteristics of metabolism in such patients and the influence of surgical stress. Based on this, control and regulation of lipid values should be carried out in all patients with dyslipidemia, and in obese patients, additional consideration should be given to risk factors, concomitant diseases and possible complications.

scholarly journals Laparoscopic cholecystectomy in obese patients

2018 ◽  
Vol 40 (2) ◽  
pp. 54-58
Author(s):  
Doha N. Saad A ◽  
Eman I. Ahmed A ◽  
Hisham A.Al-Atrakchi A ◽  
Muzahm Al-khyatt A ◽  
Ahmed Tariq Hamed A
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Obese Patients

scholarly journals Safety and feasibility of single-incision laparoscopic cholecystectomy in obese patients

2017 ◽  
Vol 13 ◽  
pp. 34-37 ◽  
Author(s):  
Masaki Wakasugi ◽  
Masahiro Tanemura ◽  
Mitsuyoshi Tei ◽  
Kenta Furukawa ◽  
Yozo Suzuki ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Single Incision ◽  
Obese Patients ◽  
Single Incision Laparoscopic Cholecystectomy
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